Associate Director, RDU IT - Business Partner, US Commercial
$124.32k - $163.17kWHY JOIN US?
At Alexion, a division of AstraZeneca, we are driven by a shared purpose to transform the lives of people affected by rare and devastating diseases. By combining deep expertise in rare disease with the scale, science, and innovation of AstraZeneca, we are working to deliver meaningful advances for patients and families with significant unmet needs.
Join us at an exciting time as we continue to evolve how technology, data, digital capabilities, and AI support our Commercial organization. You will have the opportunity to work closely with business and technology leaders, shape solutions that enable new product launches and commercial transformation, and help turn emerging technologies into measurable outcomes for patients and the business.
Our culture is built on collaboration, innovation, and continuous learning. We encourage our people to challenge convention, explore new possibilities, and bring forward ideas that can improve how we work and how we serve patients. As part of Alexion, you will have the opportunity to make an impact in a highly specialized area of healthcare while benefiting from the capabilities and global reach of AstraZeneca.
Hybrid Policy We also recognize the importance of flexibility and balance. Our ways of working support both individual needs and meaningful in-person collaboration. This role is based in Boston, MA, with employees expected to work from the office three days per week , creating opportunities for teams to connect, collaborate, and solve complex challenges together.
Introduction
At Alexion, a division of AstraZeneca, we are dedicated to transforming the lives of patients impacted by rare and devastating diseases. As Director, RDU IT Business Partner, US Commercial, you will serve as a senior business-facing technology partner, shaping and delivering technology, data, digital, and AI-enabled capabilities that support commercial priorities, launch readiness, commercial transformation, and improved patient outcomes.
This position is based in Boston, MA, and may require up to 20% travel.
Position Summary
The Associate Director, RDU IT Business Partner, US Commercial will serve as an IT Business Partner for the US Commercial organization, with a defined portfolio spanning Commercial business functions, Commercial Training, Rare Disease Therapy Area teams, launch, Commercial Operations, Strategic Accounts & Diagnostics and enabling functions and AI-enabled transformation.
This role will build trusted relationships with senior Commercial stakeholders, shape the multi-year technology and AI roadmap for assigned business areas, lead demand prioritization, steward portfolio health, and partner across IT, Digital, Data, AI, Architecture, Cybersecurity, Privacy, Compliance, Finance, Service Delivery, and external partners to deliver measurable business outcomes.
Key Responsibilities
- Serve as an IT Business Partner and trusted advisor for assigned US Commercial business areas, aligning technology, data, digital, and AI roadmaps to business priorities.
- Build and maintain trusted relationships with senior stakeholders across US Commercial, Commercial Training, Rare Disease Therapy Area teams, launch, REMS, Commercial Operations, Strategic Accounts & Diagnostics, and enabling functions.
- Partner with business leaders to translate strategic objectives into capability roadmaps, prioritized demand, investment options, and measurable outcomes.
- Steward assigned Commercial IT portfolio activities, including demand intake, prioritization, funding alignment, risks, dependencies, value realization, ServiceNow visibility, and executive reporting.
- Lead disciplined business capability mapping and technology roadmap development, ensuring roadmaps reflect business strategy, process maturity, data readiness, AI opportunity, and adoption needs.
- Support Market Access and Business Unit priorities at the portfolio level by translating key business needs into scalable, compliant technology and data-enabled solutions.
- Ensure assigned commercial solutions include appropriate governance, compliance, privacy, financial controls, adoption planning, and measurable value outcomes.
- Lead launch technology planning for new products, indications, and therapy area priorities with Sales, Marketing, Commercial Training, Market Access, and business operations.
- Lead through influence across business, IT, data, AI, architecture, delivery, and vendor teams; coach colleagues on business partnering, AI literacy, portfolio governance, executive communication, and value realization.
AI-Ready Business Partner Responsibilities
- Enable AI for the business by identifying, framing, prioritizing, and scaling high-value AI, GenAI, agentic AI, automation, analytics, and data product opportunities across US Commercial workflows.
- Translate AI ideas into business-ready use cases with clear problem statements, target users, data requirements, operating model impacts, success measures, risks, and adoption requirements.
- Drive AI-enabled business outcomes across commercial decision support, launch readiness, Commercial Training enablement, executive reporting, forecasting support, customer engagement, and portfolio prioritization.
- Champion responsible AI adoption by partnering with Data, AI, Architecture, Cybersecurity, Privacy, Legal, Compliance, and business stakeholders to define explainability, traceability, human oversight, auditability, security, and value measurement requirements.
- Move the business from AI experimentation to measurable business impact by defining baselines, success metrics, adoption targets, governance requirements, and continuous improvement loops.
- Model AI-enabled business partnering by using approved AI tools and LLM-enabled workflows to improve stakeholder preparation, meeting synthesis, portfolio reporting, roadmap development, risk identification, executive communication, and follow-through.
- Use AI-assisted analysis to improve demand intake, synthesize stakeholder feedback, compare requirements, identify duplicate or overlapping requests, and generate clearer business problem statements.
- Apply AI to organize knowledge, transition documentation, initiative history, open risks, dependencies, decisions, and stakeholder context while validating outputs and protecting sensitive information.
- Coach business and IT partners with practical, compliant AI usage patterns that improve productivity, quality, decision speed, and accountability.
Essential Qualifications
- Bachelor's degree in computer science, MIS, Business, Life Sciences, Data / Analytics, or related fields.
- 12+ years of experience in IT, digital, data, commercial technology, or enterprise technology roles, including business partnership, portfolio ownership, solution delivery, and cross-functional leadership.
- Experience working in biotech, pharmaceutical, medical device, life sciences, or another regulated industry.
- Demonstrated experience as a senior IT Business Partner or technology leader supporting Commercial, Sales, Marketing, Market Access, Patient Services, Commercial Operations, Finance, or related business functions.
- Strong understanding of US Commercial business processes, launch planning, sales and marketing operations, commercial operations, portfolio governance, and value realization.
- Working knowledge of Market Access, commercial operations, Master Data Management, and related financial decision-support processes.
- Experience shaping or delivering data, analytics, digital, automation, AI, or technology-enabled transformation capabilities.
- Experience with CRM and related commercial platforms such as Salesforce, Veeva, or other life sciences commercial technologies.
- Strong understanding of data products, analytics, reporting, commercial data foundations, SDLC, Agile practices, privacy, security, quality, compliance, and regulatory expectations.
- Experience managing portfolio funding, business cases, risks, dependencies, vendor engagement, and executive-level reporting.
- Ability to influence senior stakeholders, simplify complexity, drive alignment, communicate technology concepts in business language, and connect technology investments to business value, patient impact, efficiency, adoption, and risk reduction.
Preferred Qualifications
- Master’s degree preferred.
- Experience supporting Commercial, Finance, Patient Services, Launch Excellence, Commercial Training, CRM, or Rare Disease Therapy Area technology portfolios.
- Experience with Salesforce Health Cloud, Salesforce Life Sciences Cloud, Veeva, Service Cloud, Experience Cloud, ServiceNow, Snowflake, data products, BI / analytics platforms, or AI-enabled commercial platforms.
- Experience with rare disease commercial models, specialty pharmacy, patient access, payer engagement, field reimbursement, care coordination, or high-touch business-facing environments.
- Experience leading governance forums, executive portfolio reviews, vendor partnerships, product-oriented operating models, transformation programs, adoption plans, and value-realization plans.
- Familiarity with responsible AI principles, including explainability, traceability, human oversight, auditability, privacy, compliance, risk management, and adoption of governance.
- Strong leadership presence with the ability to balance strategic thinking, operational discipline, stakeholder empathy, and execution focus.
SO, WHAT’S NEXT?
To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.
Where can I find out more?
- Explore what we’re building:
- Stay connected and see our impact in action:
Apply today to shape the future of AI-powered rare disease care! Alexion is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. Alexion is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing View email address on careers.astrazeneca.com .
#LI-Hybrid The annual base pay for this position ranges from $124,320.00 - $163,170.00 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.
In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.
Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Date Posted
11-Nov-2026Closing Date
24-Nov-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
$153.02k - $229.53k
Role OverviewAs Director, IT Business Partner - Global Medical Affairs, you will serve... ...in the Rare Disease Unit (RDU). In this strategic role,... ...functional initiatives with Commercial, R&D, and enabling functions... ...form.SummaryLocation: US - Boston - MAType: Full timeCommercialFull timeTemporary work$195k - $225k
...alter the course of lives.The IT Business Relationship Director is the senior technology... .... Salesforce is the key commercial platform for both Epilepsy... ...the role. The Director will partner closely with the... ...address.SummaryLocation: US_Remote; Chicago, Illinois,...CommercialFull timePart timeLocal areaRemote workWorldwide$164k - $225.5k
About This Role:As the Associate Director of Data Science & AI,... ...making across our U.S. Commercial organization.... ...commercial effectiveness.Partner with Commercial, Medical... ...insights into evidence-based business strategies.Communicate... ...and perspectives make us a stronger and more...CommercialFull timeTemporary workLocal area3 days per week$126k - $234k
The Associate Director, Neuromuscular, US Patient Advocacy collaborates with relevant... ...needs that inform business strategy, mobilize... ...of the patient/care partner experience and unmet... ...other stakeholders Commercial launch experience... ...innovative science. It takes a community of...CommercialRemote workRelocationHome office$164k - $225.5k
...patients. We are seeking an Associate Director, US Launch Excellence, Lupus... ...Insights and Analytics, Commercial Operations, IT, HR, etc. Biogen is... ...and readiness reviews. Partner closely with Global and U... ...potential based on individual, business unit and company...CommercialTemporary workLocal area$183k - $252k
About this roleThe Associate Medical Director, Rare Disease role is a... ...Affairs, a strategic partner within Biogen, that helps... ...a key member of the US Rare Disease Medical... ..., Pharmacovigilance, Commercial, Market Access).... ...Understand the local business needs and provide insights...CommercialFull timeTemporary workWork at officeLocal area$183k - $252k
About this roleThe Associate Medical Director, Rare Disease role is a... ...Affairs, a strategic partner within Biogen, that helps... ...a key member of the US Rare Disease Medical... ..., Pharmacovigilance, Commercial, Market Access).... ...Understand the local business needs and provide insights...CommercialFull timeTemporary workWork at officeLocal area$154.4k - $242.55k
...and be empowered to deliver your best. The US Oncology Market Access Analytics Lead... ...actionable insights, and communicate the business impact to cross-functional stakeholders to... ...market access space.How you will contribute:Partner with various US OBU PVA functions to...Minimum wageLocal areaRemote work$180k - $200k
The Associate Director, Commercial Technical Solutions serves as a key bridge between Business Development, Technical Operations, and Commercial Strategy... ...& Technical Solutions Partner with Business Development and... ...processed, please contact us. #J-18808-Ljbffr Landmark BioCommercial$184k - $218k
Associate Director, IT Application Management (Market Access & Patient... ...is an independent, commercial-stage... ...governed model gives us the freedom to invest... ...technology lead and strategic partner for the Market Access... ...intelligence. Working across business, enterprise IT, data...CommercialContract workTemporary workFlexible hours$183k - $252k
## Associate Medical Director, Nephrology - US Medical AffairsApply: Hybrid: Cambridge, MA:... ...Medical Affairs, a strategic partner within Biogen, that... ...Scientific Communications, and Commercial* Develop and implement... ...about healthcare and business opportunities. You keep...CommercialFull timeTemporary work$160k - $240k
...Operational Excellence & Business Analytics Associate DirectorVertex... ...'s external commercial manufacturing network... ....The Associate Director, Operational... ...leadership. The role partners closely with... ...partnering with digital/IT functions on data... ...re ready to join us, browse open...CommercialSummer workRemote workFlexible hours2 days per week$154.4k - $242.55k
...DescriptionAbout the role:The Associate Director, Global and US Pipeline Forecasting Lead... ...in the Oncology Business Unit (OBU) and is responsible... ...leadership to cross-functional partners (e.g., Finance, Supply,... ...the potential impact of commercial strategies are planned...CommercialMinimum wageLocal areaRemote work$128.94k - $193.41k
...Alexion-Rare Disease Unit (RDU) IT. As the Associate Director of RDU IT Communications and Change... ...for RDU IT, aligned with business priorities. Manage... ...diverse media channels. Partner with process owners and leaders... ...In-person working gives us the platform we need to...Hourly payFull timeContract workTemporary workWork at officeFlexible hoursShift work3 days per week$155k - $225k
...company focused on developing and commercializing apitegromab for children and adults... ...of Position The Senior Manager / Associate Director, HCP Marketing (US) will play a key role in the execution... ...work closely cross-functional partners deliver an integrated experience for...Commercial$10k
About This RoleThe Associate Director of Strategy and Operations... ...role in ensuring the US Market Access & Reimbursement... ...on its strategy and business priorities by driving... .... This role will partner closely with cross-functional... ...leaders across Commercial, Franchises, Medical,...CommercialFull timeTemporary workLocal area$235k - $260k
...Associate Director US Legal Affairs and Corporate Counsel Location: Boston, MA, US Do you... ...as a strategic, solution-oriented business partner, building strong stakeholder relationships... ...issues across a broad range of commercial, technology, and healthcare matters....CommercialContract workPrivate practiceFlexible hours- ...to be the reinvention partner of choice for our clients... ...stakeholders. Visit us at accenture.com.... ...transformation initiatives to business outcomes including... ...Strong consulting and commercial acumen, including experience... ...work experience. (If Associate’s Degree, must have...CommercialWork experience placementLive inWork at officeLocal area
$132.5k - $271k
...be the reinvention partner of choice for our... ...25 revenue. Visit us at accenture.com.WHO... ...Senior Manager / Associate Director, you will play a... ...workstreamsTranslate client business and engineering... ..., software, IT, and digital leaders... ...dependencies, and commercial guardrails across...CommercialLive inWork at officeLocal area- ...building an integrated commercial technology, data,... ...services, analytics, and business growth.The Associate Director, Commercial... ...Associate Director partners closely with Commercial... ...the interface to the IT vertical Leader for... ...thinking, allowing us to bring groundbreaking...Commercial3 days per week
- Artis BioSolutions seeks an Associate Director of Commercial Technical Solutions to bridge Business Development, Technical Operations, and Commercial Strategy in Watertown, MA. This role blends scientific expertise with commercial acumen to translate customer needs into...Commercial
$151.08k - $226.62k
...This is what you will do: The Associate Director, US HCP Peer-to-Peer (P2P) Marketing,... ...Rare Neurology, is a member of the commercial U.S. Rare Neurology business unit and reports to the Sr.... ...competitive rare neurology markets, partnering closely with the gMG and NMOSD...CommercialTemporary workWork at officeNight shift$183k - $200k
...Opportunity This role plays an important part in delivering and evolving technology solutions across Commercial and Medical. Reporting to the Director, IT Commercial Business Partner, you’ll partner across Commercial, Medical Affairs, Marketing, Patient Services, IT, and...CommercialLocal areaRemote work1 day per week- ...Description Job Description Associate Director (Data Integration & Commercial Analytics) Duration: 9–12 months... ...looking for someone to serve as a core Business Analyst (AD level) who can... ...and cross‑functional alignment. Partner with technical teams on data mapping...Commercial
- Biogen is seeking an Associate Director of Data Science & AI to lead ML and AI initiatives across the U.S. Commercial function. Collaborate with Insights, EDM, IT, and Medical Affairs to deliver predictive models and analytics that inform strategic decisions. The role requires...Commercial
$168k - $252k
...) Operations and Analytics Associate Director leads sophisticated analyses... ...that inform and drive key business decisions— supporting both... ...questions and inform access and commercial decisionsPlay a key role in the forecasting process, partnering with the GTN team to...CommercialFull timeTemporary workSummer workRemote workFlexible hours2 days per week$175k - $195k
Kiniksa Pharmaceuticals is a commercial‑stage biopharmaceutical... ...of patients who need it most.Reporting to the Senior Director of Digital Marketing,... ...commercial teams and our IT business partners. The successful... ...employment. Please contact us to request accommodation...CommercialWork at office$181.5k - $278.3k
...outcomes.We are seeking an Associate Director, MLOps Lead to join our Machine... ...needs across the business units. Successfully manage... ...-Functional Collaboration: Partner with leaders across machine... ...tools against best-in-class commercial and open-source alternatives...CommercialTemporary workRelocation package$170.4k - $255.6k
Job DescriptionGeneral SummaryThe Associate Director, External Innovation reports into the Executive... ...conducting scientific, clinical and commercial analysis, monitoring company/... ...technology landscaping projects & external business opportunities in the pharmaceutical, biotechnology...CommercialFull timeSummer workRemote workFlexible hours2 days per week- ...including: disease model development, AAV discovery, drug efficacy studies, and more. Position Description We are seeking 2 US BD Managers to lead our commercial expansion in the United States. This role involves technical sales, market development, and customer relationship...Commercial
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Associate Director, RDU IT - Business Partner, US Commercial. Be the first to apply!
- associate director biostatistics Boston, MA
- associate director clinical data management Boston, MA
- associate manager brand marketing Boston, MA
- associate manager digital marketing Boston, MA
- associate director clinical operations Boston, MA
- associate strategy director Boston, MA
- associate clinical manager Boston, MA
- associate director operations Boston, MA
- associate director communications Boston, MA
- associate media director Boston, MA




