Scientist II, Advanced Technology Group

DescriptionAt Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing. We believe our people are at the core of everything we do, and we’re committed to cultivating a culture where every individual feels valued and included. To do this, we strive to integrate belonging, inclusivity, diversity, and equity into every aspect of our organization.Together, we are leading the way towards a healthier and more equitable future.Position SummaryThe Editing Technology and Molecular Biology Team at Editas focus on developing novel gene editing technologies for current and future therapeutic programs and is looking to add highly talented and motivated candidate to help develop precise gene correction and insertion platforms for advancing new therapies. This individual will lead the development of novel gene editing technologies and implement these technologies to treat therapeutic indications with significant unmet medical needs. In addition, they will provide molecular biology and cloning support to Editas’ in vitro and in vivo pre-clinical studies. With a strong background in molecular and cellular biology, this person will work within cross-functional teams including Discovery, Human Genetics and Genomics, Platform Technology, Translational Science in development and commercialization of gene therapy drug products.Key Responsibilities:As the Scientist II, Advanced Technology Group, you will be responsible for:Leverage expertise in molecular biology, cell biology, human genomics to develop novel editing technologies that enable expanded editing capabilities (precision editing, targeted insertion and integration).Lead and develop projects and processes for the successful translation of gene editing technology into clinical development.Work cross-functionally to drive technology and program development. Generate data in a timely manner and within deadlines. Maintain clear and detailed electronic notebook and records, and prepare written data reports and figures, and present research results to other team members.Provide training and mentorship to junior scientists and associates. Additional duties may be assigned if necessary. RequirementsThe ideal candidate will possess:Ph.D. in cell biology, molecular biology, bioengineering, or a related field with a track record of productivity and qualification.2+ years of industry experience in molecular biology or a related field.Prior experience related to gene therapy, gene editing and targeting.Molecular biology expertise including DNA recombineering, vector construction, RNA/DNA isolation and quantification (e.g. qPCR and ddPCR), next generation sequencing, western blotting, immunoprecipitation, ELISA, etc. Cell biology expertise including mammalian cell and tissue culture, transient and stable transduction (e.g. AAV, retroviral vectors) and transfection (e.g. nucleofection, lipofection), fluorescence microscopy, immunostaining, and flow cytometry. Hands-on experience developing in vitro and/or cell-based high throughput assays.Direct experience of in vivo studies with animal models is ideal.Strong critical thinking and problem-solving abilities for independent project design, execution and troubleshooting.Outstanding communication skills, both written and oral, and an ability to work in a team-oriented, multidisciplinary environment. Proven track record of collaborating with cross-functional teams. BenefitsBenefits Summary:Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.If you are a results-focused and collaborative professional with a passion for advancing transformative therapies, we invite you to apply. Join us at the forefront of genetic innovation and be a key contributor to Editas Medicine's mission of redefining healthcare through cutting-edge genetic technologies.Fostering Belonging. Fueling Innovation. Transforming Lives.Job SummaryID: 049097B279Department: Advanced TechnologyType: full time