Bioinformatician - Genetics & Bioinformatics

Lincoln Building
Pathology
Shift
Full time
Starting pay is based on experience, skills, and equity; shift, on-call, or weekend differentials) and benefits may apply. At Cincinnati Children's, bioinformatics plays a critical role in advancing precision medicine, accelerating scientific discovery, and improving outcomes for children and families. As a Bioinformatics Analyst I, you will contribute to the development, implementation, and continuous improvement of bioinformatics solutions that support both clinical and research initiatives. Working in close partnership with clinicians, researchers, laboratory professionals, pathologists, and technology teams, you will help curate, analyze, validate, and interpret complex biomedical and genomic data while supporting the development of next-generation sequencing (NGS) pipelines, computational workflows, and software solutions. Through collaboration, innovation, and data-driven problem solving, you will help optimize bioinformatics processes, support clinical accreditation requirements, and contribute to scientific publications and emerging technologies that drive the future of pediatric healthcare.
Relocation assistance may be available for qualified candidates, at the discretion of the hiring department.
Curates, annotates and organizes various types of biomedical data (e.g., flat files, relational and non-relational databases).
Collects and records appropriate metadata.
Ensures data are securely stored yet highly accessible to authorized users.
Data Analysis
Executes pipelines for curating, processing and analyzing biomedical data of various types (e.g., Utilizes existing software to support complex data management tasks (e.g., Utilizes web-based bioinformatics tools and public/proprietary relational databases.
Works in collaboration with both technology and scientific teams.
Develop and maintain novel NGS data analysis algorithms and NGS bioinformatics pipelines.
Comprehensive evaluation of open-source algorithms/tools for DNA and RNA sequence data analysis for building clinical bioinformatics pipeline.
Performs comprehensive validation and documentation of bioinformatics pipelines and algorithms in compliance with clinical accreditation requirements.
Gathers, analyzes, and documents complex clinical and user requirements, functional requirements, and data specifications.
Designs, writes and documents technical specifications to design or redesign complex bioinformatics workflows.
Software Evaluation & Development
Contributes to the evaluation and development of software solutions to support basic to moderately complex data workflows.
Under general supervision, assists with implementation and testing efforts.
Utilizes project and time management skills to complete projects within specific timeframes.
Prepares timelines, project plans and flow charts for the development or enhancement of new and existing genomics applications.
Works in conjunction with laboratory director, pathologists, laboratory professionals, and other scientific members to optimize and validate new analytical tools and processes.
Collaborates with other software developers, institutional IT teams, applications staff and users of information systems to evaluate, plan, design, develop, test, implement, and maintain application development efforts and/or reports.
Contributes to analyses and publications.
Assists with materials for publications and scientific meetings.
Works closely with biostatisticians on the production of publication and presentation materials.
Bachelor's degree in a related field.
~0+ years of work experience in a related job discipline.

Masters' or PhD degree in Bioinformatics.
Proficiency with one or more of the following programming languages:
Python (required)

C/C++

Proficiency using Linux operating systems, command-line tools, and Bash scripting.
Experience utilizing High Performance Computing (HPC) or similar resources for high-throughput computing.
Experience applying artificial intelligence and machine learning techniques to solving complex bioinformatics and genomics problems.
Experience with data visualization and data summarization.
Familiarity designing and maintaining SQL databases (e.g., PostgreSQL, MySQL).
Experience working with genomic, sequencing, clinical, imaging, or other biomedical datasets.
Demonstrated ability to collaborate effectively with multidisciplinary clinical, research, and technology teams.
Passion for learning emerging technologies and advancing computational solutions that support pediatric research and precision medicine.
At Cincinnati Children's, we come to work with one goal: to make children's health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. If you want to be the best you can be, you can do it at Cincinnati Children's.

Cincinnati Children's is:
News & World Report as a top 10 best Children's Hospitals in the nation for more than 15 years
Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH) Funding
Recognized as one of America's Best Large Employers (2025) , America's Best Employers for New Grads (2025)
A Leading Disability Employer as noted by the National Organization on Disability
We believe in empowering our teams with the tools that help us work smarter and care better. That's why we support the responsible use of artificial intelligence. Cincinnati Children's is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/Veteran/Disability