Scientist I

Piper Companies is seeking a Scientist I to join a growing pharmaceutical organization in Greenville, SC . The Scientist I will be heavily focused on analytical sample preparation, extraction techniques, and method validation activities supporting raw material and finished product testing in a cGMP-regulated lab. This role is centered around complex sample matrices, HPLC analysis, validation documentation, and pharmaceutical lab compliance. Responsibilities of the Scientist I: Perform hands‑on analytical sample preparation and extraction of target analytes from complex raw material and finished-product matrices utilizing dilution, filtration, centrifugation, and multi‑step extraction techniques. Evaluate extraction efficiency, sample recovery, dilution requirements, and matrix interference while supporting method verification and validation studies. Author, execute, and summarize method verification and validation protocols and reports in accordance with USP , USP , and ICH Q2(R2) guidelines. Conduct HPLC analysis utilizing Empower chromatography software to generate, review, and report analytical data while troubleshooting sample preparation and analytical issues. Maintain complete cGMP documentation including lab notebooks, data review, protocol execution, and adherence to approved SOPs and data integrity requirements. Support analytical testing of raw materials, in‑process samples, and finished products while participating in method transfers and lab investigations as needed. Qualifications of the Scientist I: BS or MS in Chemistry or related scientific discipline with 4+ years of pharmaceutical laboratory experience. Extensive hands‑on experience with analytical sample preparation, extraction procedures, recovery studies, and troubleshooting matrix‑related analytical challenges. Proven experience performing and documenting method verifications, method validations, and method transfers within a cGMP environment. Advanced proficiency with HPLC chromatography and Empower software; experience with Agilent HPLC systems is preferred. Strong understanding of FDA‑regulated laboratory operations, cGMP requirements, and data integrity principles. Comprehensive knowledge of USP , USP , ICH Q2(R2), and pharmaceutical analytical testing requirements. Compensation for the Scientist I includes: Compensation Depending on Experience Comprehensive benefits package including medical, dental, vision, and retirement plans Around 6 Month Contract This job opens for applications on 10/07/2026. Applications for this job will be accepted for at least 30 days from the posting date. SEO Keywords Scientist I, Analytical Chemist, QC Scientist, Pharmaceutical Scientist, Validation Scientist, Method Validation, Method Verification, Method Transfer, Sample Preparation, Sample Extraction, Analytical Chemistry, HPLC, Agilent HPLC, Empower Software, Empower CDS, Recovery Studies, Matrix Interference, Raw Material Testing, Finished Product Testing, cGMP Laboratory, GMP Documentation, USP 1225, USP 1226, ICH Q2R2, Pharmaceutical Quality Control, Laboratory Compliance, Chromatography, Pharmaceutical Testing, Greenville SC Jobs, Chemistry Jobs

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