Oligonucleotide Scientist II — Synthesis & Scale-Up
Advanced Clinical
Advanced Group seeks a Scientist II to support oligonucleotide discovery, synthesis, purification, characterization, and scale-up. The role collaborates across teams to advance therapeutic candidates and ensure quality with HPLC and MS analyses. The ideal candidate has hands-on oligonucleotide chemistry experience, automation proficiency, and strong communication skills to contribute to design and strategy in a fast-paced setting. #J-18808-Ljbffr Advanced Clinical
- Scientist II (Oligonucleotide Synthesis) South San Francisco, United States | Posted on 09/09/2026 Our client, a world leader in biotechnology and life... ...neuroscience, immunology, and oncology programs. Develop and scale up synthesis of lead oligonucleotide candidates for pre...SuggestedLong term contract
- Dawar Consulting, Inc. is seeking a Scientist II to advance oligonucleotide synthesis in South San Francisco, CA. This long-term contract role offers a $51/... ...workflows, performing analytical characterization, and scaling lead candidates for preclinical studies while...SuggestedLong term contract
- Merck & Co. seeks an Oligonucleotide Scientist II to support RNAi drug discovery with hands-on synthesis, purification, and characterization of oligonucleotide therapeutics. The role is fully on-site in South San Francisco, CA, for a 12-month contract (W2). The candidate...SuggestedContract work
- ...Assistance, Inc., (SGA), is searching for an Oligonucleotide Scientist II for a contract assignment with one of... ...in oligonucleotide discovery and synthesis to support our new oligonucleotide... .... Establish methods for scaled-up synthesis of lead molecules and coordinate...SuggestedContract work
- Job Title : Oligonucleotide Scientist II Working Model : Fully on-site, South San Francisco, CA 94080 Working Days : Monday to Friday Duration... ...-on expertise in oligonucleotide therapeutics discovery, synthesis, and nucleic acid chemistry to support RNAi drug discovery...SuggestedContract workLocal areaImmediate startMonday to Friday
$40 - $49 per hour
...creative, self-motivated, collaborative Scientist-II to join the Nucleic Acid Design and... ...for a candidate with experience in oligonucleotide discovery and synthesis to support our new oligonucleotide... .... . Establish methods for scaled-up synthesis of lead molecules and...- Recombia Biosciences, part of the Lesaffre Group, is seeking a Scientist II in Automated Strain Engineering (AuSE) to drive high-... ...strain construction. You will develop new cloning methodologies, scale them to automated workflows, and collaborate with automation engineers...
- .... This role is within a team of highly experienced scientists and managers who have directly enabled the development... ...We are seeking a highly motivated Senior Scientist II to join the Downstream Development team as a Scale-Up Laboratory Purification Leader. In this role,...Full timeLocal area
$124k - $155k
...Francisco Bay Area, Seattle, and London. About the Role As a Scientist II on Xaira's Genomics Core team within the High Throughput Biology... ...with Automation Engineers to develop, implement, and scale automated library preparation and sequencing workflows. Work...Contract workFor contractorsFor subcontractorWork at officeFlexible hours$124k - $155k
...and London. About the Role We are seeking a highly motivated Scientist II to join our dynamic team at Xaira Therapeutics. In this role,... ...assays to support high throughput screening platform development. Scale high-throughput screening strategies for binder discovery in...Contract workFor contractorsFor subcontractorWork at officeFlexible hours$105k - $168k
...informatics to improve organism engineering, screening, selection, and scale‑up for a wide portfolio of precision fermentation and biomass... ...and experience How You'll Contribute To Our Success As a Scientist II in the Automated Strain Engineering (AuSE) Team, you will...Full timeLocal area$124k - $155k
...and London. About the Role We are seeking a highly motivated Scientist II to join our dynamic team at Xaira Therapeutics. In this role,... ...assays to support high throughput screening platform development. Scale high-throughput screening strategies for binder discovery in...Flexible hours$138k - $172k
Biohub is the first large-scale initiative bringing frontier AI models, massive compute,... ...of curing disease. Our technology powers scientists around the world, translating AI capabilities... ...OpportunityBiohub is seeking a Scientist II to lead the scaling of our imaging and...Relocation package- Nurix is seeking a Senior Scientist, Antibody Conjugation to build and own a new bioconjugation capability. You will develop robust chemistries, transfer workflows to automation, and scale conjugation for in vivo studies. You will partner with medicinal chemistry, analytical...
- AbbVie in South San Francisco is seeking a Scientist I/II to join the Drug Product Development group. You will lead formulation studies and be the HPLC/UPLC technical lead, driving drug product development for biologics and ensuring instrument uptime in a collaborative...
- Xaira Therapeutics is seeking an experienced Scientist II for its Genomics Core to lead high-throughput sequencing workflows on Illumina platforms (MiSeq, NextSeq, NovaSeq). You will design and optimize sequencing strategies for CRISPR-based perturbation studies, single...
- Switch Therapeutics in South San Francisco is seeking a Senior/Principal Scientist to lead bioanalytical characterization of oligonucleotide therapeutics, integrating LC-MS/MS and LC-HRMS with PK/PD interpretation. This hands-on role guides method strategy and mentors junior...Full time
$148.5k - $173.25k
...potential new medicines for patients suffering from diseases of cardiac muscle dysfunction. We are seeking a motivated, hands-on Scientist I/II with both in vivo and in vitro research experience, including work in iPSC-derived cardiomyocytes and other primary cell...$124k - $155k
...building antibody discovery engines that feed AI-driven design at scale. We're looking for an accomplished protein biochemist to own... ...work, you'll help raise the group's level — mentoring associate scientists, setting technical standards, and partnering with computational...Flexible hours- Planet Pharma is seeking a PhD-level fermentation scientist to design, execute, and optimize E. coli fermentation processes from benchtop to pilot scale. You will drive improvements to yield and scalability, and prepare clear experimental plans and reports for potential...
- ...Purpose Job Description AbbVies CAR-T Biology team in South San Francisco, part of the Immuno-Oncology Organization, is seeking a Scientist II to support the development of in vivo CAR-T platforms from concept through preclinical development. You will work at the...Temporary workLocal area
- ...HPLC methods for throughput and robustness; establish plate-based sample preparation workflows that maintain data quality at screening scale Present findings to project and platform teams; collaborate with conjugation chemistry, bioanalytical, and cell screening groups to...
$105.28k - $150.4k
Job Description Scientist II, Antibody Engineering Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology...Work at officeWork from homeWorldwide- Xaira Therapeutics in South San Francisco is seeking a Scientist II to lead cutting-edge experiments using functional genomics and synthetic biology to accelerate drug discovery. You will develop high-throughput screens, optimize automated workflows, and collaborate with...
$84.5k - $162k
Scientist II, Biologics Drug Product Development Full-time Salary Min: 84500 Salary Max: 162000 Workday Global Grade: 16 Compensation: USD 84500 - USD 162000 - yearly About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve...Full timeTemporary workLocal area- Xaira Therapeutics in the San Francisco Bay Area is seeking a Scientist II to spearhead design and execution of cutting-edge experiments to accelerate drug discovery using functional genomics and synthetic biology. You will develop high-throughput screens, partner with...
$120k - $150k
...Development ABOUT THE JOB This is a full-time role requiring onsite presence, Monday - Friday in our South San Francisco, CA office. The Scientist II, Discovery Biology is an experienced, hands-on discovery scientist who leads key experimental workstreams supporting the...Full timeContract workWork at officeMonday to Friday$167.88k - $178.5k
...us at . Follow @abbvie on X , Facebook , Instagram , YouTube , LinkedIn and Tik Tok . Job Description Senior Scientist II – CMC Developmental Sciences, AbbVie Biotherapeutics Inc., South San Francisco, CA (100% onsite). Key Responsibilities • Perform...Full timeTemporary workWork experience placement- ...innovative therapeutic biologic products. We are a world-class team of scientists and leaders united by a shared mission to advance industry-... ...We are seeking an experienced and highly motivated Scientist II to join our Quality Control team focused on early stage (first in...Full timeTemporary workLocal areaFlexible hours
- ...eventual licensure. This role is within a team of highly experienced scientists and managers who have directly enabled the development/IND... .... Responsibilities Develop, optimize, characterize, and scale up purification processes for monoclonal antibodies, multispecifics...Full timeContract workLocal area
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