Senior Manager, Tax

SENIOR MANAGER, TAX
Billerica, MA (HYBRID)
Quanterix is a global leader in ultra-sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development. Its vision is to lead the next era of precision biomarker science to power earlier detection, better decisions, and improved human health. Its mission is to make biology measurable at its most fundamental level, delivering earlier insight when it matters most. Across discovery to clinical applications, Quanterix empowers scientists and healthcare providers to improve patients' lives through detection and understanding of disease. Its proprietary Simoa technology delivers industry-leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional limits. With more than 3,400 peer-reviewed publications, Quanterix has been a trusted partner to the scientific community for nearly two decades. In 2025, Quanterix acquired Akoya Biosciences, The Spatial Biology Company, adding multiplexed tissue imaging with single-cell resolution to its portfolio. Together, the combined company offers a uniquely integrated platform that connects biology across blood and tissue-advancing precision medicine from discovery to diagnostics.
ROLE SUMMARY:
We are looking for an experienced, hands-on Tax Manager to serve as our tax leader. Reporting to the VP, Corporate Controller, this role is responsible for core domestic and international tax operations, including income tax compliance, indirect tax compliance, tax accounting, and related SOX controls for a growing global public company.
You will partner closely with Accounting, SEC Reporting, Treasury, Legal, FP&A, Operations, and external advisors to support timely compliance, accurate reporting, scalable processes, and business-informed tax decisions. The successful candidate is a self-starter who can take ownership of recurring tax processes and provide clear tax insights to accounting and finance leadership.
WHAT YOU'LL DO:
Tax Compliance & Reporting

• Manage the Company's global income tax compliance processes, including U.S. federal, state, local, and international tax filings, ensuring timely, accurate, and well-supported submissions across all jurisdictions.
• Oversee quarterly and annual tax accounting and reporting under ASC 740, including review of tax provisions, effective tax rate analyses, deferred tax assets and liabilities, uncertain tax positions, and related SEC reporting disclosures.
• Review and coordinate state and local tax filings, including income, franchise, gross receipts, sales and use, property, and other indirect tax returns, ensuring timely compliance and appropriate support across relevant jurisdictions.
• Manage VAT/GST compliance across applicable jurisdictions, including review of periodic VAT returns, supporting reconciliations, payments, refund claims, and related indirect tax filings.
• Support global transfer pricing processes, including intercompany agreements, documentation, operational compliance, and coordination with external advisors.
• Lead Article 23 import VAT reporting and related indirect tax compliance processes, including coordination with logistics, customs brokers, finance, and external advisors to ensure accurate reporting, documentation, and reconciliation of import VAT positions.
• Coordinate R&D tax credit studies, Section 382 analyses, and similar work with external third-party tax advisors.

Tax Accounting, Controls, & Audit Support

• Maintain strong tax governance, SOX controls, process documentation, and audit-ready support for tax accounting, compliance, and reporting activities in a publicly traded company environment.
• Support tax audits and inquiries, including preparation of responses to taxing authorities, coordination with external auditors and advisors, and development of clear, well-supported technical analyses.
• Manage and coordinate third-party tax advisors, including scope, deliverables, timelines, and budgets.
• Prepare and review technical tax memoranda, position papers, return-to-provision analyses, and other documentation for management, auditors, and external advisors.
• Communicate complex tax matters clearly and effectively to finance leadership and cross-functional stakeholders.

Tax Improvements

• Evaluate SALT nexus, apportionment, filing positions, credits, incentives, and exposure areas, partnering with external advisors to support compliant and efficient state and local tax reporting.
• Develop, maintain, and periodically refresh product and service taxability matrices for sales and use tax, VAT, GST, and other indirect tax purposes, ensuring accurate tax treatment across jurisdictions, customer types, and transaction categories.
• Partner with Commercial, Legal, Operations, Billing, and IT teams to operationalize taxability determinations in ERP, billing, and order-to-cash systems, supporting accurate tax calculation, exemption certificate management, and customer invoicing.
• Identify opportunities to improve tax processes, controls, documentation, and use of systems or data to support scalable, efficient tax operations.

BASIC QUALIFICATIONS:

• Bachelor's degree in Accounting, Tax, Finance, or a related field.
• 8+ years of progressive corporate tax experience, including public accounting and/or corporate tax experience in a multinational environment.

PREFERRED QUALIFICATIONS:

• CPA license and/or Master's degree in Taxation.
• Tax experience in life sciences, biotechnology, diagnostics, or medical technology.
• 4+ years of experience in corporate tax for SEC clients at public accounting or tax advisory firms.
• Strong knowledge of domestic and international tax rules, SALT matters, transfer pricing, tax planning, and tax accounting; experience with Section 382 analyses, R&D credit studies, Article 23 import VAT reporting, or similar specialized matters is a plus.
• Demonstrated analytical, research, and communication capabilities; able to form well-supported tax positions, explain them to leadership, and document them clearly.
• Experience supporting tax compliance and reporting requirements for a publicly traded company, including internal controls, SOX documentation, audit support, and SEC reporting deliverables.
• Demonstrated ability to manage external tax advisors, coordinate deliverables, review technical work product, and meet recurring compliance and reporting deadlines.
• Experience with ERP systems, tax provision or compliance software, indirect tax tools, and advanced Excel-based analysis.

EXPECTATIONS, COMPETENCIES, SKILLS & ABILITIES:

• This role is based in Billerica, MA (hybrid)
  
  • Hybrid employees are expected to work three days per week from our Billerica, MA office, with flexibility on specific days based on business needs and personal commitments.
  
  
  
• Unwavering integrity and a high bar for quality in decision-making, execution, and relationships.
• Strong tax accounting, research, and reporting skills, with the ability to translate complex issues into practical recommendations.
• Proven ability to operate independently, be hands-on, take ownership of complex workstreams, and make sound judgments in ambiguous and fast-paced situations.
• Exceptional written and verbal communication skills, with the ability to clearly document and present tax matters.
• Courage to challenge assumptions, provide counsel to finance leadership, and ask the questions that need to be asked.
• Commitment to staying current on relevant tax developments.

WHY YOU'LL LIKE WORKING WITH US:
Our Technology :
From discovery to diagnostics, Quanterix's ultrasensitive biomarker detection is fueling breakthroughs only made possible through its unparalleled sensitivity and flexibility. Simoa technology has delivered the gold standard for earlier biomarker detection in blood, serum or plasma, with the ability to quantify proteins that are far lower than the Level of Quantification (LoQ). Our industry-leading precision instruments, digital immunoassay technology and CLIA-certified Accelerator laboratory have supported research that advances disease understanding and management in neurology, oncology, immunology, cardiology, and infectious disease.
Akoya Biosciences, a Quanterix company, is The Spatial Biology Company-bringing tissue context to life through high-resolution, single-cell imaging. Akoya's spatial phenotyping platforms help researchers visualize and measure how cells organize and interact within tissue to influence disease progression and therapeutic response. From discovery through clinical research, Akoya offers a full continuum of solutions, including PhenoCycler, PhenoImager Fusion and HT, and PhenoCode Panels. As part of Quanterix, Akoya complements a leading portfolio of ultra-sensitive biomarker detection technologies, together enabling a more complete view of biology and disease across both tissue and blood.
Our Commitment to Employees:
At Quanterix, our values are based on: Team, Innovation, Customer and Owner.

• Team : Challenge assumptions, not the person. Respect diversity of thought and hold ourselves to lofty standards
• Innovation : Stay curious, experiment, create and change
• Customer : Prioritize and celebrate these pioneers by doing our best to deliver on commitments
• Owner : Act with high integrity and in the best interest of Quanterix. Take measured risks and learn from their success and failures.

We reward and recognize our employees by offering competitive compensation and a 401k plan with employer match, as well as competitive health, dental, and vision benefits for employees and their dependents. We also offer an unlimited vacation policy to all exempt employees, and a generous PTO policy for non-exempt employees. All employees are eligible for equity, employee stock purchase plan, a performance bonus, and 1:1 financial counseling/planning. We also offer Tuition Assistance. We have a free, state-of-the-art onsite fitness center for all employees. To keep you fueled up, we provide onsite employees with free snacks and drinks every day!
DIVERSE & INCLUSIVE WORKPLACE:
Quanterix is committed to a Diverse and Inclusive workplace. We strive to recruit candidates who will bring inclusive mindsets and contribute to our values.
Quanterix is an Equal Opportunity Employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status. Quanterix will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.