Senior Scientist II, Occupational & Environmental Toxicologist
AbbVie
About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube. Job Description Genetic, Environmental, and Occupational Toxicology (GEO Tox) is a diverse team of scientists with the goals of supporting patient, environmental, and employee safety. The candidate will complete risk assessments supporting occupational, environmental, manufacturing, and regulatory filings. The position will support programs across AbbVie’s therapeutic areas and involve a broad range of modalities across all stages from early discovery throughout development to marketed products. This is an onsite role based out of the South San Francisco, CA location. Responsibilities Critically evaluate literature and toxicology reports/summaries and utilize tools such as read‑across and in silico data to generate toxicology product risk assessments. This includes toxicology support for extractables and leachables, health‑based exposure limits (HBELs) including permitted daily exposure limits (PDEs) and occupational exposure limits (OELs), environmental risk assessments (ERA), and other contaminants. Successful collaboration with multi‑functional teams to align on safety banding for implementation throughout the company. Engage in related external working groups to help drive industry standards and stay informed of upcoming regulations. Provide guidance and mentorship to junior team members in GEO Tox and adjacent departments. Plan and monitor studies at contract research organizations (CROs) for environmental assessments to support regulatory filings. Plan and monitor studies at contract research organizations (CROs) for worker safety studies to occupational safety and handling. Support evaluation/implementation of relevant new approach methodologies (NAM) Provide technical support for occupational health (hazard) categorizations and chemical registrations, including Globally Harmonized System of Classification and Labelling of Chemicals GHS/CLP, and Safety Data Sheets (SDS). Qualifications Sr. Scientist II Qualifications: Bachelor’s Degree in toxicology or related discipline and typically 12 years of experience OR Master’s Degree in toxicology or related discipline and typically 10 years of experience OR PhD in toxicology or related discipline and typically 4 years of experience. Proven record of successfully evaluating safety risks. Excellent collaboration, multi‑tasking, and communication skills. Excellent oral and written communication and attention to detail. Ability to work in a fast‑paced environment and meet project deadlines. Desired skills Occupational Exposure Banding, Performance‑based exposure control limits, or evaluating toxicity data for Safety Data Sheets. Risk assessment authoring. In depth knowledge and experience with regulatory guidance, i.e., ICHQ3C, ICHQ3D, ICHQ3E, ICHM7, ISO-10993-X. Toxicity data mining in databases and literature. Broad range of software proficiency as well as in silico predictive tools for toxicity, i.e., QSAR, OECD. Board‑certification preferred but not required. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short‑term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: #J-18808-Ljbffr AbbVie
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