Principal ScientistSenior Principal Scientist, Material Science & Engineering at Bristol Myers [...]

Working with Us Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high‑achieving teams. Take your career farther than you thought possible. Job Description As a Principal or Senior Principal Scientist in the Drug Product Development – Materials Science and Engineering Group the main responsibilities will be developing understanding of the material options for novel drug candidates and driving the selection of commercial materials. The candidate is expected to apply biopharmaceutics, physical chemistry and engineering principles to achieve these goals. Primary activities and responsibilities will include: Screening for polymorphs of neutral molecules, salts and cocrystals to support material selection Perform solid state material characterization of novel materials Perform solid state physical and chemical stability assessments on selected lead materials Develop understanding of the polymorph landscape and thermodynamic relationships between polymorphic forms leveraging automated and manual experimentation as well as connecting with predictive modeling Connect selection of materials into the manufacturing stability and performance of drug products Provide leadership and supervision to scientific staff. Develop coach and mentor others. Participate in and lead cross‑functional materials teams for novel drug candidates to drive materials strategy at the interface of drug substance and drug product. It is expected that the candidate will work with a broad range of materials such as crystalline and non‑crystalline APIs including small molecules, peptides, oligonucleotides as well as drug product intermediates that will be used in the design of robust oral and injectable drug product formulations. This role may be appointed at the Principal Scientist or Senior Principal Scientist level. Candidates with demonstrated experience and expertise will be considered for the appropriate level. Requirements Principal Scientist: Pharmaceutics, Pharmaceutical Science, Pharmaceutical Chemistry, Organic Chemistry, Chemical Engineering or related field with 46 years of industry experience or MS with 69 years or BS with 912 years Senior Principal Scientist: Ph.D. in a relevant field (e.g. physical chemistry, materials/pharmaceutical science, chemical engineering) with 68 years of industry experience or MS with 912 years or BS with 1215 years Excellent problem‑solving skills with a strong background in biopharmaceutics and pre‑formulation are required. Hands‑on experience in laboratory experimentation and expertise in solid state characterization techniques such as XRD, BET, moisture sorption, thermal techniques such as TGA, DSC and hot stage microscopy, optical and electron microscopy, vibrational spectroscopy and chromatography techniques is preferred. Experience with polymorph screening and salt/form selection is required. Familiarity with high‑throughput experimentation and data analysis is desired. Experience with complex molecules such as millamolecules, oligonucleotide peptides and proteins is desired. Experience with direct management and with cross‑functional team leadership is also desired. A demonstrated record of scientific accomplishment, laboratory experimentation, publication and presentation is required. The individual will effectively interface and collaborate across drug substance, drug product and analytical development teams. The individual must have demonstrated ability to identify and solve problems. Outstanding oral and written communication skills with the ability to provide technical input and scientific leadership are required. This position requires employees to work safely at laboratory scale with chemical agents which may pose health or safety hazards if improperly handled. Compensation Overview New Brunswick – NJ – US: $138,190 – $167,457 The starting compensation range(s) for this role are listed above for a full‑time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job such as required skills where the job is performed, the employees work schedule, job‑related knowledge and experience. Final individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary by job and location. For more on benefits please visit: our offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well‑being resources and a 401(K). Financial protection benefits such as short‑ and long‑term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work‑life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Years, holiday up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off and summer hours flexibility. Parental caregiver bereavement and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program. Equal Employment Opportunity BMS is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations and ongoing support in their roles. BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area. #J-18808-Ljbffr