Manager, EHS

At RayzeBio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, RayzeBio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact—on our science, on our teams, and most importantly, on patients. Learn more about RayzeBio:

Summary The EHS Manager, reporting to the Director of Health Physics, lead the development, implementation, and continuous improvement of environmental, health, and safety programs for the Indianapolis manufacturing site. This role is responsible for ensuring compliance with applicable federal, state, and local EHS regulations; driving a proactive safety culture; managing risk reduction initiatives; and providing strategic and technical EHS leadership to operations, quality, engineering, facilities, supply chain, and supporting functions. The EHS Manager will also oversee site EHS performance, regulatory readiness, incident prevention, training, emergency preparedness, and environmental compliance programs. Job Responsibilities Essential duties and responsibilities include the following. Other duties may be assigned.

• Lead the development, administration, implementation, and continuous improvement of site EHS policies, procedures, programs, and management systems.
• Ensure compliance with applicable OSHA, EPA, IDEM, IDHS, DOT, NRC/Agreement State, and other federal, state, and local EHS requirements.
• Serve as the site EHS subject matter expert and business partner to Manufacturing, Quality, Engineering, Facilities, Supply Chain, and other cross-functional stakeholders.
• Lead risk assessments, job hazard analyses, industrial hygiene evaluations, ergonomic assessments, safety inspections, and program audits to identify hazards and implement effective controls.
• Own incident, near-miss, injury, spill, and environmental event investigations, including root cause analysis, corrective and preventive actions, effectiveness checks, and communication of lessons learned.
• Develop, deliver, and maintain EHS training programs, including onboarding, annual refresher training, role-specific training, emergency response, hazardous materials handling, PPE, respiratory protection, and contractor safety.
• Manage environmental compliance programs, including hazardous waste, air emissions, wastewater/stormwater, chemical management, SDS systems, and required reporting and recordkeeping.
• Prepare, review, and submit internal and external reports for governmental agencies and corporate stakeholders, including OSHA, EPA, IDEM, IDHS, and other applicable authorities.
• Lead emergency preparedness activities, including emergency action plans, spill response, evacuation drills, fire safety, business continuity coordination, and response equipment readiness.
• Establish and track EHS metrics, trends, corrective action status, audit findings, and performance indicators; communicate results and recommendations to site and functional leadership.
• Support change management, new equipment/process reviews, contractor management, facility modifications, and operational readiness activities to ensure EHS risks are identified and controlled before implementation.
• Promote employee engagement through safety committees, gemba walks, coaching, safety observations, awareness campaigns, and continuous improvement initiatives.
• Up to 10% travel may be required.

Education and Experience

• Bachelor’s degree in Environmental Health and Safety, Occupational Safety, Environmental Science, Engineering, Industrial Hygiene, Chemistry, or a related scientific or technical field required; advanced degree preferred.
• 5+ years of progressive EHS experience in manufacturing, pharmaceutical, biotechnology, radiopharmaceutical, laboratory, or similarly regulated industrial environments.
• Prior experience leading EHS programs, audits, inspections, incident investigations, regulatory reporting, training, and corrective action management required.
• Demonstrated knowledge of environmental, health, and safety regulations and management systems, including OSHA general industry standards, EPA/IDEM environmental requirements, hazardous waste management, industrial hygiene principles, emergency preparedness, and contractor safety.
• Experience in cGMP, pharmaceutical, radiopharmaceutical, chemical manufacturing, laboratory, or highly regulated production environments strongly preferred.
• Professional certification such as CSP, ASP, CIH, CHMM, or equivalent is preferred.
• Supervisory, project leadership, or cross-functional program management experience preferred.

Skills and Qualifications

• Strong leadership presence with the ability to influence across functions, coach employees and leaders, and build a proactive safety culture.
• Excellent knowledge of EHS compliance requirements, risk management practices, incident investigation methods, corrective action systems, and audit readiness expectations.
• Strong analytical, problem-solving, and decision-making skills with the ability to assess complex operational risks and implement practical controls.
• Effective written and verbal communication skills, including the ability to prepare regulatory reports, executive summaries, training materials, SOPs, and site communications.
• Ability to manage multiple priorities, lead cross-functional initiatives, drive accountability, and follow through on commitments in a fast-paced manufacturing environment.
• Proficiency with Microsoft Office and experience with EHS management systems, learning management systems, document control systems, SAP, LabLogic, or other site-specific software platforms preferred.
• Excellent professional ethics, integrity, sound judgment, and ability to maintain confidential information.
• Applies AI to improve team execution and decision‑making

Physical Demands While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 50 pounds. Specific vision abilities required by this job include close vision and distance vision. This is a position that requires working in laboratory and pharmaceutical production environments containing chemical and radiological hazards; protective clothing, gloves, and safety glasses are required while working in these environments. The employee must be able to pass all aspects of respirator fit testing, including medical clearance. Work Environment The noise level in the work environment is usually moderate.

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Compensation Overview:

Indianapolis - RayzeBio - IN: $124,449 - $150,803

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care.

• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).

• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

Work-life benefits include:

Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure: T he summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

RayzeBio and Bristol Myers Squibb

RayzeBio was acquired by Bristol Myers Squibb (BMS) in 2024 and is a wholly-owned subsidiary of BMS; however, RayzeBio will continue to operate as a standalone organization.

Supporting People with Disabilities

BMS and RayzeBio are dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to View email address on click.appcast.io. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS and RayzeBio will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at View email address on click.appcast.io. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response.

R1605561 : Manager, EHS #J-18808-Ljbffr