Senior Fullstack Engineer
Orchestra Bio, Inc
Senior Fullstack Engineer
Orchestra helps companies navigate the journey from discovery to medicine by connecting science, operations, and finance in an intelligent platform. We're on a mission to make every R&D dollar count.
Developing new medicines is a societal imperative to improve human health and reduce medical costs. Brilliant science needs effective management to develop breakthrough medicines that reach patients. We aim to bring the same level of sophistication to scientific development that modern tools brought to software development. While software teams can ship updates daily, R&D organizations face unique challenges: years long development cycles, complex interdependencies, and high-stakes decisions that can make or break billion dollar programs.
Founded by early Benchling leaders, we just emerged from stealth with $20M in funding from 8VC, Andreessen Horowitz, Insight Partners, Definition, and Haystack to transform how biotech companies operate. Our customers are working on society's most important challenges, including neurodegeneration, cancer, metabolic disease, and biomanufacturing. We're looking for engineers who are excited about building software that helps scientific organizations operate more effectively.
We're seeking a Senior Fullstack Engineer to join our growing team in San Francisco. You'll work with our team to create complex but intuitive products to manage R&D.
Challenges You'll Tackle
Complex Decision Making : Build interactive tools that help organizations model different paths to market for their discoveries, assessing complex trade offs between time, money, and technical risk. Our users need to understand how decisions today affect their programs years into the future.
Organizational Alignment: Create intuitive interfaces that help diverse teams (scientists, program managers, executives) understand how their work connects to broader company goals. This includes designing clear ways to visualize complex dependencies and communicate progress across teams.
Scientific Operations: Design interfaces that scientists and researchers use daily to manage their studies, track progress, and coordinate with their teams. This requires crafting experiences that empower rather than get in the way of work.
AI Powered R&D Management: Leverage LLMs to help teams generate and evaluate scenarios, infer scientific progress and risks from unstructured data, and surface critical insights from across their R&D portfolio.
What Sets You Apart
Complexity: You understand how to build software for complex, interconnected domains where changes in one area cascade across multiple dimensions. You're excited about creating systems that handle the unique challenges of long term, high stakes R&D programs.
Agency: You're drawn to environments where you can shape both the technical architecture and product direction. You enjoy the responsibility of building foundational systems that will scale, balancing the speed needed at an early stage company with the craftsmanship required for complex, mission critical software.
Curiosity: You're genuinely curious about how breakthrough products are developed and excited about building software that helps scientific organizations operate more effectively. You want your technical work to contribute to bringing medicines and other innovations to market.
Required
6-8 years of frontend or fullstack engineering experience
Deep expertise in React and modern JavaScript/TypeScript
Strong understanding of frontend architecture
Excellent communication skills and ability to collaborate with product and design
Proven track record of working effectively in small, fast-moving engineering teams
Preferred
Experience building sophisticated data visualization UIs
Background in high domain complexity
Track record of mentoring other engineers
$150k - $220k
...'ll be joining at the ground floor — working closely with senior technical leadership and across multiple product engineering teams to build scalable, high-impact software. We're looking for a Senior Fullstack Engineer who thrives in a fast-moving, collaborative environment...SeniorFull timeRemote workVisa sponsorship$130k - $160k
...Senior Fullstack Engineer (Team Builder & Full-Stack Specialist) Stack: JavaScript (Node/Lambdas), MongoDB, Angular, AI-Integrated Workflow If you are unable to complete this application due to a disability, contact this employer to ask for accommodation or an alternative...SeniorFull timeFor contractorsWork at officeLocal areaRemote workFlexible hours$180k - $195k
...First Round and Construct Capital. Read about our recent Series B here on TechCrunch! We’re looking for a NYC based senior fullstack engineer to join our team and build the future of high sustainability commerce! Our engineering team is small but we ship fast and...SeniorFull timeWork at office- ...includes company builders and tech entrepreneurs, as well as engineering, product and sales experts. Factify has raised a very significant... ...and academia leadership positions. We’re looking for a Senior Backend Engineer to lead and join our backend engineering...SeniorFull time
- Overview Notable is the leading intelligent automation company for healthcare. Customers use Notable to drive patient acquisition, retention, and reimbursement, scaling growth without hiring more staff. We don’t just make software. We are on a mission to fix the broken...SeniorFull timeWork experience placement
- ...quality standards, showcasing success across diverse engagements. ~Promote client success across the team by collaborating with engineers, designers, and managers to understand user pain points, anticipate potential problems, and iterate on solutions that drive client...SeniorFull timeRemote work
- ...throughout San Francisco, Seoul, Tokyo, Taipei, and Ljubljana. About this role We are looking for a backend leaning full-stack engineer to work on building novel AI-powered product experiences. The ideal candidate will have experience working in close coordination...SeniorFull timeLive inWork at office
$190k - $230k
...founding team brings expertise across machine learning, UI/UX, large language models, and medicine. We’re seeking exceptional fullstack engineers to join us at our early stage. Together, we will create the AI layer that will redefine healthcare for the better. Job...SeniorFull timeWork at office2 days per week3 days per week$170k - $220k
...Senior Full-stack Engineer Location: Hybrid- San Francisco OR Palo Alto Office, Tuesday/Thursday The difference you will make We're looking for a senior fullstack engineer to join our growing team as we rapidly scale towards our mission of revolutionizing healthcare...SeniorFull timeH1bWork at officeImmediate startFlexible hours$180k - $240k
...out our talent principles as we march together to achieving our mission. About the Job Blackbird is looking for a Senior Fullstack Engineer to own Flycar, our restaurant payments terminal used by thousands of restaurants. You'll build the software servers and managers...SeniorFull timeLive outImmediate start$140k - $190k
...leading health systems, and the features our users touch every day are at the center of that growth. We're looking for a Senior Fullstack Engineer who's passionate about using their skills to unlock efficiency for hospitals and their suppliers — someone who wants to own...SeniorFull timeRemote work$200k - $270k
Role Description As an engineer on the Network Services team, you'll work on software that makes the open network behind Bluesky and the broader developer ecosystem tick. ~Contribute to products, documentation, and developer tools that extend Bluesky's reach into the...SeniorFull time$200k - $225k
...our patients convenient access to reasonably-priced medications without ever needing to step foot in a pharmacy. As a Senior Full-Stack Engineer , you will have a hand in architecting the technology and customer experience that are pivotal to multiple web products...SeniorFull timeLive out€68k - €78k per year
...innen für eine einzige Schublade, sondern Engineers, die das große Ganze sehen – vom... ...Frontend, Backend und alles dazwischen. Fullstack heißt bei uns Fullstack. ~Architektur... ...innen und koordinierst Lösungen mit anderen Seniors. Qualifications ~Mindestens 4 Jahre...SeniorFull timeFlexible hours- ...What You’ll Do Design and influence decisions that affect our fullstack architecture for scalable, AI-powered healthcare solutions... ...practices for code quality, testing, and deployment Mentor junior engineers, guiding fullstack engineering, design patterns, and coding...SeniorFull timeWork at office
- ...to win as a startup. What are we looking for? Complete is at an exciting inflection point and we’re looking for Senior or Staff Engineers to help scale us to a $XXM+ in ARR. You'll be a great fit if you like to move with urgency and high agency. We're engineers...SeniorFull timeWork at office
$157k - $193k
...Summary: As a Senior Full Stack Engineer at Topstep, you’ll play a key role in building the distributed systems that power our trader experience. You’ll help define and evolve the architecture that serves as the backbone of our payments and purchasing platform,...SeniorFull timeLocal areaRemote work- ...superintelligence. To achieve this, we need more great engineers. The work affects millions of people... ...! The Role We're looking for a fullstack engineer to build the product our... ...-effective personalized agent As a senior fullstack engineer, you'll own features...SeniorFull time
- ...medical professionals. As the product continues to scale, the engineering team is expanding to support increasingly complex integrations... ...requirements, and platform reliability. We are looking for a Senior Full Stack Engineer with strong backend expertise in NestJS...SeniorFull timeRemote work
$190.41k - $224.01k
...We’re changing both of those things. We’re building a Growth Engineering team responsible for turning Fetch’s web presence into a real... ...engage and convert visitors into Fetch users. We’re building a senior team to do this work. We believe experienced engineers get...SeniorFull timeRemote work- ...businesses to move money programmatically while maintaining strict regulatory requirements. The Role We're looking for a Senior Fullstack Engineer who is primarily frontend-focused but comfortable contributing across the stack. You'll own the React and TypeScript...SeniorRemote jobFull timeFlexible hours
$150k - $300k
Role Description We are looking for a Senior Fullstack Engineer who thinks like a Product Owner. You will work closely with our Product and Business teams to understand our customers’ pain points, design solutions, and actually write and ship code to directly solve problems...SeniorFull timeWork at officeRemote work$154.45k - $185.33k
Role Description The Grafana Cloud Observability department is focused on enabling developers to understand the health and performance of their applications and infrastructure in any environment by providing tools to instrument their code, ingest observability data into...SeniorFull timeLocal areaRemote work- Role Description As part of a team of senior engineers, design, develop, and grow the Lingo.dev products: ~Web applications - Routing, navigation, onboarding flows, user experience, performance ~Open source tools - CLI, webpack/vite plugins ~Backend APIs - encapsulation...SeniorWork experience placementRemote workTrial periodFlexible hours
$135k - $165k
Role Description We're looking for a Senior Software Engineer to join the Clasp Finance engineering team, a small, high-impact group working at the intersection of financial operations, product, and data. You will report to the Engineering Director, Lending and work...SeniorFull timeFlexible hours- Role Description As a Senior Full Stack Engineer, you will own meaningful parts of the platform end to end. You will take ambiguous problems, work out the right approach, and ship reliable, high-performance systems that real brands depend on every day. You will work...SeniorFull time
- Role Description Buscamos un/a Desarrollador/a Fullstack Semi Senior o Senior con sólida experiencia en desarrollo frontend y backend, orientado/a a la construcción de soluciones escalables, resilientes y de alta calidad. El rol tendrá participación activa en el diseño...SeniorFull time
€75k - €90k per year
Role Description As a Senior Full Stack Engineer, you'll work at the intersection of engineering and product to shape how our users build with Hygraph. You'll ship features that solve real customer problems, contribute to our CMS core, extend our platform capabilities,...SeniorFull timeRemote workWorldwide- Role Description We are looking for a Senior Full-stack Engineer to contribute to multiple client-facing web projects, building and maintaining scalable applications using .NET technologies and modern frontend frameworks. This role is ideal for an engineer who enjoys working...SeniorFull timeRemote work
$180k - $210k
Role Description We're looking for a Senior Fullstack Engineer who is equally comfortable shaping a React interface, designing a Rails service, and reasoning about the database and infrastructure beneath it. This is a core product role: you will own meaningful features...SeniorFull timeTemporary workImmediate startRemote workWork from home
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Fullstack Engineer. Be the first to apply!
- full stack developer intern United States
- junior full stack developer United States
- full stack react developer United States
- mean stack developer United States
- full stack engineer United States
- full time engineer United States
- full stack developer remote United States
- junior full-stack web developer United States
- senior full stack web developer United States
- full stack developer contract United States















