Senior Principal Scientist, Neuroscience, Clinical Biomarker, Late Phases, Translational Medicine

Position Summary Translational Development is part of the Global Research organization in BMS and leads late stage clinical, pharmacological and translational research and development activities for the pipeline and supports late stage portfolio for regulatory, translational development and life cycle management. Translational Development drives strategy across core therapeutic areas at BMS including hematology, oncology, immunology, cardiovascular and neuroscience. This group integrates laboratory science, clinical trial/biomarkers and asset development as well as disease research to maximize the potential of BMS current and future therapeutics. Key Responsibilities Designs and implements program‑specific late development biomarker/translational plans, responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement. Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable. Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs. Prepares and delivers internal and external translational/biomarker presentations. Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed. Keeps up‑to‑date on relevant scientific/technical literature in order to apply external knowledge to internal research programs as appropriate and acts as a subject‑matter expert within the team to critically evaluate the literature regarding the asset and disease biology. Works with TM laboratory scientists and academic TLs to address non‑clinical translational questions. Participates in post‑hoc biomarker analysis and publication efforts. Supports regulatory submissions and regulatory interactions as needed. Qualifications & Experience PhD or MD/PhD in neuroscience with 7+ years of translational medicine experience. 5+ years of late‑stage clinical biomarker experience in biotech/pharma. Recognized expertise in translational biomarkers in the neuroscience space. Experience in late‑stage drug development and activities required for and related to clinical trial initiation, maintenance and completion. Strong verbal and written communication skills. Experience in interacting with CROs and TLs to manage projects and timelines. Proven scientific/leadership expertise (working in teams, mentoring people, managing projects). Accountable for timelines and deliverables. Prioritizes risks and implements contingency plans. Communicates regularly; prepares and delivers presentations within the department, to governance and senior leadership bodies, and externally as requested. Recognizes cross‑functional issues and communicates within the larger organization. Provides expert guidance to multi‑disciplinary teams and senior management. Has a track record of delivering results, driving continuous improvements, and building effective cross‑functional networks. Ability to prioritize and manage time efficiently. Accurate and detailed record keeping. Excellent organizational skills. Compensation Overview Brisbane — CA — US $184,060 - $223,036 Cambridge Crossing — $184,060 - $223,036 Princeton — NJ — US $160,060 - $193,949 San Diego — CA — US $176,050 - $213,334 The starting compensation range(s) for this role are listed above for a full‑time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. Benefits Health Coverage: Medical, pharmacy, dental, and vision care. Well‑being Support Programs such as BMS Well‑Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). Financial Well‑being and Protection: 401(k) plan, short‑ and long‑term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support. Paid Time Off: US Exempt Employees flexible time off (unlimited, with manager approval), 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees), etc. Equal Employment Opportunity Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. #J-18808-Ljbffr Bristol Myers Squibb