Associate Director/Director, Medical Affairs - Publications

Associate Director/Director, Medical Affairs – Publications

San Francisco, CA or Remote or Hybrid

About us:

Braveheart Bio is a clinical-stage biopharmaceutical company focused on developing therapies for patients with hypertrophic cardiomyopathy (HCM) and other serious cardiovascular diseases. Our lead product candidate, BHB-1893, is a next-generation oral small-molecule cardiac myosin inhibitor (CMI) being developed for the treatment of obstructive HCM (oHCM) and non-obstructive HCM (nHCM). Braveheart’s goal is to improve the treatment options for these patients by enhancing speed of onset, depth of gradient response, systolic safety, reversibility and reducing prescribing complexity.

With a proven leadership team, a strong financial foundation, and a high-value late-stage asset, Braveheart Bio represents an outstanding opportunity for ambitious, mission-driven professionals to make a tangible impact in a high-profile and rapidly evolving therapeutic area.

The role:

Position reports to the Head of Medical Affairs. This individual will own the publications function for BHB-1893, leading the strategy, planning, and execution of a multi-year publication and congress plan that builds the body of evidence supporting the global development and future launch of BHB-1893 for obstructive and non-obstructive hypertrophic cardiomyopathy (oHCM and nHCM). This is a highly cross-functional and hands‑on role that will serve as the central point of coordination for the publications strategy and execution. The individual will drive publications from concept through submission and publication, ensuring alignment, scientific quality, and timely delivery across the portfolio. This role will also be responsible for medical affairs reactive scientific communications supporting the global development and future launch of BHB-1893 for hypertrophic cardiomyopathy (HCM). All activities will reflect the highest standards of scientific integrity and remain fully compliant with GPP, ICMJE, and applicable regulatory and industry guidelines.

Key responsibilities:

• Develop, own, and maintain the integrated strategic publication plan (including congress disclosures)
• Identify and prioritize publication opportunities across the full evidence lifecycle: clinical (Phase 1–3, long-term extension, subgroup, and pooled analyses), clinical pharmacology (PK/PD, PopPK, DDI, ethno-bridging), nonclinical/mechanistic, HEOR, disease-state and review articles, and real-world evidence.
• Define journal and congress targeting strategies, including late-breaking submissions and simultaneous publications timed with major data presentations.
• Maintain a backlog of future publication concepts and track emerging data to ensure no key dataset goes unpublished.
• Lead abstract, poster, oral presentation, and manuscript development for major cardiovascular and HCM congresses (e.g., ACC, AHA, ESC, ESC-HFA, HCMS, CVCT, HCM Summit) and relevant specialty meetings.
• Manage submission calendars and deadlines, ensuring on‑time delivery of high‑quality, data‑driven materials.
• Plan publications around key data readouts and topline disclosures, coordinating timing with Corporate Communications and Investor Relations
• Monitor competitive readouts and the external scientific landscape to inform timing, positioning, and messaging of BHB-1893 data.

Cross-functional & external collaboration

• Serve as the publications lead on cross‑functional teams, partnering closely with Clinical Development, Biostatistics and Programming, Clinical Operations, Clinical Pharmacology, Nonclinical, Regulatory, HEOR, Legal and Compliance, and Commercial (within appropriate boundaries)
• Work with Biostatistics and Clinical teams to align publication timelines with database locks, data cuts, and TFL availability.
• Collaborate with our licensing partner, Hengrui Pharma, to coordinate joint publications, data sharing, authorship, and alignment.
• Engage investigators, steering committee members, and external authors to lead or co‑author publications, facilitating author meetings and review cycles.
• Ensure consistent scientific messaging across publications, medical communications, field medical materials, and training.
• Lead the development and maintenance of reactive scientific content, including slide decks, FAQs, standard response documents (SRDs), and other materials to address unsolicited scientific inquiries and emerging medical needs.
• Partner cross‑functionally with Medical Affairs, Clinical Development, Biostatistics, Regulatory, Legal, and Compliance to ensure scientific accuracy, consistency, and appropriate review.
• Work closely with Field Medical and other internal stakeholders to identify content needs, incorporate insights, and prioritize content development.
• Ensure content is evidence‑based, appropriately balanced, and aligned with the scientific narrative and available clinical data.
• Coordinate content review, approval, version control, and periodic updates to ensure materials remain accurate and current.

Governance, compliance & operations

• Build and implement the publications infrastructure, including SOPs, a publication steering committee, review and approval workflows, and a publication management system (e.g., Datavision, PubStrat, iEnvision, or Veeva)
• Ensure all publications adhere to GPP, ICMJE, CONSORT, and company policies, including authorship criteria, disclosure of conflicts of interest, transparency, and audit‑ready documentation.
• Select and/or manage publication and medical writing agencies, overseeing scope, timelines, quality, and budget.
• Develop and track publications metrics and report progress to cross‑functional stakeholders.
• Contribute to broader Medical Affairs activities as needed, including advisory boards, scientific training, and medical communications.

Required experience & skills:

• Advanced scientific degree (MD, PhD, PharmD, or equivalent)
• Associate Director: 5+ years of publications or scientific communications experience in biotech/pharma or a medical communications agency; Director: 8+ years, including leading publication strategy for a late‑stage or launch asset.
• Proven experience with strategic publication planning and execution across all phases of drug development, including high‑impact journal manuscripts and major congress presentations.
• In‑depth knowledge of GPP, ICMJE, CONSORT, and related guidance for scientific data communication
• Solid understanding of clinical trial design, statistical methods, and clinical data reporting
• Demonstrated success working in a matrixed, cross‑functional environment and influencing without authority.
• Strong scientific writing, editing, and data interpretation skills, with the ability to translate complex data into clear, compelling communications.
• Experience managing external agencies, authors, and budgets to deliver projects on time and on budget.
• Excellent organizational and project management skills with the ability to manage multiple concurrent deliverables and deadlines.
• Ability to work independently and collaboratively in a fast‑moving, resource‑lean environment and remain comfortable with change and ambiguity.
• Flexible, proactive, and hands‑on mindset with a roll‑up‑your‑sleeves, can‑do attitude
• Ability to travel domestically and internationally (approximately 15–20%), including to major congresses.

Preferred experience & skills:

• Background or publication experience in cardiovascular medicine, ideally HCM, heart failure, or cardiac myosin inhibitors
• Certified Medical Publication Professional (CMPP) certification
• Experience with late‑breaking clinical trial presentations and simultaneous publications
• Experience with global publications involving ex‑US or licensing partners, particularly China‑generated data
• Experience building a publications function or processes at a small‑to‑mid‑size biotech
• Familiarity with HEOR/RWE publications and clinical pharmacology data
• Hands‑on experience with publication management platforms

Base Salary Range: $175,000 - $245,000

This role is also eligible for a competitive total rewards package, which may include an annual bonus, equity, and a comprehensive benefits offering.

We are an equal opportunity employer.

We are committed to inclusion and diversity, and we do not discriminate on the basis of race, gender, religion, gender, sexual orientation, age, color, marital status, veteran status, disability status, national origin, or any characteristic protected under applicable law.

Braveheart participates in the federal E-Verify program to confirm employment authorization for all new hires.

To learn more about E-Verify please review this poster .