Principal Data Architect II - Biotherapeutics and Genetic Medicine
Allergan
Position Overview Biotherapeutics and Genetic Medicine (BGM) sits within AbbVie’s Discovery Research organization and supports discovery and optimization across biotherapeutic and genetic medicine modalities, including monoclonal antibodies, multispecifics, proteins, conjugates, AAV, LNPs, and siRNA. The Principal Data Architect will shape the cloud-native data foundation that enables predictive and generative AI/ML solutions in discovery scientist workflows. This role owns the architecture, adoption, and continuous improvement of a scalable data platform that connects laboratory data across dozens of assays, supports machine learning development and deployment, and improves how scientific data is used across the organization. The position reports to the Head of AI/ML in BGM and serves as a trusted advisor to senior leadership. This is a technical leadership role on the individual contributor track, with potential to expand into people management in the future. It requires close partnership with wet lab scientists, ML engineers, software engineers, data engineers, automation teams, and data governance partners. The role is central to building a robust, resilient, and scalable data foundation for BGM’s AI/ML strategy. Responsibilities Define and drive the architecture for a scalable, cloud-native data platform that supports AbbVie’s AI/ML strategy in BGM. Design data models and integration patterns that connect datasets generated across multiple lab groups and establish certified datasets for downstream scientific, operational, and machine learning use. Partner with wet lab scientists and automation engineers to maximize the value of data captured through lab automation workflows. Work with data scientists and deployment engineers to ensure data pipelines support both model development and production deployment. Advance FAIR data practices and data stewardship in alignment with BGM strategic priorities. Champion connected data, data-as-a-product, and cloud-first architecture principles across the organization. Partner with data infrastructure and governance experts to ensure data policies are implemented effectively. Align BGM data infrastructure initiatives with broader AbbVie efforts such as Convergence and ARCH. Communicate platform impact through user stories, metrics, and KPIs that show the value of the data platform to AbbVie’s therapeutic program pipeline. Qualifications MS with 14+ years’ or PhD with 8+ years’ experience in machine learning, computer science, applied mathematics, data science, computational biology, or a closely related field. 6+ years of experience in data architecture after completion of graduate studies, with a track record of designing enterprise data platforms. Graduate degree in computer science, data science, computational biology, computational chemistry, computational biophysics, or a related field. Experience designing enterprise data platforms. Strong technical skills in data modeling, data integration, data storage solutions, data pipelines, and AI/ML integration. Production programming experience in SQL, Python, or Java. Experience building cloud data infrastructure on AWS, Azure, or GCP. Ability to work across wet lab and dry lab scientific workflows. Experience collaborating across functions and building stakeholder alignment. Strong communication and interpersonal skills. Ability to apply data governance principles in day-to-day decision-making. Experience in the pharmaceutical or biotechnology industry. Preferred Experience leading cross‑functional technical teams across reporting lines and multiplying their impact through best practices. Experience working in large, cross‑functional R&D environments. Work Environment Hybrid role based in Worcester, MA, South San Francisco, CA, or Cambridge, MA. On‑site presence required 3 days per week. Relocation is available. This is an individual contributor role. Additional Information The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our long‑term incentive programs. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: #J-18808-Ljbffr
- ...Position Overview The Principal Machine Learning Scientist II will advance deep learning methods for biologics... ...to support the complexities of biotherapeutics, including complex multispecific formats... ...science, applied mathematics, data science, computational biology, or...PrincipalWork at officeLocal areaRelocation3 days per week
- ...Allergan is seeking a Principal Data Architect to lead the development of a scalable, cloud-native data platform aimed at enhancing predictive and generative AI/ML capabilities for discovery workflows. Candidates should possess an MS with 14+ years or PhD with 8+ years...Principal3 days per week
$164.44k - $236.5k
...discover and deliver innovative medicines and solutions that solve... ...Responsibilities Function as a principal investigator, generating... ...nonconventional oral delivery systems; (ii) managing clinical supply... ..., medical condition, genetic information, gender identity...PrincipalTemporary workWork experience placement- ...discover and deliver innovative medicines and solutions that solve... ...functional teams with Discovery Biotherapeutics, DMPK, and Development... ...interpret multidisciplinary data to generate actionable conclusions... ...CNS-relevant biology and genetic medicine applications...SuggestedLocal area
$188k - $282k
...individual with a passion for data and AI technology who can... ...on the forefront of science, medicine, and technology. As part of this... ...adoption at scale.As a Senior Principal AI Engineer in the Data... ...disability, veteran status, genetic information, sexual orientation...PrincipalSummer work$128.6k - $210k
...Regeneron’s Precision Medicine Quantitative Biomarker... ...(PMQBS) is seeking a Principal Scientist with a blend... ..., and other biomarker data. The position is also... ...development and asset strategy. Architect exploratory analyses... ..., disability, genetic information, familial...Principal$170k - $230k
...Associate Principal Scientist, PharmaR&D at Tempus –... ...Passionate about precision medicine and advancing the... ...clinical and genomic data. Analyze and integrate... ...interactions with clients to co‑architect solutions and projects... .../Statistical Genetics, Bioinformatics, Biomedical...PrincipalShift work$142.5k - $256.5k
...antigens and explore new concepts for mRNA medicines.**Here’s What You’ll Do*** Lead... ...judgment, and ownership consistent with a Principal Scientist role.**Here’s What You’ll Bring... ..., military or protected veteran status, genetic information, sexual orientation, marital...PrincipalWork at officeWork from home- ...unique machine learning challenges to advance medicine and improve patient care. You will work closely with teams across biomedical data science, product development, translational... ...models, and learn best practices. MLE II : Independently deliver on projects, improve...Hourly pay
$174.8k - $262.2k
General Summary The Principal Biostatistician will perform advanced... ...support of the company's Global Medicines Development and Affairs area... ...studies, or real world data investigations, including the... ...disability, veteran status, genetic information, sexual orientation...PrincipalSummer workRemote workFlexible hours2 days per week$204.5k - $267k
...Principal Data Scientist New York, NY; Boston, MA About Formation Bio Formation Bio... ...may ultimately limit the number of new medicines that can reach patients, Formation Bio,... ..., sexual orientation, age, disability, genetic information, marital status, military or...PrincipalWork at officeLocal areaRelocation3 days per week- ...Allergan is seeking a Principal Machine Learning Scientist II based in Cambridge, MA to advance deep learning methods for biologics discovery and therapeutic antibody design. This role involves collaborating with antibody engineers and computational biologists, focusing...Principal
$142.5k - $256.5k
...Principal Scientist, Computational Protein Design page is loaded##... ...explore new concepts for mRNA medicines.**Here’s What You’ll Do*** Serve... ...teams by interpreting data from in vitro selection and screening... ...or protected veteran status, genetic information, sexual...PrincipalPermanent employmentWork at officeWork from home$111.38k - $185.63k
...Principal Scientist, Oligonucleotide Analytical ChemistryAt GSK, we... ...and delivering vaccines and medicines, combining our understanding... ...settingsHelp design and manage key data pipelinesCollaborate... ...national origin, age, disability, genetic information (including family...PrincipalLocal area$148k - $222k
...seeking a dedicatedPrincipal Data Engineerwith a passion forpharmaceutical... ...on the forefront of science, medicine, and technology. As part of... ...management - Estimate, architect, and execute ondelivery... ...disability, veteran status, genetic information, sexual orientation...PrincipalSummer workWork at officeRemote workFlexible hours2 days per week$204.5k - $267k
...Principal Data Scientist, Medical Imaging New York, NY; Boston, MA About Formation Bio... ...may ultimately limit the number of new medicines that can reach patients, Formation Bio,... ..., sexual orientation, age, disability, genetic information, marital status, military or...PrincipalWork at officeLocal areaRelocation3 days per week- Principal Scientist, Neurology Research, Cambridge MA Location: Cambridge... ...scale public and internal data sets from human brain tissue... ...- enables us to invent medicines and vaccines that treat and protect... ...cellular or blood trait; genetic information (including the refusal...PrincipalShift work
$115.5k - $192.5k
...and delivering vaccines and medicines, combining our understanding... ...disease‑related initiatives. As a Principal Scientist, you will provide... ...to ensure protein reagents, data, and workflows are aligned with... ...origin, age, disability, genetic information (including family...PrincipalLocal area$110k - $125k
...Job Description Job Description Principal Associate Scientist, Discovery & Translational... ...MA Solid Biosciences is a precision genetic medicine company focused on advancing a... ...experimental procedures, materials, reagents, and data Data Analysis: Independently analyze...PrincipalTemporary workWork at officeFlexible hoursShift work- ...a clinical-stage biotechnology company developing innovative genetic medicines based on RNAi (RNA interference) technology. Powered by the proprietary... .... Analyze the SAR (Structure-Activity Relationships) data, formulate the hypothesis, and guide the optimization. Design...Principal
- ...A leading healthcare provider in Boston seeks a Medical Laboratory Scientist II to perform laboratory testing under supervision. Responsibilities include managing quality control, supervising personnel, and maintaining accurate records. The role requires a Bachelor's...
- ...Boston Medical Center in Boston is seeking a Medical Technologist II responsible for performing moderate and high complexity clinical laboratory tests. Candidates should have a relevant bachelor's degree and required experience in laboratory settings. The role involves...
- ...childbirth, breastfeeding and/or related medical conditions, age, national origin, ancestry, citizenship, disability, medical condition, genetic information or condition, status as a special disabled veteran, veteran of the Vietnam era, or other eligible veteran, sexual...
$142.8k - $214.2k
...innovation to create transformative medicines for people with serious... ...-driven environment. The Principal Analyst - CGT Process Automation... ...the Commercial CGT DTE (Data, Technology & Engineering) team... ...disability, veteran status, genetic information, sexual orientation...PrincipalSummer workRemote workWorldwideFlexible hours2 days per week$140k - $220k
...With programs like Future of Medicine , which makes advanced... ...seeking a highly experienced Principal Trainer, Clinical Education,... ...metrics, audit trends, and CAPA data. Lead the continuous improvement... ...origin, disability status, genetic information, protected...PrincipalFull timeTemporary workWork at officeLocal areaRemote workWorldwideVisa sponsorshipWork visaFlexible hours$95.3k - $158.8k
...clinical and content workflows. You will bridge Data Science and Engineering to turn... ...domains, including science, technology, medicine, social sciences, and more. They publish... ...status, sexual orientation, gender identity, genetic information, or any other characteristic...Local area- ...generation therapeutics. We are seeking a Principal Scientist to join our Biologics Cell... ...Boston, MA and help push the boundaries of biotherapeutic cell line development. This role is for... ...through the development of improved genetic components, host cell line engineering...Principal
- ...Merck & Co. is seeking a Senior Principal Scientist (Senior Medical Director) to lead translational medicine initiatives in Boston, MA. This role requires a seasoned physician-scientist with extensive experience in clinical research and immunology. Responsibilities include...Principal
$30.05 - $43.75 per hour
...Boston Medical Center is looking for a part-time Medical Technologist II to provide support in clinical laboratory activities, including performing complex tests and ensuring regulatory compliance. The role requires a Bachelor's degree in Medical Technology or a related...Hourly payDaily paidPart time$156.64k
...Maximus is currently seeking an IT Principal Data Architect. The IT Principal Data Architect - (Data Migration) is a senior technical leader responsible... ..., sex, age, national origin, disability, veteran status, genetic information and other legally protected characteristics....PrincipalLocal areaRemote work
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