End to End Project Lead

Location: Vacaville, California (On-site) Relocation assistance is available for eligible candidates and their families, if needed. Reporting to the E2E Program Lead, the End-to-End Project Lead for 1112k / 825k is responsible for planning, managing and delivering the design, construction, commissioning and validation of the existing asset modifications in order to build product-agnostic capabilities for the Vacaville site, ensuring all tech transfers and overall large, complex projects pertaining to the respective asset. The Asset E2E lead has the ownership of the cost, scope and schedule of the projects to achieve their business goals. In line with their strategic, technical and project management responsibilities, the E2E Lead leads all the project functions. What you will get The full-time base annual salary for this position is expected to range between $181,500 to $302,000. In addition, below you will find a comprehensive summary of the benefits package we offer:

• Performance-related bonus
• Medical, dental and vision insurance
• 401(k) matching plan
• Life insurance, as well as short-term and long-term disability insurance
• Employee assistance programs
• Paid Time Off

Key responsibilities:

• Strategic Project Execution: Define scope and goals with stakeholders, ensuring projects align with market strategy and economic justification.
• Engineering Design & Delivery: Translate requirements into technical design inputs to meet cost, timeline, and functionality targets.
• PM Framework & Governance: Partner with sponsors to establish contractual frameworks and manage scope changes with Engineering leadership.
• Operational Excellence: Integrate project downtime into master schedules and drive cross-functional validation across CAPEX and procurement.
• Leadership & Development: Build high-performing project teams, offering mentorship and feedback to ensure delivery excellence.
• Communication & Mediation: Facilitate information flow between Global Engineering and steering committees, mediating technical or logistical hurdles.
• Regulatory & Compliance: Lead operational readiness and mitigation plans to ensure cGMP compliance and successful regulatory approval.

Key requirements :

• Bachelor’s degree in Life Science, Engineering or Business Management. Master’s degree preferred.
• Demonstrated success in operational management, PMP Project Manager Certification, 6S and Lean Manufacturing, Lean Six Sigma green belt or black belt is preferred.
• 10+ years of experience in Manufacturing /operations role within the pharmaceutical, biopharmaceutical, or a similar regulated industry.
• Data driven decision maker and problem solver, with strong problem-solving skills.
• Understanding of operational excellence, including continuous improvement methodologies (e.g. Lean, Six Sigma, etc.)
• Strong understanding of and proven experience with cGMP requirements for biologics manufacturing.

About Lonza At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of. Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. Ready to shape the future of life sciences? Apply now.