Pathology Sr. Director

Pathology Senior Director The role is focused on digital pathology to accelerate the execution of computational pathology workflows inclusive of AI/ML model development discovery programs. This role ensures reliable execution of computational pathology workflows, including FAIR data curation, quality control, and analysis activities. It also ensures that imaging data, metadata, annotations, and analysis outputs are fit for purpose for AI development and scientific biologic conviction. The ideal pathologist candidate has experience managing and interpreting pathology datasets and coordinating effectively across diverse stakeholders including pathology laboratory scientists, pathologists, bioinformatics, data science, translational sciences, and therapeutic area teams. In addition, the candidate functions as a project pathologist, supporting the advancement of our pipeline by designing, executing, and interpreting toxicology studies, assessing safety risks, and contributing to project strategy across all phases of R&D and marketed products. As part of the core team within TSRS, the candidate collaborates closely with Toxicology, Study Management, and CRO partners. Key Responsibilities Ensure incoming datasets are delivered according to defined data formats, metadata standards, and project requirements. Translate scientific and model development requirements into structured dataset preparation tasks with pathology scientists and pathologists. Ensure imaging data, annotations, and metadata are suitable for downstream AI/ML model development, validation, and scientific analysis. Execute computational pathology workflows across AI model development and discovery projects for image analysis workflows to generate quantitative readouts supporting discovery and program decision-making within cloud-based data platforms. Identify opportunities to improve data workflows, tooling, and operational processes within computational pathology. Stay informed about emerging data management practices, digital pathology technologies, and AI data standards. Provide pathology expertise to the design and conduct of GLP and non-GLP nonclinical safety studies to enable progression of discovery and development programs to decision points, including pathology peer reviews and report review of integrated toxicology reports for finalization. Serve as a contributing author to pathology sections of regulatory documents such as INDs, NDA/BLAs, IBs, and respond to Health Authority questions. What we expect of you The dynamic professional we seek is a leader with these qualifications. Basic Qualifications DVM and 7 years of pathology or toxicology experience Masters degree and 10 years of pathology or toxicology experience Bachelors degree and 12 years of pathology or toxicology experience Preferred Qualifications DVM, Board Certification in Veterinary Anatomic Pathology (DACVP or comparable credentialing body) and PhD in pathology or toxicology. At least 15 years experience in the pharmaceutical sector as a discovery and toxicologic pathologist and an additional 5 years experience integrating pathology data into bioinformatics efforts in a pharmaceutical environment. Experience in pathology data management within pharmaceutical environments is highly desirable. Demonstrated experience working with large-scale imaging datasets (e.g., whole-slide images) and associated metadata in distributed or cloud environments and analysis outputs. Experience with annotation platforms, digital pathology pipelines, or whole-slide image analysis environments. Familiarity with IHC assay workflows and digital slide scanning. Experience interpreting target discovery pathology and toxicology studies. Strong problem‑solving skills and solution‑oriented mindset, particularly when diagnosing and resolving data quality or workflow issues. What you can expect of us From our competitive benefits to our collaborative culture, we support your professional and personal growth and well-being. The expected annual salary range for this role in the U.S. is posted. Actual salary will vary based on several factors including but not limited to relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a total rewards plan, comprising: A comprehensive employee benefits package, including a retirement and savings plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan. Stock‑based long‑term incentives. Award‑winning time‑off plans. Flexible work models where possible. Equal Opportunity Employer Amgen welcomes applicants from all backgrounds and encourages qualified individuals to apply irrespective of age. In any materials you submit, you may redact or remove age‑identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. #J-18808-Ljbffr BioSpace