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Research Associate II - T Cell Therapeutics Research Laboratory

City Of Hope Hospital Duarte - Comprehensive Cancer Center

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. A Research Associate II position is available in the lab of Dr. Christine Brown of the T Cell Therapeutics Research Laboratories (TCTRL). This is a fast-paced lab involved in cutting-edge technology, research and clinical immunotherapeutic programs. You will support the evaluation of CAR T-cell therapies in next-generation cancer models, including patient-derived organoid cultures and organ-on-a-chip platforms, as well as the development and evaluation of novel blood- and iPSC-derived immune effector cell therapies. We will train new personnel in project specific techniques and procedures. Please note, work hours may vary. For an overview of research interests, please visit here As a successful candidate you will: Perform tissue culture using aseptic techniques, including media preparation, passaging, maintenance, and cryopreservation of T cell lines and pluripotent stem cells. Support the development of next-generation solid cancer models, including patient-derived organoids and tumor-on-a-chip platforms. Conduct T cell functional assays, including cytotoxicity and cytokine production assays, as well as ELISAs. Perform cell staining for multicolor flow cytometry and analyze flow cytometry data. Assist with murine surgical procedures, tissue harvesting, and sample preparation. Revise and maintain laboratory protocols and procedures. Provide routine laboratory support and maintenance in accordance with Good Laboratory Practice (GLP) principles. Your qualifications should include: Bachelor’s degree. Masters degree preferred 2+ years of related experience with a Bachelor’s degree or 1+ year related experience with a Master’s degree. Meticulous attention to detail and accuracy in lab work as well as accurate recordkeeping and lab documentation are a must. Hands-on experience with cellular immunology and standard good laboratory practices (GLP) desired City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. #J-18808-Ljbffr City of Hope

Vacancy posted 3 days ago
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