Principal Data Architect II - Biotherapeutics and Genetic Medicine
Allergan
Position Overview Biotherapeutics and Genetic Medicine (BGM) sits within AbbVie’s Discovery Research organization and supports discovery and optimization across biotherapeutic and genetic medicine modalities, including monoclonal antibodies, multispecifics, proteins, conjugates, AAV, LNPs, and siRNA. The Principal Data Architect will shape the cloud-native data foundation that enables predictive and generative AI/ML solutions in discovery scientist workflows. This role owns the architecture, adoption, and continuous improvement of a scalable data platform that connects laboratory data across dozens of assays, supports machine learning development and deployment, and improves how scientific data is used across the organization. The position reports to the Head of AI/ML in BGM and serves as a trusted advisor to senior leadership. This is a technical leadership role on the individual contributor track, with potential to expand into people management in the future. It requires close partnership with wet lab scientists, ML engineers, software engineers, data engineers, automation teams, and data governance partners. The role is central to building a robust, resilient, and scalable data foundation for BGM’s AI/ML strategy. Responsibilities Define and drive the architecture for a scalable, cloud-native data platform that supports AbbVie’s AI/ML strategy in BGM. Design data models and integration patterns that connect datasets generated across multiple lab groups and establish certified datasets for downstream scientific, operational, and machine learning use. Partner with wet lab scientists and automation engineers to maximize the value of data captured through lab automation workflows. Work with data scientists and deployment engineers to ensure data pipelines support both model development and production deployment. Advance FAIR data practices and data stewardship in alignment with BGM strategic priorities. Champion connected data, data-as-a-product, and cloud-first architecture principles across the organization. Partner with data infrastructure and governance experts to ensure data policies are implemented effectively. Align BGM data infrastructure initiatives with broader AbbVie efforts such as Convergence and ARCH. Communicate platform impact through user stories, metrics, and KPIs that show the value of the data platform to AbbVie’s therapeutic program pipeline. Qualifications MS with 14+ years’ or PhD with 8+ years’ experience in machine learning, computer science, applied mathematics, data science, computational biology, or a closely related field. 6+ years of experience in data architecture after completion of graduate studies, with a track record of designing enterprise data platforms. Graduate degree in computer science, data science, computational biology, computational chemistry, computational biophysics, or a related field. Experience designing enterprise data platforms. Strong technical skills in data modeling, data integration, data storage solutions, data pipelines, and AI/ML integration. Production programming experience in SQL, Python, or Java. Experience building cloud data infrastructure on AWS, Azure, or GCP. Ability to work across wet lab and dry lab scientific workflows. Experience collaborating across functions and building stakeholder alignment. Strong communication and interpersonal skills. Ability to apply data governance principles in day-to-day decision-making. Experience in the pharmaceutical or biotechnology industry. Preferred Experience leading cross‑functional technical teams across reporting lines and multiplying their impact through best practices. Experience working in large, cross‑functional R&D environments. Work Environment Hybrid role based in Worcester, MA, South San Francisco, CA, or Cambridge, MA. On‑site presence required 3 days per week. Relocation is available. This is an individual contributor role. Additional Information The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our long‑term incentive programs. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: #J-18808-Ljbffr
- ...discover and deliver innovative medicines and solutions that solve... ...Description Discovery Biotherapeutics and Genetic Medicine (BGM) at AbbVie is... ...seeking a highly motivated Principal Scientist to join the... ...complex datasets to drive data-based decisions. CRO and...PrincipalTemporary workLocal area
$120k - $147k
Senior Research Associate II, Medicinal Chemistry Apply for the Senior Research Associate II,... ...biopharmaceutical company harnessing the power of human genetics to develop novel, small‑molecule... ...benchmarking to industry market data to ensure we pay competitive wages. Determination...SuggestedFull time- ...Job Description Job Description Principal Scientist / Senior Scientist, Analytical... ...next-generation delivery platform for genetic medicines. Our team integrates chemistry, payload... ...creative problem-solving and high-impact data drive decisions. The Role We are...Principal
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$196k - $242k
...Biosciences IDEAYA is a precision medicine oncology company committed to... ...therapies aligned to the genetic drivers of disease. We have... ...seeking an accomplished Senior Principal Research Scientist in... ..., scripting, statistics, and data analysis experience applied to...PrincipalTemporary workLocal areaRemote work1 day per week$196k - $242k
...IDEAYA Biosciences is a precision medicine oncology company committed to... ...therapies aligned to the genetic drivers of disease. We have... ...seeking an accomplished Senior Principal Research Scientist in... ..., scripting, statistics, and data analysis experience applied to...PrincipalTemporary workWork at officeLocal areaWork from home$150.7k - $279.9k
...Genentech’s Department of Human Genetics sits at the center of our precision medicine strategy, combining large-scale genetic... ..., cellular, and clinical data to uncover causal disease biology... ...strategies. Opportunity We are seeking a Principal Scientist (Bioinformatics track)...PrincipalLocal areaRelocation package$360k
...Sr. Principal / Distinguished ML Scientist, Autonomous Science... ...the hardest problems in medicine. Within Life Science AI... ...profiling, imaging, genetics, and multi-modal experimental data that integrate deep biological... ...‑science platform. Architect how cell‑biology research...PrincipalFull timeWork at officeLocal areaFlexible hours$202.5k - $236.25k
...advancing a pipeline of potential new medicines for patients suffering from... ...seeking a highly motivated and skilled Principal Scientist, Translational Genetics to join our growing team. The successful... ...applications. Responsibilities: Data Analysis: Perform genome-wide...PrincipalFull time- MSD Malaysia is seeking an Associate Principal Scientist in South San Francisco to lead in vivo pharmacology strategy within its Quantitative Biosciences department. The successful candidate will leverage their expertise in cardiometabolic, renal, or respiratory disorders...Principal
- ...transformation, we are establishing a modern enterprise data foundation powered by Databricks to unify data across engineering... ..., finance and commercial systems. We are seeking a Principal Enterprise Data Architect, a highly hands-on individual contributor who will design...PrincipalFlexible hours
- ...Initial Therapeutics, Inc. is seeking a Principal Scientist in Computational Biology & Translational AI focused on oncology precision medicine. This role integrates preclinical and clinical data using AI systems to drive insights and inform development strategies. Candidates...Principal
- ...biotech company in California is seeking a Principal Scientist specializing in Computational Biology... ...role focuses on integrating multi-modal data to drive forward and reverse translation insights in oncology precision medicine. Ideal candidates will have a PhD in...Principal
$150.7k - $279.9k
...F. Hoffmann-La Roche AG is looking for a Principal Scientist to contribute to innovative research in statistical genetics and AI/ML. This role is critical in Neuroscience target... ...cutting-edge analyses across diverse genomics data. The ideal candidate will have a PhD and...Principal$204.5k - $267k
...Principal Data Scientist, Medical Imaging New York, NY; Boston, MA About Formation Bio... ...may ultimately limit the number of new medicines that can reach patients, Formation Bio,... ..., sexual orientation, age, disability, genetic information, marital status, military or...PrincipalWork at officeLocal areaRelocation3 days per week$71.25k - $187k
...work to discover and bring life‑changing medicines to those who need them, improve the understanding... ..., interpret, and present experimental data. Adhere to good research practices and... ..., gender expression, sexual orientation, genetic information, ancestry, national origin,...PrincipalFull timeH1bWorldwideFlexible hours$170.2k - $316k
...strategic, unified group whose goal is to harness the power of data and Artificial Intelligence (AI) to assist scientists in both pRED and gRED to deliver innovative medicines worldwide. This Senior Principal Product Leader reports to the Domain Head for Therapeutics...PrincipalWorldwideRelocation package$187.8k - $234.8k
...Job Description Job Description Principal Clinical Scientist, ECD About the Role We... ...central to driving study design, clinical data review, and scientific insights across multiple... ...health. Our aim is to make personalized genetic testing and diagnostics part of the...PrincipalWork at officeImmediate startRemote workWorldwide- ...Kaiser Permanente is seeking a Registered Nurse II in San Francisco, CA, who will be responsible for caring for patients and collaborating with other health care team members. The ideal candidate will have a solid background in acute care, hold a valid California RN license...
$226.67k - $236.26k
...A national insurance group is seeking a Principal Data Architect to shape the enterprise data architecture and support their strategic transition toward AI adoption. The ideal candidate will lead efforts in data integration, real-time analytics, and the establishment...Principal- ...AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and... ...laboratory work to ensure quality and on-time execution. Interpret data trends across release, stability, and characterization assays....PrincipalFull timeContract workLocal areaFlexible hours
- ...childbirth, breastfeeding and/or related medical conditions, age, national origin, ancestry, citizenship, disability, medical condition, genetic information or condition, status as a special disabled veteran, veteran of the Vietnam era, or other eligible veteran, sexual...
- ...cellular biology techniques to study signaling pathways, protein trafficking, immune-related responses, and genetic interactions Analyze and interpret experimental data with a focus on accuracy, reproducibility, and mechanistic understanding Collaborate closely with...Principal
$85k
...A Day in the Life As a Principal Territory Manager for Coronary... ...healthcare leaders by delivering data-driven, customer-focused... ...identity and/or expression, genetic information, marital status,... ...one another, we use science, medicine, and a profound understanding...PrincipalContract workH1bWork at officeLocal areaRemote workFlexible hoursShift workNight shift$109.5k
...discover and deliver innovative medicines and solutions that solve... ...with internal clients to provide?data management and decision support... ...team, the?Senior?Data Scientist II will support projects in... ...internal IT disciplines (DBAs, architects, developers, etc.) and external...Local area$161.93k - $227.33k
...we are seeking a Senior Software Engineer II to join our innovative Engineering team. The... .... Contribute to the development of data infrastructure for machine learning applications... ...disability, medical condition, pregnancy, genetic information, gender, sexual orientation,...Work experience placementLocal areaRemote work$140k - $150k
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$159k - $207k
...commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists,... ...generate late-stage process characterization and/or validation data packagesSupport selection/coordination of CDMOs as needed to generate...PrincipalContract workWork experience placementLocal area- ...research and development. - Guide and mentor architects and engineers establishing and... ...approaches for architecture of enterprise data solutions. - Optimize overall data/information... ...origin, disability, veteran status, genetic information and other legally protected characteristics...PrincipalMinimum wageContract workTemporary workWork experience placementLocal areaRemote work
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