Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Product Leader, Therapeutics Discovery

$148.6k - $276k

Genentech

The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche. Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CS CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. The Data and Digital Catalysts (DDC) department within the CS CoE is a diverse, curious and action‑driven team at the intersection of science, engineering and computation with ambition to advance our technical excellence. The focus of the team is on bridging the informatics and scientific communities to create a computational and data ecosystem that powers scientific discovery and accelerates decision making. We aim to modernise our ability to acquire, store, link, share, find and analyse data across the organisation through scalable and integrated solutions that truly make every data point count. Reporting to the Domain Head for Therapeutics Discovery, this Principal Product Leader will play a key role in defining and executing the strategy for a family of products that are critical for molecule design, making, testing, learning, and/or data lifecycle in drug discovery. The Therapeutics Discovery (TD) group within DDC is accountable for understanding the “why”, defining the “what” and prioritising the “when” for solutions that enable discovering life‑changing therapeutics. Our scientist stakeholders drive the discovery of therapeutic antibodies, small molecules and new modalities, leveraging best‑in‑class methodologies spanning antibody engineering, medicinal chemistry, automation, molecule profiling and AI/ML. The TD group is at the critical intersection of wet and dry labs and data. This role will be accountable for setting and executing on strategy within their product family to support multiple therapeutic modalities in partnership with drug discovery scientists, the domain head and other product family leads within TD and across other domains and REDs. This is an exciting opportunity to significantly impact and accelerate discovering diverse therapeutics that fundamentally make patients’ lives better. You will have the opportunity to work closely with Genentech’s top‑tier scientists and drug discovery experts. The Opportunity: As an integral member of this dynamic team, you will be: Define the strategy and product vision for a product family in the Therapeutics Discovery Domain to ensure we enable the highest impact scientific outcomes. Develop deep scientific and problem understanding, articulate the strategic product roadmap, nurture stakeholder relationships and drive delivery. Boldly advocate for future‑facing solutions, anticipate emerging capabilities, understand the Drug Discovery scientific landscape and influence the Roche/Genentech informatics ecosystem. Integrate all these factors in their roadmaps, budget projections and collaborations with implementation teams. Contribute to consolidation and deprecation of legacy systems and overall reduction of accumulated technical debt. Establish and cultivate strong internal and external partnerships and relationships with extended collaborators in DDC, CS CoE and beyond. Who You Are: In hiring new employees, we look for people who are inspired by our mission and can thrive with the collaborative, thorough and entrepreneurial spirit of our company culture. Because we know that employees are essential to our success in bringing novel medicines to patients, we are dedicated to remaining an extraordinary place to work and to providing employees with programmes, services and benefits that allow them to bring the best to the organisation and to their personal lives. The ideal candidate will satisfy many of the following requirements: Bachelor’s degree plus at least 7 years, or an advanced degree plus at least 2 years proven experience leading delivery of impactful internal solutions that drive significant outcomes. Experience working in a biotechnology setting and understanding scientific drug discovery processes is expected. Leads by example and acts as a mentor and coach for others. Influences without direct authority. Strong in Product Management, such as definition of product vision, strategic thinking and extended stakeholder management. Hands‑on domain expertise in the design‑make‑test‑learn aspects of biotechnology. Understanding of how scientific data is collected, managed, analysed and used in the discovery process. Experience documenting detailed software requirements, user stories, business processes and/or software specifications for both custom and Commercial‑Off‑The‑Shelf (COTS) systems. Highly collaborative and demonstrated ability to build positive relationships with internal and external partners. This includes working with globally distributed and cross‑functional teams. Outstanding oral and written two‑way communication skills. The proven ability to engage with and articulate vision, strategy and roadmap to diverse audiences, including scientific collaborators, technical teams and leadership. Relocation benefits are not available for this posting. The expected salary range for this position based on the primary location of California $148,600–$276,000. Actual pay will be determined based on experience, qualifications, geographic location and other job‑related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Genentech is an equal opportunity employer. It is our policy and practice to employ, promote and otherwise treat any and all employees and applicants on the basis of merit, qualifications and competence. The company's policy prohibits unlawful discrimination, including but not limited to discrimination on the basis of Protected Veteran status, individuals with disabilities status and consistent with all federal, state or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants. #J-18808-Ljbffr Genentech

Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Principal Product Leader, Therapeutics Discovery in South San Francisco, CA vacancy
  • $148.6k - $276k

     ...will guide the strategy for a family of products that support molecule design,...  ..., learning, and data lifecycle in drug discovery. You will work closely with Genentech’s...  ...scientists and cross‑functional teams across therapeutics discovery. Responsibilities Define the... 
    Principal
    Local area
    Relocation package

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    2 days ago
  • $148.6k - $276k

    Genentech in South San Francisco is seeking a Principal Product Leader to define and execute the product strategy for therapeutic discovery. This role emphasizes collaboration with top-tier scientists and requires deep knowledge of biotechnology and drug discovery processes... 
    Suggested

    Genentech

    South San Francisco, CA
    3 days ago
  • $148.6k - $276k

    F. Hoffmann-La Roche AG is seeking a product manager for their Data and Digital Catalysts department in California. You’ll define the product vision for a product family that aids in drug discovery, working with top scientists and cross-functional teams. The role requires... 
    Suggested

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    23 hours ago
  • $141.5k - $262.9k

     ...Engineering is seeking a visionary Principal Scientist to lead a high-...  ...assays to de-risk emerging therapeutic formats.Define molecular...  ...multidisciplinary research partners across Discovery Biology, Structural Biology,...  ....Sustained track record of productivity and substantial scientific... 
    Principal
    Full time
    Work at office
    Local area
    Relocation package

    Genentech

    South San Francisco, CA
    4 days ago
  • $167.4k - $310.8k

     ...sciences are transforming drug discovery and development. Roche’s...  ...We are seeking a Senior or Principal Machine Learning Scientist to...  ...evaluation workflows.Research-to-Production Impact: Partner with...  ...high-stakes problems in the therapeutic pipeline.Who you arePhD in Computer... 
    Principal
    Full time
    Local area
    Worldwide
    Relocation package

    Genentech

    South San Francisco, CA
    1 day ago
  •  ...in South San Francisco seeks a Senior Principal Research Scientist to lead Protein Sciences...  ...team, and solve challenging protein-production problems across multiple programs. You...  ...systems, contributing to a diverse drug-discovery portfolio. You will work onsite four days... 
    Principal

    IDEAYA Biosciences

    South San Francisco, CA
    2 days ago
  • $159k - $207k

     ...achieve our goal of delivering meaningful therapeutics to patients.We are seeking a Principal Scientist to join our Formulation & Drug Product Development team to serve as a...  ...decision-making including collaborating with Discovery Biotherapeutics, Bioprocess Development... 
    Principal
    Contract work
    Local area

    Denali-Therapeutics

    South San Francisco, CA
    4 days ago
  • $159k - $207k

     ...challenges of our time. Denali Therapeutics is a biotechnology company...  ...the vision that scientific discovery energetically applied to translational...  ...launch of its first product, AVLAYAH, approved through...  ...countries, we are seeking a Principal Scientist to join our Large... 
    Principal
    Contract work
    Local area

    Denali Therapeutics

    South San Francisco, CA
    23 hours ago
  • $168.6k - $313k

     ...experienced Medicinal Chemist (Senior Principal Scientist) to join our...  ...position within our Peptide Therapeutics department, focused on...  ...significant contributor and a proven leader, responsible for optimizing...  ...to solve complex drug discovery challenges and drive projects... 
    Principal
    Local area
    Relocation package

    Genentech

    South San Francisco, CA
    1 day ago
  • $176.2k - $277.3k

     ...combine leading drug discovery capabilities and world...  ...scientist in the role of Principal Scientist in the South...  ...in partnership with therapeutic area scientists As a member...  ...a global health care leader with a diversified...  ...vaccines and animal health products. The difference... 
    Principal
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    MSD Malaysia

    South San Francisco, CA
    5 days ago
  • $143.2k - $265.9k

     ...seeking a creative and highly motivated Principal Scientist, Medicinal Chemist to join...  ...leadership position within the Peptide Therapeutics department. In this lab-based leadership...  ...with strategic oversight, driving the discovery and optimization of peptide therapeutics... 
    Principal
    Local area
    Relocation package

    Genentech

    South San Francisco, CA
    2 days ago
  • $177k - $235k

     ...commitment to curiosity-driven discovery science, and, with academic...  ...Senior Scientist / Principal Scientist to bridge the gap...  ...looking for a deep expert in therapeutic antibody development who is...  ...vitro library design, protein production, and screening assaysAbility... 
    Principal

    Calico Life Sciences

    South San Francisco, CA
    1 day ago
  • $192.5k - $357.5k

     ...computational sciences are transforming drug discovery and development. Roche’s Research and...  ...machine learning. We are seeking a Principal Machine Learning Engineer to join our Foundation...  ...systems for foundation models. Own the production Python/PyTorch codebases that turn fast... 
    Principal
    Full time
    Local area
    Worldwide
    Relocation package

    Genentech

    South San Francisco, CA
    4 days ago
  • $161.6k - $300k

    The PositionPrincipal Business Product ManagerWhy GenentechWe're passionate about improving patient lives and building healthier communities...  ...or business analytics product management across multiple therapeutic areas.Product Management Expertise: Proven experience in a... 
    Principal
    Full time
    Apprenticeship
    Local area
    Immediate start
    Relocation package

    Genentech

    South San Francisco, CA
    4 days ago
  • $182.1k - $338.3k

     ...functions (including USM, Research, Product Development, Commercial, and...  ...and affordable for all.The Principal Content & Evidence Submission...  ...the Squad in the assigned therapeutic area(s). Their expert...  ...coach, and advise teams and leaders to develop valuable solutions... 
    Principal
    Full time
    Local area

    Genentech

    South San Francisco, CA
    3 days ago
  • $143k - $286k

     ...Position Summary... What you'll do... Role summary: As a Principal Product Manager, you will lead product strategy across multiple...  ...at a strategic level. About the team: The Walmart discovery experience team focuses on enhancing the top-of-funnel shopping... 
    Principal
    Full time
    Temporary work
    Part time

    Walmart

    San Bruno, CA
    1 day ago
  • $173.1k - $321.5k

     ...people we love.The Senior Principal Scientist serves as the scientific leader for Bioanalytical...  ...development of cell therapy products. The Senior Principal...  ...characterizing the in vivo fate of therapeutic cells, including...  ...in the field of drug discovery or development with... 
    Principal
    Full time
    Local area
    Relocation package

    Genentech

    South San Francisco, CA
    4 days ago
  • $149.52k - $175.9k

     ...DescriptionProduct Managers at U.S. Bank are customer obsessed in driving product visioning, planning and development to deliver on our human +...  ...breaks down work into actionable steps to facilitate product discovery, design, development and delivery.Manages the end-to-end... 
    Full time
    Local area
    Shift work

    US Bank

    San Francisco, CA
    2 days ago
  •  ...leading design agency in South San Francisco is in search of a Principal Experience Designer to shape their digital-forward design vision...  ...involves collaborating with senior stakeholders to enhance product features and ensure the alignment of business priorities with user... 
    Principal
    Full time

    R&D Partners

    South San Francisco, CA
    1 day ago
  • Merck & Co., Inc. is seeking a Principal Scientist for the South San Francisco Discovery Biologics group to lead antibody discovery programs with a focus on...  ...requires an established track record in antibody therapeutics and leading high-performance teams. You will collaborate... 

    MSD Malaysia

    South San Francisco, CA
    5 days ago
  • $173.1k - $321.5k

     ...development and marketed products. This Senior Principal Scientist role is intended...  ...assessment of Genentech therapeutics by creating a best weight...  ...and decision-making from discovery and candidate selection through...  ...to project teams, senior leaders, and regulatory audiences... 
    Principal
    Full time
    Local area
    Immediate start
    Relocation package
    3 days per week

    Genentech

    South San Francisco, CA
    1 day ago
  • $278.53k - $345.04k

     ...within the creator ecosystem.In search and discovery, you will contribute to the core systems...  ...research efforts into the Roblox products.Collaborate with other teams within Roblox...  ...ambassador for Roblox.You have:You have 7+ (for principal) or 4+ (for senior) years of experience... 
    Principal
    Full time
    Work experience placement
    H1b
    Work at office
    Local area
    Visa sponsorship
    Monday to Friday

    Roblox

    San Mateo, CA
    1 day ago
  • $198.9k - $369.3k

     ...development and marketed products. This Senior Principal (SE8) role is intended for...  ...independent pathology strategy from discovery and candidate selection...  ...-functional initiatives, therapeutic-area or expert working...  ...to project teams, senior leaders, and regulatory audiences.... 
    Principal
    Full time
    Local area
    Immediate start
    Relocation package
    3 days per week

    Genentech

    South San Francisco, CA
    4 days ago
  • Merck in South San Francisco seeks a Principal Scientist with extensive experience in antibody discovery and B-cell biology to lead and innovate across discovery programs. You will guide in vivo strategies, collaborate with cross-functional teams, and contribute to a high... 
    Principal

    Merck

    South San Francisco, CA
    5 days ago
  • $143.2k - $265.9k

     ...announce an opportunity for a Principal Scientist, Lab Head, to join...  ...will lead a highly productive research team and integrate...  ...to identify new targets and therapeutic hypotheses, and to advance transformative...  ...high-performing team in the discovery and advancement of novel... 
    Principal
    Full time
    Local area
    Relocation package

    Genentech

    South San Francisco, CA
    1 day ago
  • Genentech's Department of Protein Sciences in South San Francisco seeks a Principal Scientist in Structural Biology to drive drug discovery by integrating structural data, computational modeling, and biophysical insights. You will oversee protein construct design, expression... 
    Principal

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    3 days ago
  • $155k - $200k

     ...the epigenome, a new therapeutic mechanism to restore regenerative...  ...is seeking a Senior/Principal Scientist with deep...  ..., you will lead the discovery, development, and...  ...serve as a technical leader within our bioanalytical...  ...Experience developing products in emerging therapeutic... 
    Principal

    Quiet Capital

    South San Francisco, CA
    23 hours ago
  • $243k - $328.5k

     ...of millions of customers worldwide using products such as TurboTax, Credit Karma,...  ..., adopt, and grow with QuickBooks. As a Principal PM on Product Growth, you'll own strategy...  ...-velocity experimentation culture, from discovery and hypothesis generation through A/B testing... 
    Principal
    Worldwide
    Flexible hours
    Shift work

    Intuit

    San Francisco, CA
    2 days ago
  • $143.2k - $265.9k

     ...OPPORTUNITYThe Department of Immunology Discovery at Genentech is excited to...  ...an opportunity for a Principal Scientist, Lab Head, to lead...  ...will lead a highly productive research team, integrating efforts...  ...to identify new targets and therapeutic hypotheses, and to advance transformative... 
    Principal
    Full time
    Local area

    Genentech

    South San Francisco, CA
    1 day ago
  • Genentech in South San Francisco, CA seeks a Senior Manager, Product Operations - Content Management & DAM to translate product strategy into scalable enablement and operational practices. You’ll collaborate with Product, Tech, Content, Data, and Marketing to drive adoption... 

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Product Leader, Therapeutics Discovery. Be the first to apply!