Senior Director, AIRx Discovery Biology Lead
Scorpion Therapeutics
Senior Director, AIRx Discovery Biology Lead Responsibilities / Accountabilities Own disease biology and target validation strategy across the AIRx portfolio; ensure mechanistic rationale, differentiation, and clinical line of sight. Define translational biomarker strategies for go/no-go decisions and future clinical development. Design and provide strategic oversight of CRO-executed in vitro and in vivo biology studies; critically evaluate data packages for quality and decision-readiness. Integrate biology data into AI-enabled DMTA cycles with medicinal/computational chemists, DMPK, safety, and structural biology. Challenge scientific assumptions to ensure biological integrity and mechanistic depth in program decisions. Represent biology at governance forums; contribute to IND-enabling biology packages. Stay current with disease biology and the competitive landscape; proactively inform the team. Shape and role‑model how biology is practiced in the AIRx operating model. Qualifications / Competencies PhD in cell biology, molecular biology, pharmacology, or related field. 12–15+ years drug discovery experience with strong target validation and disease biology track record. Proven IND contributions; experience supporting IND-enabling biology packages. Experience designing/managing externalized CRO biology programs; ability to scope, oversee, and interpret study data. Ability to connect target biology to clinical hypothesis and translational strategy. AI/ML data integration experience; comfortable with large multi-source datasets. Experience in at least one therapeutic area in the Takeda Research portfolio. Excellent cross‑functional collaboration; effective in lean, fast‑paced teams. #J-18808-Ljbffr Scorpion Therapeutics
Vacancy posted 2 days ago
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