Manager, Computational Biology (Early Oncology)

Manager, Computational Biology (Early Oncology) New York, New York; Salt Lake City, Utah Your work will change lives. Including your own. As a Manager within Recursion's partnership-facing data science team, you will be at the forefront of reimagining drug discovery from first principles. You will lead a team of world‑class computational biologists focused on identifying and advancing the next generation of oncology therapeutics. You will act as a "player‑coach," balancing direct technical contribution with the mentorship and strategic leadership of a high‑performing team. Your mission is to integrate Recursion’s massive datasets—phenomics, transcriptomics, and proteomics—to nominate novel targets, validate disease biology, and define the precision oncology strategies that ensure our medicines reach the right patients. In this role, you will: Lead and Develop: Direct and mentor a team of data scientists and computational biologists, fostering a culture of scientific rigor, bold experimentation, and continuous professional growth. Drive Target Discovery: Lead the design and execution of analyses for target nomination and validation, using Recursion’s platform to identify novel vulnerabilities in cancer biology. Define Early Patient Population Strategy: Develop biomarker strategies and patient‑stratification hypotheses to support programs as they progress from nomination through hit‑to‑lead and lead‑optimization. Bridge the Gap: Act as a key "connector," leading your team to pilot innovative analysis methods and collaborating with platform and engineering teams to productionalize and scale these tools for organization‑wide impact. Execute Hands‑On: Maintain a 50% individual contribution (IC) load, performing complex data integration and analysis to solve "killer questions" within the oncology portfolio. Collaborate Cross‑Functionally: Partner with biologists, medicinal chemists, and clinical leads to build compelling data packages that drive program milestones and investment decisions. Present: data analysis to external decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients. The Team You’ll Join Our group is a bold, agile, diverse collective of computational drug discovery scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. We are a computational group that spans precision oncology, I&I (immunology and inflammation), and neuroscience and focuses on advancing novel, targeted therapies for these disease areas. We partner closely with our biologists and medicinal chemists to design and execute impactful and decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and supported by computational leadership in designing scalable and reproducible experiments that serve to advance multiple programs within the portfolio. Our team collaborates extensively with computational biologists in other therapeutic areas (neurobiology, immunology, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. The Experience You’ll Need PhD in a quantitative field (Computational Biology, Bioinformatics, Statistics, Cancer Biology, etc.) with 5+ years of experience in biotech or pharma industry OR MS in a relevant field and 7+ years of experience in biotech or pharma industry solving fundamental problems in oncology or drug discovery. People Management Experience: Proven track record of managing and developing direct reports within a scientific or technical environment. Oncology Domain Expertise: Deep understanding of cancer biology, including experience with biomarker discovery and patient population stratification. Experience with two or more oncology areas; strong understanding of patient genetics and historical druggability of disease relevant pathways. Deep expertise in the analysis and data integration of two or more ’omics data modalities (phenomics, transcriptomics, proteomics, genomics), including experience working with patient data. Exceptional data visualization skills. Computational Proficiency: Advanced skills in Python or R for the analysis of high‑dimensional biological data (e.g., transcriptomics, proteomics, or high‑content imaging). Excellent Cross‑Functional Communication: Ability to distill complex technical concepts into clear and compelling narrative for internal and external‑cross functional audiences. Nice To Have Public Data Mastery: Familiarity with large‑scale oncology datasets such as TCGA, CCLE, DepMap, and/or Real‑World Data (RWD). Experimental Design: Experience designing high‑throughput screens or CRISPR/small‑molecule perturbations to validate therapeutic hypotheses. Clinical Translation: Exposure to the requirements for IND‑enabling studies or clinical trial biomarker analysis. Working Location This is an office‑based, hybrid role in either our Salt Lake City or New York City offices. Employees are expected to work in the office at least 50% of the time. Compensation Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $151,800 to $230,000 . You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. The Values We Hope You Share We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect—showing up, speaking honestly, and taking action. We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. We move with urgency because patients are waiting. Speed isn’t about rushing but about moving the needle every day. We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy—leaders take accountability for decisive action, and teams own outcomes together. We are One Recursion. True cross‑functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical‑stage TechBio company decoding biology to radically improve lives. Recursion is advancing a portfolio of differentiated investigational medicines across its wholly owned and partnered pipeline in oncology, rare disease, neuroscience, immunology, and other therapeutic areas with significant unmet need. Enabling its mission is the Recursion OS, an AI‑native, end‑to‑end drug discovery and development platform integrating biology, chemistry, and clinical development into a unified intelligence system. Powered by proprietary multimodal data, purpose‑built AI models, and bilingual teams fluent in both science and AI, the Recursion OS is designed to translate complex science into medicines that matter — faster, better, and at scale — for patients who are waiting. Recursion’s platform infrastructure is anchored in Salt Lake City, Utah and Milton Park, Oxfordshire, where its automated biology and chemistry laboratories generate proprietary data at industrial scale. Recursion also maintains offices in New York, Montréal, and London, three global hubs for talent and leadership at the intersection of AI and scientific innovation. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. #J-18808-Ljbffr I did my part and supported the Regular Toilet