Senior Neuro iPSC Disease Modeling Scientist (CRISPR)
Genentech
Genentech is seeking a highly motivated Scientist to advance research and drug discovery in Neuroscience by leading iPSC‑derived CNS models, CRISPR engineering, and functional assays in a collaborative, fast‑paced team. You will design and optimize differentiation protocols, run CRISPR screens, develop 3D co‑culture systems, perform qPCR/RNA‑seq/proteomics, analyze data, and present findings to project teams and leadership. #J-18808-Ljbffr Genentech
$103.4k - $192k
...motivated, hands‑on, and creative Scientist to advance research and... ...application of complex iPSC‑derived in vitro models and functional assays to... ...mechanisms of neurodegenerative diseases, directly informing... ...in stem cell biology and CRISPR engineering together with...SuggestedLocal areaRelocation package$156k - $166k
insitro is seeking a Senior Scientist for its cardiac disease biology team in South San Francisco. This pivotal role involves working on iPSC-derived cardiomyocyte models to advance our ML-driven drug discovery efforts. You will design experiments, optimize workflows, and...SeniorFlexible hours$156k - $166k
...multiple programs in metabolic disease and neuroscience... ...point.We are seeking a Senior Scientist to join our cardiac disease... ...and application of iPSC-derived cardiomyocyte (iPSC-CM) models to study the genetic and... ...disease models — including CRISPR-edited lines carrying disease...SeniorWork at officeHome officeFlexible hours$113.3k - $169.9k
...and diagnosis of diseases and new treatment... ...talented experimental scientist to lead a multi-... ...genetics, using human IPSC systems. Illumina’... ...requirements(Senior Scientist) Ph.D in... ...development of iPSC models, primary cell... ...sequencing assays, CRISPR, single cell sequencing...SeniorFull timeLocal areaWorldwide- ...South San Francisco, CA is seeking a Scientist 2 in Neuroscience Discovery & iPSC Assay Development to advance discovery research. You will generate CNS cell models from human iPSCs, execute functional assays, and support disease-relevant phenotyping in a fast-paced team...Suggested
- Xaira Therapeutics in the San Francisco Bay Area is seeking a Senior Scientist to architect and lead in vivo CRISPR screening. You will push high-throughput functional genomics at the intersection of mouse models, AI/ML, and translational biology to accelerate therapeutic...Senior
- Xaira Therapeutics is seeking a Senior Scientist to architect and lead in vivo CRISPR screening efforts, spanning mouse models, data science, AI/ML, and translational biology. You will translate genetic screening insights into therapeutic discovery while balancing strategic...Senior
$85.5k - $158.7k
...motivated and collaborative Scientist 2, Neuroscience Discovery & iPSC Assay Development to... ...nervous system (CNS) cell models, execute functional assays, and support disease-relevant phenotyping. You will... ...or hands-on experience with CRISPR/Cas9 gene editing, arrayed/...Full timeLocal areaRelocation package- ...San Francisco, CA, is seeking a PhD‑level scientist to execute the experimental plan across iPSC‑based astrocyte and microglia models. You will own specific arms, optimize protocols... ...along with a path to Scientist II / Senior Scientist as the program grows. #J-18808-...SeniorShift workWeekend workAfternoon shift
- ...platform. We pair human iPSC-derived 3D neural models with custom automation, imaging... ...of neurological disease biology and enable therapeutic... ...the VP of Biology, the Scientist | Senior Scientist will drive the... ...engineering strategies using CRISPR | Cas systems, including...Senior
$131.4k - $206.8k
...motivated, energetic, and skilled Senior Scientist (R3) with a strong in-vitro... ...to join the Cardio-Metabolic Disease (CMD) department. This is a... ...validate complex in-vitro models and establish sets of in-vitro... ...development, metabolic diseases, neuro-endocrine diseases....SeniorFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$130.8k - $242.8k
...and novel computational models to drive impact.... ...Intelligence (AI) to assist our scientists in delivering more... ...and neuroinflammatory diseases such as Alzheimer’s,... ...study these pathways (Senior Scientist). Additionally... ...-seq and related CRISPR screeningPatient tissue...SeniorFull timeLocal areaWorldwideRelocation package3 days per week$167.4k - $310.8k
...leveraging data and novel computational models to drive impact. Seamless data sharing and... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative... ...(ML) techniques. We are seeking a Senior or Principal Machine Learning Scientist...SeniorFull timeLocal areaWorldwideRelocation package$160k - $197k
...harness advanced technologies and model systems to increase our... ...innovative, technology-driven Scientist to join our teams. This role offers... ...age and age-related disease. A primary area of focus will... ...models (e.g. primary culture, iPSC-derived neurons, microglia)Experience...Senior- A leading biotechnology company in South San Francisco is seeking a Senior or Principal Machine Learning Scientist. In this role, you will lead the development of large language models for drug discovery tasks. You will work on designing scalable systems and translating...Senior
$124.3k - $230.9k
...department at Genentech is seeking a Ph.D. level Senior Scientist who is highly motivated to apply cutting edge translational modeling approaches to support the advancement of... ...the aspiration to prevent, stop and cure diseases.This position does offer domestic...SeniorFull timeLocal areaRelocation- Genentech, a member of the Roche group, seeks a PhD-level Senior Scientist to advance translational PBPK modeling for small molecule drug discovery and development. The role focuses on physiologically-based pharmacokinetic analyses and cross-functional collaboration in...SeniorRelocation
- F. Hoffmann-La Roche AG is looking for a highly motivated Senior ML Scientist to join the Foundation Models team in South San Francisco. This position focuses on pioneering AI research that impacts drug and target discovery. The ideal candidate will have a Ph.D. and a strong...Senior
$113k - $171k
...medicines to treat age-related diseases by reprogramming the... ...screening, and machine learning models to unravel the biology of epigenetic... ...NewLimit is seeking a scientist with experience in discovery... ...single cell read-outs (e.g. CRISPR fitness screens, Perturb/CROP...Senior$130k - $180k
...medicines to treat age-related diseases by reprogramming the... ...screening, and machine learning models to unravel the biology of epigenetic... ...seeking a highly motivated Scientist/Senior Scientist in Immunology to... ...single-cell readouts (e.g., CRISPR fitness screens, Perturb-seq...Senior$104.7k - $194.4k
...seeking a highly motivated and innovative Senior Scientist to join our team. This unique role... ...cell pluripotency, differentiation, and disease modeling. The ideal candidate possesses deep... ...culture including differentiation of human iPSCs/ESCs into specific lineages to study...SeniorLocal areaRelocation packageShift work- ...team in identifying cancer molecular signatures and advancing models for clinical products. The role combines genome-scale analyses... ...applications. You will guide model development, collaborate with ML scientists, and drive projects from hypothesis to implementation while...Senior
- ...against the world's toughest diseases. With our focus on four... ...while transforming your career. Senior Scientist, Target Discovery & Biology... ...including complex biological models from in vitro to in vivo, to... ...genetic screens (particularly CRISPR-based) and follow up...SeniorFlexible hours
$202.8k - $376.6k
...data and novel computational models to drive impact. Seamless data... ...(AI) to assist our scientists in both pRED and gRED to deliver... ...generating new insights into disease mechanisms, therapeutic opportunities... ...of AI for biology.As a Senior Principal Scientist, you will...SeniorFull timeLocal areaWorldwideRelocation package$147.8k - $274.4k
...data and novel computational models to drive impact. Seamless data... ...(AI) to assist our scientists in both pRED and gRED to deliver... ...motivated and collaborative Senior/Principal Machine Learning Scientist... ...development of treatments for disease.Technical Skills:Proficiency...SeniorFull timeLocal areaWorldwide$90k - $128k
...development for autoimmune disease. Based in South San... ...Francisco, California, our scientists are pioneering... ...motivated and skilled Senior Research Associate / Associate... ...., viral transduction, CRISPR, reporter line... ...in autoimmune disease models is highly desirable...Senior- Genentech is seeking a Scientist 2 in Neuroscience Discovery & iPSC Assay Development to advance discovery research and drug development... ...leverage human iPSCs to generate CNS cell models, run functional assays, and support disease-relevant phenotyping with rigorous data...
- ...approaches to Alzheimer's disease and other... ...Neurodegeneration world model, reconciling over 1,800... ...platform enables Fulcrum scientists to explore target and therapeutic... ...s experimental plan in iPSC-based and primary... ...translates into Scientist II / Senior Scientist roles as the...SeniorFull timeContract workTemporary workPart timeRelocationAfternoon shift
$124.3k - $230.9k
...clearly to multidisciplinary teams and senior stakeholders.Preferred Experience as a member... ....Hands-on experience with PK/PD modeling and/or PBPK modeling using relevant modeling... ...the aspiration to prevent, stop and cure diseases.This position does offer domestic...SeniorFull timeLocal areaRelocation$183k - $238k
...relationship between these phenotypes and human disease and translating them into actionable... ...analysis, systems biology, graph-based modeling, causal structure learning, single cell... ...biologists, and other machine learning scientists, support the identification of novel...SeniorHome officeFlexible hours
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