Sr. Scientist - Mass Spec Development (LC-MS/MS)

Job Description

Job Description

Performing critical work that impacts our industry and our world’s health while problem solving and innovating in the field – that is what Sr. Scientists at KCAS Bio get to do every day. If that gets you excited too, then maybe working as a Sr. Scientist at KCAS Bio is the role for you.

When you work as a Sr Scientist in the Mass Spec Bioanalysis Development group at KCAS, you get to further our mission by leveraging your knowledge in bioanalytical and scientific principles to be responsible for carrying out all aspects of a study, from study setup through reporting, as well as development. You will also use your strong foundation in scientific principles/theories to assess data integrity and troubleshoot as needed.

Our Mass Spec Bioanalysis Development team uses LCMS (Liquid Chromatography Mass Spectrometry) techniques to conduct sophisticated sample preparation to meet bioanalytical needs for drug discovery, preclinical, and clinical studies, including bioanalysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues.

In this role, we will rely on you to:

• Design and execute all phases of assigned projects, including sample preparation (extractions, enrichments/affinity capture, digestions), method development and qualification for LCMS, troubleshooting, data analysis, and report generation
• Act as lead scientist, help to design experiments, provide work instructions, and technical training to more junior scientific staff in daily activities
• Be responsible for all client communication related to study conduct
• Be responsible for timeline adherence and communication of status to management as required
• Ensure compliance of study activities with pertinent portion of study protocol, SOPs & any additional requirements
• Be able to set up and change instrument configurations for various LCMS methods
• Prepare and present data summaries for client updates
• Act as a technical expert for all aspects of process design and problem-solving
• Perform all aspects of the job in a way that supports the company brand and supports the company mission, vision, and values

To qualify specifically for this role, you will have:

• Bachelor’s, Master’s, or PhD in Chemistry, Biochemistry or chemical/biochemical engineering, or related field with at least 5 years of experience with LC-MS/MS
• 2-3 years of experience overseeing projects
• Bioanalytical sample preparation, Quantitative LC-MS/MS, and multi-dimensional chromatography
• Experience with proteins and peptides as well as small molecule biomarkers is preferred
• Experience with Reversed Phase and Hilic chromatography at the analytical and micro/nano flow rates or protein digestions and immunoaffinity enrichments (hybrid LCMS) is a plus

(Please note this is a representative summary of responsibilities, not a comprehensive or exclusive list of the duties to be performed in any position. Employees must follow instructions and perform additional duties as requested.)

 

WHO YOU ARE

You will thrive at KCAS Bio if you enjoy a relational environment, are purpose- and values-driven, embrace constant development and supportive leadership, and enjoy being part of innovative work.

 

WHAT YOU’LL GET

Our benefits include, and extend beyond, the traditional package. At KCAS Bio, you will enjoy company sponsored events like food trucks, family days and spirit days. You will grow in your career with KCAS University. You will be able to connect with like-minded employees to further KCAS Bio's approach to key areas such as wellness, inclusion, and community outreach. You will engage as an owner in our stock ownership program. You will have access to the latest technology. And you will be able to invest in the community with paid time off to volunteer.

 

Learn more about the Benefits at KCAS Bio 

 

WHO WE ARE

We are a fast-growing contract research organization (CRO) headquartered in Kansas City, pioneering the latest drug development in both human and animal health fields. Demand for our expertise is growing and so is our need for great people to work in nimble, empowered teams committed to one another’s growth. At KCAS Bio, we advance both great science AND great people.

 

Learn more about what it is like to work at KCAS Bio

 

KCAS Bio is proud to be an Equal Opportunity Employer. Among other things, we provide equal employment opportunities without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, sex, sexual orientation, gender identity, or any other legally protected category; we recruit qualified candidates without regard to citizenship status based on internal processes that enable us to hire the right candidates consistent with the appropriate U.S. Immigration framework; and (3) we work with and provide reasonable accommodations to individuals with disabilities and for sincerely held religious beliefs, observances, and practices. Anyone who needs reasonable accommodation may send an email to View email address on us.fitly.work or call View phone number on us.fitly.work (for TTY assistance call 711) and ask for Human Resources.

 

IND123

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.