Postdoctoral Associate

Job Description The Sahoo Lab is seeking a motivated Postdoctoral Associate to study the genetic and functional mechanisms driving inherited bone marrow failure and predisposition to MDS/AML. This NIH-funded position focuses on defining how germline gain-of-function mutations activate chronic inflammatory signaling, impair hematopoietic stem cell function, and drive progression to myeloid malignancy. The project integrates mouse and iPSC models, CRISPR genome editing, molecular biology, flow cytometry, and single-cell multi-omics to dissect disease mechanisms. We are committed to mentoring the whole scientist. The successful candidate will lead this project while growing toward research independence, supported by an individualized development plan, structured mentorship, and clear milestones tailored to their career goals. Postdocs are actively mentored to publish, present, build collaborations, and compete for fellowships and career-development awards (e.g., NIH F32, K99/R00). The position is funded for up to three years, with full access to Virginia Tech and Children's National Hospital core facilities and seminars. The candidate will also have the opportunity to mentor and train junior scientists, developing the leadership and mentoring skills essential to an independent career. This is an exciting opportunity to play a foundational role in a growing lab at the Research and Innovation Campus in Washington, DC. We are building an inclusive, collaborative lab culture and welcome applicants of all backgrounds, identities, and career paths. We are especially eager to hear from individuals historically underrepresented in biomedical research. Required Qualifications Ph.D. in hematology, genetics, molecular biology, cancer biology, or a related biological science. The Ph.D. must have been awarded no more than four years prior to the effective date of the appointment, with at least one year of eligibility remaining. Hands‑on experience with mouse models of hematopoiesis and/or cancer, including in vivo techniques such as blood collection and tail‑vein injection. Experience with primary hematopoietic stem and progenitor cells and/or iPSC models. Proficiency in wet‑lab techniques, including molecular biology, mammalian cell culture, and flow cytometry. Experience with CRISPR‑based genome editing. Self‑motivated, creative, and detail‑oriented. Excellent organizational and time‑management skills. Excellent communication skills. Ability to work both independently and as part of a collaborative team. Experience mentoring or training students and/or research staff. Preferred Qualifications Familiarity with single‑cell multi‑omics approaches. Analysis of large‑scale genomic and/or transcriptomic datasets. Experience with mitochondrial or innate immune/inflammation assays. Additional Information The successful candidate will be required to have a criminal conviction check. Overtime Status Exempt: Not eligible for overtime. Appointment Type Restricted. Salary Information $65,000-$71,000, commensurate with experience. Hours per week 40+ Review Date 7/24/26 Equal Employment Opportunity Statement Virginia Tech does not discriminate against employees, students, or applicants on the basis of age, color, disability, sex (including pregnancy), gender, gender identity, gender expression, genetic information, ethnicity or national origin, political affiliation, race, religion, sexual orientation, or military status, or otherwise discriminate against employees or applicants who inquire about, discuss, or disclose their compensation or the compensation of other employees or applicants, or on any other basis protected by law. Accommodation If you are an individual with a disability and desire an accommodation, please contact Brittany Shelton at View email address on click.appcast.io during regular business hours at least 10 business days prior to the event. #J-18808-Ljbffr Virginia Polytechnic Institute and State University (VT)