Systems Engineer (R1-R4)

Job ID: R-107947Company: LillyLocation: Concord, North Carolina, United States of AmericaJob Type: Full TimeCategory: Information TechnologyPosted Date: 2026-06-26At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. Eli Lilly and Company seeks a Systems Engineer (R1-R4) to design, develop, implement, enhance, and maintain Manufacturing Execution System (MES) applications for pharmaceutical manufacturing. Integrate pharmaceutical production operations with business systems. Conduct testing, troubleshooting, and maintenance of MES applications to ensure system reliability and data accuracy. Document processes and procedures for pharmaceutical manufacturing systems to meet quality and compliance standards. Ensure MES systems follow pharmaceutical industry-specific regulations, including Food and Drug Administration (FDA) guidelines and Good Manufacturing Practices (GMP) requirements, internal policies and procedures, and local requirements. #LI-DNIPosition requires a Bachelor’s degree in Pharmacy, Pharmaceutical Science, Computer Science, or a related scientific field, followed by 5 years of progressively responsible experience with MES applications in a pharmaceutical setting. Experience must include a minimum of: 5 years of experience with manufacturing standards, including ISA-95, Open Platform Communications, and data historians; 5 years of experience with computer systems validation; 3 years of experience with Rockwell Automation Pharma Suite, Emerson Syncade, Siemens Camstar, or Werum PAS-X; and 3 years of experience with integrating MES systems with other enterprise systems, including Enterprise Resource Planning (ERP) and Supervisory Control and Data Acquisition (SCADA). Part-time telecommuting permitted. Up to 15% domestic and international travel required. #LI-DNIJob location: Concord, NC.To apply, please visit and enter job requisition number R-107947 when prompted. Alternatively, please send your resume, cover letter, and a copy of the ad to: Eli Lilly and Company, Lilly Corporate Center, Drop Code 1093, Indianapolis, IN 46285.Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form () for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (View email address on click.appcast.io), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is$154,669.00 - $177,869.35 per yearFull-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.#WeAreLillySkillsmanufacturing execution systemrockwell automation pharma suitecomputer systems validationpharmaceutical manufacturingisa-95open platform communicationsenterprise resource planningsupervisory control and data acquisitionsystem integrationdata historiansemerson syncadesiemens camstarwerum pas-xprocess documentationtesting and troubleshootingstakeholder communication