Global Development Lead, Internal Medicine, Sr. Director (non-MD)

Role Summary The Global Development Lead (GDL) represents Clinical on the Global Medicine Team and is the single clinical point of accountability for clinical development for assigned asset(s) in Internal Medicine, Research & Development, Pfizer. The GDL leads the cross‑functional Clinical Development Team—clinical, clinical pharmacology, statistics, safety, commercial, patient access, and operations—to design, execute, and interpret studies supporting worldwide regulatory submissions. The GDL creates and gains endorsement for the Clinical Development Plan and associated protocol design documents, partners with clinical and clinical operations colleagues throughout study lifecycles, and may collaborate with external companies under Pfizer’s Partner of Choice model. The role is also eligible for other clinical leadership opportunities within the Obesity portfolio. Responsibilities Partner effectively with the Medicine Team Lead to negotiate tradeoffs, milestones, and ensure delivery of clinical programs in line with agreed timelines and budget. Develop a comprehensive clinical development plan to secure approval and reimbursement globally (including China and Japan), including pediatric investigation and study plans and protocol design documents alongside trial clinicians for feasibility and optimal operational execution. Provide product/program‑specific input for target product profiles. Bring innovative thinking and bold decision‑making across clinical development programs and individual studies. Develop enabling strategies—digital, innovation, and patient engagement—to support clinical studies. Collaborate with trial clinicians on governance reviews (Science/Operations) for assigned studies; provide development strategy input and insights. Support clinical review of data—CRF design, signal interpretation, adverse event contextualization—as required. Provide specialized medical monitoring support for trial teams when needed. Partner in trial‑level statistical analysis plans, table‑listing‑figures, and database release with statistics and programming teams. Develop submission‑level deliverables (IAP, IARP, TLFs) and deliverables such as SCE and SCS. Support interpretation and communication of clinical trial data. Review and approve submission‑level safety narrative plans. Support product label development and maintenance. Engage key external stakeholders (ad boards, steering committees, DMC, adjudication committees, patients, patient advocates) to generate strategic insights for development strategy and product development decisions. Provide regulatory submission support (DSUR, PBRER, disclosure deliverables) and product defense. Ensure compliance with internal SOPs and external regulatory standards. Review IIR proposals. Basic Qualifications PhD or PharmD Education PhD or PharmD Experience Background in chronic weight management, endocrinology, or internal medicine with experience in Phase 1–3 clinical development and translational medicine. 8+ years of relevant experience and a track record of success in academia and/or the biopharmaceutical industry in clinical research and development. Extensive knowledge of clinical development, global and regional regulation, ICH/GCP, and adverse event management. Demonstrated clinical/medical, administrative, and project‑management capabilities, effective communication skills, and ability to work collaboratively across the organization. Experience managing and training large teams in clinical development. Experience in designing and launching large teams preferred. Broad, diverse leadership experience, including influencing peers, coaching others, guiding colleagues to achieve meaningful outcomes, and creating business impact. Competency Requirements Medical/Scientific credibility and excellence—including a track record of achievement in pharmaceutical development and understanding of disease area complexities. Management experience in a highly complex matrixed environment, able to influence cross‑functional teams. Leadership: persuasive and effective leader of staff. Influencing: manages and motivates internal teams on clinical trials. Conflict management: mentors/coaches others, handles disputes, and supports decisions—even when unpopular. Team building: fosters open dialogue, promotes responsibility, and creates strong morale. Accountability: takes personal responsibility for results and pushes for excellence. Change agility: demonstrates poise amid uncertainty and delivers results during organizational change. Non‑standard Work Schedule, Travel, or Environment Requirements Up to 30% travel may be required. Work Location Assignment This is a hybrid role requiring you to live within commuting distance and work on‑site an average of 2.5 days per week. Compensation and Benefits The annual base salary ranges from $214,900 to $358,100. The position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and a long‑term incentive program. Benefits include a 401(k) plan with Pfizer matching, a retirement savings contribution, paid vacation, holiday and personal days, caregiver/parental and medical leave, and health coverage covering medical, prescription drug, dental, and vision. Relocation Assistance May be available based on business needs and eligibility. Employment Eligibility Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (TN, O‑1, H‑1B, etc.) is not available for this role now or in the future. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state laws. Reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the Sunshine Act. Contact the Talent Acquisition representative for details. EEO & Employment Eligibility Pfizer is committed to equal opportunity in employment for all employees and applicants regardless of race, color, religion, sex, sexual orientation, age, gender identity or expression, national origin, disability, or veteran status. Pfizer complies with all applicable laws regarding nondiscrimination and work authorization. Pfizer is an E‑Verify employer and requires permanent work authorization in the United States. #J-18808-Ljbffr Pfizer