Principal Clinical Scientist

Principal Clinical Scientist (AI Training) What if your career-long expertise in clinical trial design and regulatory science could directly influence how AI reasons about medicine, data, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to one of the most consequential challenges in AI development: ensuring that AI systems trained on clinical data actually understand it the way regulators, researchers, and clinicians do. This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the frontier of AI and biomedical research — on their own terms. Organization: Alignerr Type: Hourly Contract Location: Remote Commitment: 10–40 hours/week What You'll Do Design and critically review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training Interpret and audit clinical trial results for accuracy, consistency, and alignment with regulatory standards Evaluate AI-generated clinical analyses for scientific soundness and compliance with FDA, EMA, or equivalent agency expectations Provide expert, structured feedback that directly improves how AI models reason about clinical evidence, trial methodology, and outcomes Flag gaps, inconsistencies, or methodological errors in AI-generated clinical content Work independently and asynchronously — fully on your own schedule Who You Are Senior-level experience designing clinical trial protocols for regulatory submission — you've done this at a high level in the real world Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies Strong grounding in clinical research methodology, biostatistics, or translational science Naturally rigorous and detail-oriented — you hold AI-generated content to the same standards you'd apply to a real submission Clear and precise written communicator who can articulate complex scientific reasoning in structured feedback Nice to Have Prior experience with data annotation, data quality assurance, or evaluation systems Background in regulatory affairs, clinical operations, or medical writing Familiarity with AI tools or scientific evaluation workflows Experience working across therapeutic areas or with international regulatory submissions Why Join Us Work directly on frontier AI systems that are reshaping clinical and biomedical research Influence how AI understands, evaluates, and reasons about real-world clinical evidence — at scale Fully remote and flexible — work when and where it suits you Freelance autonomy with the structure of meaningful, high-impact work Collaborate with world-leading AI research teams and labs Potential for ongoing work and contract extension as new projects launch #J-18808-Ljbffr Alignerr