Staff Software Engineer, Scientific System of Record
$144k - $288kLila Sciences
Staff Software Engineer, Scientific System of Record Cambridge, MA USA; San Francisco, CA USA Your Impact at LILA We are seeking a Staff Software Engineer to join our Scientific System of Record Team and help build the next-generation AI-driven scientific platform. You will focus on developing user interfaces, services, high-performance APIs, databases, and reliable systems that integrate advanced AI frameworks with complex scientific analytics and laboratory workflows. You'll work closely with ML researchers, platform engineers, and scientists to develop systems that can handle diverse workloads and scale seamlessly, including structured SQL databases, data lakehouses, workflow engines, and lab execution environments. This is an opportunity to apply your deep front-end and backend expertise to a cutting-edge AI platform with real scientific impact. If you are passionate about building performant, elegant systems, we would love to hear from you. About The Team The Scientific System of Record Team (SSR) builds the memory layer for Lila's operations. It answers two questions: what did we plan to build? and what actually happened? These systems connect scientific intent to physical reality. Together with the data and automation teams, their systems ensure reproducibility and close the Design-Build-Test-Learn (DBTL) loop. What You'll Be Building User Interfaces and APIs: Design and build high-performance, secure, and well-documented UIs and APIs that integrate with AI-driven applications. Database Architecture and Scaling: Develop schemas and manage diverse data systems, including SQL, NoSQL, vector databases, and other emerging technologies, for performance and scalability. Application Development: Drive implementation of front-end and backend services with a focus on performance, maintainability, and reliability. Performance and Reliability: Diagnose and resolve system bottlenecks while ensuring high availability and low-latency performance across large-scale workloads. Cloud and Infrastructure: Leverage AWS services, Kubernetes, and modern DevOps practices to build and deploy production-grade systems at scale. Cross-Functional Collaboration: Work with ML researchers, engineers, and scientists to integrate data pipelines, APIs, and cloud infrastructure into scientific workflows. What You'll Need to Succeed Bachelor's or Master's degree in Computer Science, Engineering, or related field. 6–8+ years of engineering experience building and deploying large-scale systems in production. Strong expertise in at least one of the following areas, with the ability to work across the stack: front-end engineering, backend engineering, or data modeling and system design. TypeScript, React, and Python: Strong experience with React and TypeScript is required; Python experience is strongly preferred. Databases: Strong experience with SQL, NoSQL, and emerging database technologies such as vector databases; proven track record in schema design, indexing, and query optimization. API Development: Proven ability to design and scale RESTful or GraphQL APIs with a focus on reliability and performance. Hands-on experience using AI coding assistants to improve engineering productivity. Scientific or Data-Intensive Domains: Experience working in life sciences, materials science, or other research-heavy or data-intensive fields. Communication and Collaboration: Strong listening skills and a proven track record of working cross-functionally with scientists, data engineers, and product teams; able to explain complex ideas to diverse audiences. Problem Solving: Proven ability to take ownership of complex technical challenges while balancing trade-offs between scalability, performance, and maintainability. Bonus Points For Cloud and DevOps: Hands-on experience with AWS, GCP, or Azure; strong understanding of Kubernetes, containerization, infrastructure as code such as Terraform or CloudFormation, and CI/CD pipelines such as GitHub Actions. Orchestration Systems: Experience with orchestration tools such as Flyte, Temporal, Airflow, Prefect, or similar systems. Experience building laboratory, scientific workflow, LIMS, ELN, data platform, or ML platform products. Experience designing systems that support auditability, traceability, reproducibility, data provenance, or regulated workflows. Compensation We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact. U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market. Expected Base Salary Range
$144,000 - $288,000 USD
About LILA Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves. LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply. We're All In Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy. A Note to Agencies Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto. Lila Sciences- Member Of The Technical Staff - Software Engineer (UI/UX) About Transfyr Transfyr is building... ...happen. A publication is a lossy record of what might have worked. But... ...that. Transfyr builds physical AI systems that capture real scientific work and turn it into a high-fidelity...ScientificApprenticeship
- ...monitor, explain, and improve AI systems in production, particularly... ...AI with confidence. As a Staff Engineer, you’ll lead the development... ...of both AI systems and software engineering to solve open-ended... ..., Engineering or related scientific field or equivalent experience...ScientificFull timeWork at office
$220k - $292k
...diverse team of experts in software, robotics, artificial intelligence... ...generation of autonomous systems to tackle the extremely... .... About the Job Staff Software Engineers lead the delivery of a variety... ..., adverse media, public-record information, and other lawful...SuggestedFull timeWork experience placementImmediate startRemote workFlexible hours$146.6k - $215.1k
...exceptionally talented and hands-on Staff Backend Software Engineer to drive the technical direction and architecture of our core backend systems. This role is key to accelerating technical... ...skills, with a proven track record of influencing technical decisions across...SuggestedFull timeWork at office$234k - $300k
...monitor, explain, and improve AI systems in production, particularly... ...AI with confidence.As a Staff Engineer, you’ll lead the development... ...understanding of both AI systems and software engineering to solve open-... ..., Engineering or related scientific field or equivalent...ScientificWork at office- ...is building a new class of AI systems designed to reason with the rigor of the scientific method. By combining deep learning... ...in high-stakes scientific and engineering workflows. Our mission, 30×... ...Position Overview As Staff Software Engineer (Backend) , you will...ScientificFull timeWork at officeRemote work
$130.8k - $209.4k
...operations, lifecycle management, system architecture, performance... ...to ensure documentation, records, and system evidence are accurate... ..., Information Technology, Engineering, or related field.10-12 years... ...the driving force behind our scientific progress and our culture. Together...ScientificPermanent employmentFull timeWork at officeWork from home- ...Title: System Engineer Location: Onsite, Boston, MA Type: Contract to Hire Hours:... ...assigned portion of the integration readiness record and execute verification activities for... ...processes. #M3 #LI-DS2 Ref: #558-Scientific PDN-a2d1ca59-bcf4-4820-8c15-4fa86a...ScientificContract work
$92k - $148.35k
...DevelopmentJob Sub Function: R&D Software/Systems EngineeringJob Category:Scientific/TechnologyAll Job Posting Locations... ...are searching for Senior System Engineer to be based out of Boston,... ...characterization tests) and accurately recording results under the guidance of test...ScientificFull timeWork at officeLocal areaImmediate start3 days per week$172.2k - $266.51k
...validates, and commercializes software as prescription... ...technical and scientific rigor and patient-centric... ...designers, technologists, engineers and more, united in a... ...Native and Node.js-based systems, from initial planning... ..., with a track record of shipping production...ScientificPermanent employmentTemporary workWork at officeLocal areaVisa sponsorshipFlexible hours$128k - $208k
SummaryLaser Systems is QuEra’s laser infrastructure... ...seeking a Laser Systems Engineer to join this team in... ...documentation, and integration records; coordinate vendor... ...with Hardware, Software, Systems Engineering,... ...integration in a precision or scientific instrumentation...Scientific$230k - $295k
...Zoox is looking for an experienced Staff Software Engineer to build, scale, and operate our custom... ...and performance Identify and resolve systemic reliability and performance issues through... ...on AWS or similar providers Track record of shipping and operating reliable,...Full timeTemporary workRelocation package$220k - $292k
...environment includes not just the software used to design, plan, and... ...operators, machines, test systems, and OT networks into the... ...We are looking for a Staff Software Engineer to join ArsenalOS, the digital... ...watchlists, adverse media, public-record information, and other...Full timeTemporary workWork experience placementImmediate start$174k - $205k
...more. Perk is growing its engineering footprint in North America, and we're looking for a Staff Software Engineer to help us do it right... ...design scalable, evolvable systems and articulate a clear technical... ...and influence: a track record of levelling up engineers around...Full timeWork at officeImmediate startWorldwideRelocation package3 days per week$146.6k - $195.5k
...SimpliSafe's Enterprise Information Systems team is on a mission to improve how our... ...performance, and reliability. As a Staff Software Engineer, you'll help shape the future of our e... ...js and TypeScript, with a strong track record of building and scaling production applications...Full timeWork at office- ...members of our Android team at the Senior and Staff levels. These aren’t maintenance roles —... ...ll own major features end-to-end, drive engineering quality, and contribute to architectural... ...with backend engineers Track record building 0→1 consumer products at a fast...Full timeWork at officeLocal areaWorldwide
$144k - $210k
...science! We are seeking a Senior Software Engineer with full stack experience... ...-edge tools for automated scientific analysis and more. This role... ...: Diagnose and optimize system bottlenecks, ensuring high availability... ...skills, and a proven track record of working cross-...ScientificFull timeWork at officeLocal areaFlexible hours$120k - $150k
...Software Engineer in Test US REMOTE (AZ, CA, CO, FL, GA, MA, MD, NC, NJ... ...measures backed by rigorous scientific and analytic expertise.... ...automated unit, integration, API, system, and regression tests.... ..., test evidence, or release records. Experience with system...ScientificRemote workFlexible hours$195.5k - $352.1k
...throughput and low latency systems responsible for serving relevant... ...operates with the high engineering rigor that this demands.... ...RoleWe're hiring a Senior Software Engineer (Staff scope) to help scale and evolve... ...upA demonstrated track record of owning complex systems end...Work at officeLocal areaImmediate startRemote workMonday to ThursdayFlexible hours$220k - $292k
...changing how military systems are designed, built and... ....ABOUT THE TEAMThe Software Platform Foundations team... ...that empower our engineering teams to develop, test... ...products fast. As the Staff Software Engineer, Quality... ...adverse media, public-record information, and other...Full timeContract workWork experience placementLocal areaImmediate start$134.64k - $201.97k
...analog, digital, AI, and software technologies into... ...and on LinkedIn and X.Staff Software EngineerJoin our... ...dynamic group of software engineers, hardware engineers, scientists... ...of our Platforms and Systems team, you'll tackle... ...with the otherTrack record of architecting, building...Permanent employmentFull timeWork at officeDay shift$228k - $240k
...service to seller and buyer clients.As a Staff Software Engineer in the Transaction Journey (TJ)... ...making yourself understood.You design systems that are fault tolerant, scalable, highly... ...using AWS / cloud technologiesA track record as a technical leader with cross-team...Minimum wageFlexible hours- ...industry, Anduril is changing how military systems are designed, built and sold. Anduril’s... ..., not years.This role is a shared software engineering pipeline for the teams building the systems... ...and watchlists, adverse media, public-record information, and other lawful open-...Full timeTemporary workWork experience placementLocal areaImmediate start
$170k - $188k
...a secure web browser interface. As a Staff Software Engineer on the platform services team, you will... ..., security vulnerabilities, and other system limitations. Keep up to date with industry... ...(Docker, Kubernetes) Proven track record of designing and building highly available...Ongoing contractFull timeCasual workWork at officeWorldwideFlexible hours$163.4k - $217.87k
...Lila Sciences is seeking a Staff Senior Systems Engineer, OT to design, build,... ...services without exposing scientific IP. Own commissioning and... ...documented exceptions where vendor software constrains standard... ...hosted Git forge as source of record, and tiered storage from...ScientificFull timeWork at officeLocal areaRemote workFlexible hours$73.08 per hour
...Title: System Engineer Location: Onsite, Boston, MA Type: Contract to Hire Hourly... ...assigned portion of the integration readiness record and execute verification activities for... ...processes. #M3 #LI-DS2 Ref: #558-Scientific PDN-a2d1ca59-bcf4-4820-8c15-4fa86a...ScientificHourly payFull timeContract work$228k - $363k
...pipelines, and the notification systems that power it. You'll report to the Songkick Engineering Manager and work closely with... ...sources into a single canonical record Assess a large, established... ...Must-Haves ~5–10 years of software engineering experience, with a...Work at officeLocal areaFlexible hours- ...a higher level through a deeper understanding of their bodies and daily lives. WHOOP is hiring a Software Engineer II (Backend, Health Records) to help build the systems that enable secure, scalable ingestion and utilization of health data. In this role, you will contribute...Full time
- ...drug discovery to machine learning. QuEra is seeking a Scientific Software Engineer to develop and maintain our in-house quantum hardware emulator... ..., NVIDIA Nsight, VTune, or equivalent). Strong track record of contributions to open-source scientific or quantum...ScientificFull time
$254k - $350k
.../ Boston, MA / Seattle, WASoftware - Autonomy Software /Full-time /HybridThe Perception team is pioneering... ...to drive the next generation of autonomous system intelligence.As a Machine Learning and System Optimization Engineer, you will orchestrate and allocate overall...Full timeTemporary workRelocation package
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