Senior Director - AI

Job-ID: 394492Category: Technology ArchitectureLocation: Rochester, MN, United StatesSchedule: Full timePosted: 2026-10-27Hours / Pay Period: 80Benefits Eligible: YesRemote worker: Flexibility of both remote and on-site workCompensation Detail: $248,227.20 - $372,361.60/ year. Education, experience and tenure may be considered along with internal equity when job offers are extended.Schedule Details: M-F 8am-5pm This is a hybrid position and must be located within 100 miles of the Rochester, MN Mayo campus with an expectation to work on-site approximately 1-2 days per week.Weekend Schedule: As business needs dictateUnion Job: NoArea of Interest 1: DigitalMarketing Category 1: Information TechnologyInternational Assignment: NoOvertime Rule: Salaried employee who does not receive overtime payThe Senior Director, AI leads the engineering and research team that builds and delivers Mayo Clinic DigPath's digital-biology technology platforms, accountable for translating the organization's vision into validated, deployed products. Working closely with the Vice President, Digital Biology, the Chief Medical Officer, and the Chief Science Officer, the Senior Director helps shape technical direction and owns its execution—the roadmap, delivery, and technical quality for DigPath's core model and platform portfolio, including foundation and task-specific models, AI Virtual Cells, biological digital twins, and digital biomarker discovery. Directing a multidisciplinary team of AI/ML engineers, software developers, and research scientists, the Senior Director turns clinical and scientific priorities into engineering execution - partnering with the CMO for clinical relevance and the CSO for scientific rigor - to consistently ship breakthrough tools with speed, technical excellence, and unwavering focus on Mayo Clinic's core value: the needs of the patient come first.The leader's primary responsibility will be managing highly matrixed cross-functional activities and personnel, with oversite for departmental AI governance, technology, and operations. The leader will also work alongside Chairs representing the department across Mayo Clinic, partnering closely with Shield leaders, and coordinating with other enterprise and Site leaders and governance bodies.This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.QualificationsBachelor’s degree in a relevant field, such as Business Administration, Computer Science, AI/ML Engineering, Software Engineering, Information Systems, Design, or Health Informatics plus 10 years of related experience, including executive-level management of digital, technology, security, or product teams in complex organizations.Master's degree in Business, Law, Computer Science, Engineering, Design, Healthcare Administration, or a related field preferred. Experience in integrated healthcare, academic medical centers, or regulated industries preferred.About the organization Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.Equal OpportunityAll qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization. About the companyWhy Mayo Clinic Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. Benefits HighlightsMedical: Multiple plan options.Dental: Delta Dental or reimbursement account for flexible coverage.Vision: Affordable plan with national network.Pre-Tax Savings: HSA and FSAs for eligible expenses.Retirement: Competitive retirement package to secure your future.