Research Associate - Assay Development

We are seeking a highly motivated Research Associate (2-5 years of experience) to support and accelerate assay development efforts. This role will work closely with other members of the Product Development team to execute, optimize, and characterize single-cell workflows and reagents.

This is a hands-on laboratory role ideal for someone who thrives in a fast-paced startup environment and wants to contribute meaningfully to building robust, scalable genomic products.

Key Responsibilities

• Execute single-cell assay development experiments under the direction of senior scientists.
• Prepare and characterize reagents used in single-cell workflows (e.g., enzymes, buffers, primers, beads, barcoding reagents).
• Perform core molecular biology techniques including nucleic acid manipulation, reverse transcription, PCR/qPCR, ligation, enzymatic reactions, and NGS library preparation.
• Design and execute optimization experiments using structured experimental design (DOE) approaches to evaluate assay parameters and reagent formulations.
• Prepare and test buffer and reagent formulations and characterize their performance in assay workflows.
• Run assays and optimization experiments using liquid-handling automation platforms (e.g., Agilent Bravo) and assist in adapting workflows for automation.
• Perform and maintain mammalian cell culture to support assay validation and testing workflows.
• Generate high-quality, reproducible data and maintain detailed experimental records.
• Help develop reagent QC and assay performance testing methods using qPCR, ddPCR, NGS-based, and other analytical readouts.
• Help scale workflows for robustness, reproducibility, and eventual automation.
• Maintain laboratory organization, inventory, and equipment calibration.
• Contribute to SOP development and documentation as processes mature.

Qualifications

• Bachelor's or Master's degree in Molecular Biology, Biochemistry, Genetics, Bioengineering, or related field.
• 2-5 years of relevant industry or advanced academic laboratory experience.
• Strong hands-on molecular biology skills (PCR, qPCR, enzymatic reactions, NGS library prep).
• Experience working with complex biological workflows requiring careful technique and documentation.
• Demonstrated ability to generate reproducible data and troubleshoot experiments.
• Highly organized with strong attention to detail.
• Comfortable working in a dynamic startup environment with evolving priorities.

Preferred Qualifications

• Experience with single-cell genomics workflows (e.g., scRNA-seq, barcoding methods, droplet or bead-based systems).
• Familiarity with bead handling, surface chemistry, or conjugation methods.
• Experience with mammalian cell culture and sterile technique.
• Experience with NGS QC methods (Bioanalyzer, TapeStation, Qubit, fragment analysis).
• Exposure to automation platforms or high-throughput workflows.
• Experience using basic statistical tools or data analysis software.

What Success Looks Like in This Role

• Consistently produces high-quality, reproducible data.
• Increases experimental throughput and reliability for the assay development team.
• Proactively identifies workflow improvements.
• Operates with independence while collaborating effectively.
• Embodies and reinforces a culture of rigor, efficiency, and accountability.