Clinical Trial Manager/Sr. CTM

Clinical Trial Manager – Janux Therapeutics Join to apply for the Clinical Trial Manager role at Janux Therapeutics . This role is pivotal in executing clinical trials from start‑up to close‑out, managing CROs and study vendors, and ensuring deliverables are on time, within budget, and compliant with regulations. Compensation: $134,000 – $153,000 per year plus equity and a target bonus. Essential Functions and Responsibilities Lead execution of clinical trials from protocol concept to study reports for complex oncology programs. Maintain inspection readiness with comprehensive study documentation and files. Organize and lead study and departmental meetings, including minute‑taking and document archiving. Coordinate equipment, supplies, and cross‑functional project activities. Ensure compliance with study‑specific training and perform TMF reviews. Support sites in audit and inspection preparation. Assist with budget management and daily clinical operations, ensuring SOP, ICH/GCP, and regulatory adherence. Monitor subject and site activity, perform quality checks across study components. Proactively identify and troubleshoot issues impacting deliverables. Contribute to study set‑up activities: protocol/synopsis development, informed consent forms, system configuration (CTMS, IRT), regulatory submissions, and operational documentation. Collaborate with CROs for timely TMF document collection and archiving. Partner with regulatory affairs on essential document submissions. Support study close‑out activities including TMF and drug reconciliation and CSR readiness. Foster effective communication and collaboration with study team members, Clinical Trial Managers, and Asset Leads. Participate in process improvement and quality initiatives related to study execution. Other duties as deemed necessary. Required Education, Experience and Skills Bachelor’s degree with at least 5 years of hands‑on clinical trial experience, preferably in a pharmaceutical or biotech setting. Demonstrated experience in oncology trials, including trial set‑up, monitoring, and close‑out. Global clinical trial management experience, especially in the EU, is highly desirable. Strong working knowledge of ICH/GCP regulations. Proficiency with electronic systems such as eTMF, CTMS, EDC, etc. Ability to work independently and thrive in a collaborative team environment. Strong critical‑thinking skills, sense of urgency, and proactive problem‑solving mindset. Excellent interpersonal, written, and verbal communication skills. Proficiency in MS Office and comfort with technology. Minimal travel required (0–5%). Benefits 401(k) with company match Medical, dental, vision, and supplemental disability insurance Flexible schedule and flexible vacation Life insurance and sick time Incentive stock option plan Relocation assistance Schedule Monday to Friday, full‑time. Work Location On‑site in San Diego, CA. Work Authorization United States (required) Additional Compensation Annual targeted bonus. Equal Opportunity Employer Janux Therapeutics, Inc. is an equal‑opportunity employer committed to providing a work environment free of harassment and discrimination, and free from retaliation for protected activity. Recruiter Notice The Talent Acquisition team manages the recruitment and employment process. Agencies are not permitted to contact Janux employees directly. Unsolicited resumes from agencies are considered referrals without fees. AI Tools Disclosure Janux may use AI tools to support part of the hiring process, but final hiring decisions are made by humans. #J-18808-Ljbffr Janux Therapeutics