Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Software Engineer - AI Systems

$150k - $250k

NxT Level

Senior Software Engineer (Agentic AI / Healthcare)Location: New York, NY (Manhattan), Hybrid (3 days onsite) Compensation: $150,000–$250,000 base + equity Contact / Apply: Ryan Johnston - View email address on click.appcast.io Our ClientOur client is a venture-backed healthcare technology company based in New York and Toronto, building agentic AI solutions that reimagine how medications are prescribed, verified, and supported across the pharmacy ecosystem. Backed by $4M in funding and trusted by multiple Fortune 50 healthcare organizations, they're scaling quickly and expanding their AI product line.As an early engineering hire, you'll play a meaningful role in shaping architecture, shipping production systems, and balancing speed with quality. The work directly impacts pharmacy workflows and, most importantly, patient outcomes.MissionOur client is building a world where medication delays are impossible. From the moment a prescription is written, the path to therapy start should be clear, fast, and predictable. Their platform connects the fragmented steps that slow medication access, intake, coordination, utilization management, and clinical services, so patients start therapy sooner.The RoleOur client is hiring a Senior Software Engineer to design and build autonomous, agentic systems that run complex, multi-step pharmaceutical workflows end-to-end. This is a backend-leaning role with broad scope: you'll work across orchestration, integrations, reliability/observability, and the practical realities of healthcare systems.This role is ideal for someone who enjoys ambiguous problems, can ship end-to-end, and wants to build real product in a regulated, high-stakes domain.What You'll DoDesign and build autonomous agents that handle multi-step pharmacy workflows end-to-endArchitect communication systems that coordinate across organizational boundaries (providers, payers, pharmacies, vendors)Build orchestration layers for long-running tasks, including graceful failure handling and human-in-the-loop escalationDevelop frameworks enabling agents to interact with external pharmacy systems, databases, and APIsImplement evaluation + observability infrastructure to monitor agent behavior in production (quality, drift, failure modes)Integrate with healthcare data standards and legacy pharmacy systemsScale systems for real-time processing across multiple pharmacy networksWhat Our Client Is Looking For5+ years of software engineering experience with a strong backend focusProficiency in Python or TypeScript and deep backend fundamentals (APIs, data stores, concurrency, distributed systems)Experience with service-oriented architectures and web frameworks (FastAPI, Flask, or equivalent)Strong API design skills (clean, versioned APIs)Familiarity with caching, messaging, and databases (e.g., Redis, Kafka, SQL/NoSQL, vector databases) and how to apply them for performance and reliabilityCloud experience (Azure, AWS, or GCP)Experience building and deploying agentic AI systems, including tool use, planning, memory, and orchestration patternsProven ability to ship ambiguous projects end-to-end with minimal guidance and own outcomesBased in NYC and able to commute to Manhattan 3 days/weekNice-to-HavesExperience integrating with healthcare/pharmacy systems or healthcare data standardsExperience building evaluation harnesses for agent reliability and hallucination mitigationPrior work in regulated environments where correctness and auditability matterCompensation & PerksCompetitive compensation: $150k–$250k base + stock optionsFull medical, dental, vision coverageUnlimited PTO + 2 weeks company-wide holiday closureComplimentary breakfast daily and weekly team lunches (in-office)Professional development stipendWhy This RoleThis is a rare opportunity to be early, own architecture, and build agentic systems that directly improve medication access—where execution quality matters and the impact is tangible.

Vacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Senior Software Engineer - AI Systems in New York, NY vacancy
  • $244k - $305k

     ...customer applications perform under real workloads at scale. As AI reshapes software development and teams lose touch with how their code works...  ...tuning to root cause analysis. As a distributed systems engineer on the profiling team, you will be contributing to the systems... 
    Senior
    Work at office

    Datadog

    New York, NY
    5 days ago
  • $192k - $240k

    Distributed Systems engineers at Datadog design, implement and run in production the foundational...  ...customersYou have demonstrated ability to use AI coding tools in day-to-day workflows and...  ...the boundaries of how AI can improve software engineering best practices and... 
    Senior
    Work at office

    Datadog

    New York, NY
    7 days ago
  • $159.8k - $235k

     ...Scalability team owns build systems and continuous integration across...  ..., the cost of building software can grow for everyone. We tackle...  ....About the RoleAs a Senior Software Engineer on Code Scalability, you will...  ...and CI platform can do with AI: move beyond reporting failures... 
    Senior
    Hourly pay
    Work at office
    Local area
    Remote work
    Flexible hours

    Doordash

    New York, NY
    4 days ago
  • $220k - $300k

     ...client is a Series A point-of-sale software company in NYC, building the #1 operating system for local retailers. Our...  ...integrations, marketing, bookkeeping, and AI agents. It lets the owners of...  ...call us by name. AI-assisted engineering isn't a talking point here. Agents... 
    Senior
    Local area
    Afternoon shift

    Simplex

    New York, NY
    4 days ago
  • $202k - $230k

     ...Company StackAI (by Asana) is a no-code AI workflow platform that empowers...  ...that work runs on a single engine. Some agents finish in a second. Others...  ...losing a step. We're hiring a Senior Software Engineer, Engine & Distributed Systems to own that engine: the durable runtime... 
    Senior

    StackAI

    New York, NY
    3 days ago
  • $150k - $300k

     ...Senior Software Engineer, Agentic Systems Manhattan, NY Engineering Hybrid Full-time Asepha is based in New York and Toronto, building agentic solutions...  ...architectural decisions and writing code to expand our AI product line. You will play a pivotal role in balancing... 
    Senior
    Full time
    Work at office
    Local area
    3 days per week

    Asepha

    New York, NY
    3 days ago
  • $145k - $200k

     ...Senior Software EngineerPalantir builds the world's leading software for...  ...are seeking a Senior Software Engineer to join a customer-facing product...  ...Software for Autonomous Systems for use in operational and tactical...  ...detectionBuild LLM and AI-driven systems capable of assessing... 
    Senior
    Work experience placement
    Work at office
    Remote work
    Work from home
    Relocation package

    Palantir Technologies

    New York, NY
    4 days ago
  • $186.07k - $218.9k

     ...called “surges.”learn more about working at Coinbase. As a Senior Software Engineer on the Core Infra Systems team within the Platform group, you'll work across the...  ..., production-ready outcomes. Utilizes generative AI responsibly, maintaining human oversight to deliver business... 
    Senior
    Local area

    Coinbase

    New York, NY
    4 days ago
  • $161k - $239k

    Google is seeking a Software Engineer in New York, NY to develop next-generation technologies for millions of users. The role encompasses working...  ...Learning, Natural Language Processing, and large-scale systems. Applicants should possess a Bachelor’s degree with 6 years of... 
    Senior

    Google

    New York, NY
    4 days ago
  •  ...per week in-office Level: Senior Experience: 8+ years of professional software engineering experience About the Role...  ...under load, and taken ownership of systems throughout their lifecycle....  ...data scientists, research-focused AI practitioners, or engineers whose... 
    Senior
    Work at office
    Remote work
    2 days per week

    InnoveIQ

    New York, NY
    15 hours ago
  •  ...WRITER is seeking an AI engineer to shape how enterprises harness superintelligence. You will build and deploy AI solutions powering the future of work across major clients, ensuring performance, scalability, and ethical alignment of LLMs and AI agents grounded in company... 
    Senior

    Writer Corporation

    New York, NY
    3 days ago
  •  ...Launchpoint is seeking a backend engineer to own core systems end to end, from design through production. You will work with a very small team, handle...  ...reliability in a fast-moving environment. You will apply AI where it matters, set architectural standards, and... 
    Senior

    LaunchPoint

    New York, NY
    17 hours ago
  •  ...Ripple is seeking a Senior Staff Security Engineer focused on AI Security in New York, NY. You will be the deepest technical expert at the intersection of AI and security, guiding security controls across the AI development lifecycle and shaping Ripple's external posture... 
    Senior

    Ripple

    New York, NY
    4 days ago
  •  ...Scale AI is shaping the future of enterprise AI with frontier agents deployed across diverse workflows. You will design, evaluate, and deploy intelligent systems that combine frontier models with structured knowledge, retrieval, and traditional ML, working directly with... 
    Senior

    Frontdoor Defense

    New York, NY
    2 days ago
  •  ...Jobot in SoHo, New York City, seeks a Staff/Senior Software Engineer specializing in Agent Engineering to advance the agent runtime powering the...  ..., and action capabilities. You will own and improve the systems that make agent behavior reliable in production, including... 
    Senior

    Jobot

    New York, NY
    3 days ago
  • $170k - $250k

     ...A tech-focused staffing firm is looking for a mid-senior level Senior AI Engineer to join a dynamic team in New York City. This role involves building advanced agent systems powered by AI and LLMs, focusing on shaping core architecture and delivering exceptional user experiences... 
    Senior
    Work at office

    Oakwell Hampton Group

    New York, NY
    3 days ago
  •  ...Take2 AI in New York City is hiring a Senior Software Engineer, Applied AI to design, build, and scale the AI systems powering Take2's autonomous healthcare recruiting platform. You’ll own applied-AI work end-to-end—from prototyping and model selection through production... 
    Senior

    Take2

    New York, NY
    19 hours ago
  •  ...Capital One is seeking an AI Engineer 5 for the New York, NY area to help scale responsible AI systems. You will partner with cross‑functional teams to design and deploy AI software components, including foundation model training and multi‑agent workflows to improve customer... 
    Senior

    Capital One

    New York, NY
    5 days ago
  • Google's software engineers develop the next-generation technologies that change how billions of users connect, explore, and interact with information and one another. Our products need to handle information at massive scale and extend well beyond web search. We're looking... 
    Senior

    Google

    New York, NY
    15 hours ago
  •  ...Probook in New York, NY is building an AI operating system for home services. You will own the developer and infrastructure layers that power...  ...end-to-end reliability, and collaborating with product engineers and customers to scale the platform. You’ll tackle cost, observability... 
    Senior

    Probook

    New York, NY
    2 days ago
  •  ...Optiver in New York is seeking an experienced AI Engineer to join the Applied AI and Platform Engineering team. You will design, build, and deploy production-grade AI systems that automate workflows, augment decision-making, and accelerate engineering across the firm.... 
    Senior

    Optiver

    New York, NY
    3 days ago
  •  ...Capital One is seeking an AI Engineer 5 for Gen AI Platform Services: Agentic AI in New York...  ...design, build, test, and productionize AI software components, including LLM inference,...  ...functional teams to deliver scalable AI systems, optimize performance, and contribute to... 
    Senior

    Capital One

    New York, NY
    2 days ago
  •  ...SIDRAM TECHNOLOGIES is seeking a Senior AI / Agent Platform Engineer in New York, NY. The role focuses on building scalable runtime services and distributed systems to power enterprise AI agent capabilities in production environments. The candidate will design and implement... 
    Senior

    SIDRAM TECHNOLOGIES

    New York, NY
    3 days ago
  •  ...Rebar is building the next-generation operating system for HVAC/electrical/plumbing suppliers and subcontractors. We are hiring a Senior ML Infrastructure Engineer to build the platform that ML engineers depend on for rapid iteration, training, evaluation, deployment,... 
    Senior
    For subcontractor

    Rebar

    New York, NY
    5 days ago
  •  ...LG Ad Solutions is seeking a motivated AI Platform Engineer to join our AI team and help build the in-house platform powering generative AI...  ...with services like AWS Bedrock and vector stores, instrument systems for observability and tune for latency, throughput and cost.... 
    Senior
    Relocation

    LG Ad Solutions

    New York, NY
    3 days ago
  •  ...Scale AI, Inc. is building an orchestration platform to run durable, scalable workflows...  ...across product and data teams. As a Senior Software Engineer, you will shape the primitives,...  ...native tech to deliver reliable, scalable systems that power Scale's AI #J-18808-Ljbffr... 
    Senior

    Scale AI

    New York, NY
    4 days ago
  • $194k - $349k

     ...world’s most advanced AI-native platform. We work...  ...large scale distributed systems, processing almost 3...  ...CrowdStrike, Site Reliability Engineering (SRE) is fundamental to...  ...of events/day. As a Senior SRE Manager, you'll...  ...teams ~10+ years of software engineering experience... 
    Senior
    Permanent employment
    Work experience placement
    Work at office
    Local area
    Remote work
    New York, NY
    3 days ago
  •  ...Inc. is seeking an architect-level engineer to design and deliver secure, scalable software frameworks and production code...  ...while advising teams and influencing senior stakeholders on technical...  ...responsible adoption of agentic AI-enabled engineering workflows, establishing... 
    Senior

    JPMorganChase

    New York, NY
    15 hours ago
  • $178k - $267k

    AlphaSense is looking for a passionate software engineer to join their AI & Search mission in New York. In this role, you'll architect and implement scalable services for AI and search products, improving reliability and cost efficiency. You should have solid back-end... 
    Senior

    BetterCloud

    New York, NY
    4 days ago
  •  ...S&P Dow Jones Indices is seeking a Senior Distinguished Engineer in New York City to lead architecture and technology strategy. You will drive the development of the full technology stack, partnering with product, risk, and compliance teams to ensure market integrity while... 
    Senior

    S&P Global

    New York, NY
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Software Engineer - AI Systems. Be the first to apply!