Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Registered Nurse (Rn), University Hospital, Full-Time, Nights

Dukehealth.org

At Duke Health, we're driven by a commitment to compassionate care that changes the lives of patients, their loved ones, and the greater community. No matter where your talents lie, join us and discover how we can advance health together.
About Duke University Hospital
Pursue your passion for caring with Duke University Hospital in Durham, North Carolina, which is consistently ranked among the best in the United States. The largest of the four Duke Healthhospitals with 1062 patient beds, it features comprehensive diagnostic and therapeutic facilities, including a regional emergency/trauma center, an endo-surgery center, and more.
Duke Nursing Highlights:

Duke University Health System is designated as a Magnet organization
Nurses from each hospital are consistently recognized each year as North Carolina's Great 100 Nurses.
Duke University Health System was awarded the American Board of Nursing Specialties Award for Nursing Certification Advocacy for being strong advocates of specialty nursing certification.
Duke University Health System has 6000 + registered nurses
Quality of Life: Living in the Triangle!
Relocation Assistance (based on eligibility)
Registered Nurse (Experienced RN) – Full Time
Duke University Health System Float Pool – Intermediate/Stepdown Units
Earn a $5/hour Float Pool premium while expanding your clinical expertise across multiple specialties.
Why Join Duke Health’s Float Pool?
If you’re an experienced RN looking to grow, diversify your skillset, and work across high-acuity specialties, the Duke Health Float Pool offers a unique and rewarding career path. You’ll gain exposure to a wide variety of patient populations while working alongside top clinical teams across the health system—all while earning a competitive float premium and receiving full benefits.
This role supports patient care across:

Duke University Hospital
Duke Regional Hospital
Duke Raleigh Hospital (a campus of Duke University Hospital)
Clinical Areas Supported
As part of the Intermediate/Stepdown Float Pool, you’ll provide care across diverse specialties, including:

Cardiology & Cardiac Surgery
General Medicine
General Surgery
Neurology & Neurosurgery
Oncology
Orthopedics
Transplant
Trauma
About the Role
Float Pool nurses are highly adaptable clinicians who thrive in dynamic environments. With comprehensive cross-training and ongoing support, you’ll build advanced clinical capabilities and confidence caring for a wide range of patient populations.
Unlike many systems, Duke offers full benefits and career advancement opportunities equal to those of unit-based staff , making this an exceptional opportunity to grow while maintaining stability and support.
What You’ll Do

Deliver high-quality, patient-centered care across Intermediate and Stepdown units
Collaborate with interdisciplinary teams and actively participate in patient rounds
Manage patient assignments with ratios typically ranging from 1:3 to 1:6 , based on acuity
Utilize critical thinking to adapt care plans across different clinical settings
Support a care environment staffed with Charge Nurses, Nursing Care Assistants, and Health Unit Coordinators
As a Clinical Nurse , you will:

Plan, deliver, and evaluate nursing care using the nursing process
Delegate and supervise care team members appropriately
Serve as a preceptor and mentor to peers and learners
Participate in quality improvement and professional development initiatives
Ensure compliance with all regulatory and professional standards
Who We’re Looking For
We’re seeking experienced RNs who:

Thrive in fast-paced, team-oriented environments
Demonstrate adaptability, accountability, and strong clinical judgment
Are passionate about patient advocacy and family-centered care
Align with Duke Health’s mission: Advancing Health Together
Embrace our culture commitments: Putting People First, Being Clear, Empowering Others, and Adapting to Improve
Work Schedule

Shifts: Days (7A–7P), Nights (7P–7A), or rotating
Schedule Options:
Three 12-hour shifts/week, OR
Alternating 3 shifts one week / 2 shifts the next

Weekend Rotation: One Monday, Friday, Saturday, and Sunday per 4-week schedule
Holidays: One major and one minor holiday for both winter and summer seasons
Weekend option roles available
Compensation & Benefits

  • $5.00/hour Float Pool premium
  • Competitive base pay and shift differentials
  • Paid onboarding: ~1 week hospital orientation + ~3 weeks unit-based orientation
  • Career Ladder advancement opportunities
  • PTO accrual and comprehensive benefits (Medical, Dental, Vision)
  • Up to $25,000 in Nurse Loan Forgiveness
  • Tuition assistance and certification bonus
  • Relocation assistance (for moves
  • 50 miles)
  • Employee referral bonus program
  • Duke-funded pension plan (fully vested after 5 years)
  • 403(b) retirement savings plan
  • Ongoing professional development through Duke Continuing Education

Qualifications

Graduate of an accredited ADN, Diploma, or BSN program
Minimum 1 year of recent RN experience (Intermediate/Stepdown or acute care preferred)
Note: RNs without a BSN must enroll in a BSN program within 2 years of hire and complete it within 7 years.
Licensure & Certifications

Active RN license in North Carolina or compact state license
BLS required
ACLS, NIH, CPI preferred
Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Registered Nurse (Rn), University Hospital, Full-Time, Nights in Durham, NC vacancy
  • $1,633 - $1,815 per week

     ...Registered Nurse (RN) | Emergency Room (ER) / Trauma Location: Raleigh-Durham Region, NC Agency: All Medical Personnel Pay: $1,633 to $1,815 per week Contract Duration: 13 Weeks Start Date: ASAP About the Position Specialty: RN-Emergency... 
    Suggested
    Weekly pay
    Full time
    Contract work
    Locum
    Immediate start

    All Medical Personnel

    Durham, NC
    16 hours ago
  • $1,633 - $1,815 per week

     ...Registered Nurse (RN) | Emergency Room (ER) / Trauma Location: Raleigh-Durham Region, NC Agency: All Medical Personnel Pay: $1,633 to $1,815 per week Contract Duration: 13 Weeks Start Date: ASAP About the Position TravelNurseSource is working... 
    Suggested
    Weekly pay
    Full time
    Contract work
    Locum
    Immediate start

    TravelNurseSource

    Durham, NC
    16 hours ago
  •  ...Community-Based Hospice Nurse (RN), PRN Job Category: Community-Based Hospice Nurse Requisition Number: COMMU001080 Part-Time Raleigh, NC 27607, USA +8 more locations Job Details Job Summary This is a PRN professional position. This position provides... 
    Suggested
    Contract work
    Part time
    Relief
    Shift work
    Weekend work

    Transitions LifeCare

    Durham, NC
    1 day ago
  • $1,841.45 per week

     ...exciting Travel Nursing job in Durham, NC. Shift: 3x12 hr nights Start Date: ASAP Duration: 13 weeks Pay: $1841.45 / Week Profession: RN Requirements: BLS;PALS Desired Start Date: 2026-05-18 Facility Type: Magnet and Level I Trauma and Teaching Facility... 
    Suggested
    Flexible hours
    Shift work
    Night shift

    FlexCare

    Durham, NC
    more than 2 months ago
  • $1,777 - $1,977 per week

     ...Registered Nurse (RN) | Intensive Care Unit (ICU) / Critical Care Location: Durham, NC Agency: Ventura MedStaff Pay: $1,777 to $1,977 per week Shift Information: Nights - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: ASAP About... 
    Suggested
    Weekly pay
    Full time
    Contract work
    Immediate start
    Flexible hours
    Shift work
    Night shift

    Ventura MedStaff

    Durham, NC
    16 hours ago
  • $1,714 - $1,904 per week

     ...Registered Nurse (RN) | Intensive Care Unit (ICU) / Critical Care Location: Raleigh-Durham Region, NC Agency: All Medical Personnel Pay: $1,714 to $1,904 per week Contract Duration: 13 Weeks Start Date: ASAP About the Position TravelNurseSource... 
    Weekly pay
    Full time
    Contract work
    Locum
    Immediate start

    TravelNurseSource

    Durham, NC
    16 hours ago
  • $2,265 per week

     ...Registered Nurse (RN) | Intensive Care Unit (ICU) / Critical Care Location: Durham, NC Agency: HPA Healthcare Pay: $2,265 per week Shift Information: Nights - 12 hours Contract Duration: 13 Weeks Start Date: ASAP About the Position... 
    Full time
    Contract work
    Local area
    Immediate start
    Shift work
    Night shift
    Weekend work

    TravelNurseSource

    Durham, NC
    16 hours ago
  • $2,265 per week

     ...Registered Nurse (RN) | Intensive Care Unit (ICU) / Critical Care Location: Durham, NC Agency: HPA Healthcare Pay: $2,265 per week Shift Information: Nights - 12 hours Contract Duration: 13 Weeks Start Date: ASAP About the Position... 
    Full time
    Contract work
    Local area
    Immediate start
    Shift work
    Night shift
    Weekend work

    HPA Healthcare

    Durham, NC
    16 hours ago
  • $1,714 - $1,904 per week

     ...Registered Nurse (RN) | Intensive Care Unit (ICU) / Critical Care Location: Raleigh-Durham Region, NC Agency: All Medical Personnel Pay: $1,714 to $1,904 per week Contract Duration: 13 Weeks Start Date: ASAP About the Position Specialty:... 
    Weekly pay
    Full time
    Contract work
    Locum
    Immediate start

    All Medical Personnel

    Durham, NC
    16 hours ago
  • $1,777 - $1,977 per week

     ...Registered Nurse (RN) | Intensive Care Unit (ICU) / Critical Care Location: Durham, NC Agency: Ventura MedStaff Pay: $1,777 to $1,977 per week Shift Information: Nights - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: ASAP About... 
    Weekly pay
    Full time
    Contract work
    Immediate start
    Flexible hours
    Shift work
    Night shift

    TravelNurseSource

    Durham, NC
    16 hours ago
  • $1,871 per week

     ...Registered Nurse (RN) | Intensive Care Unit (ICU) / Critical Care Location: Durham, NC Agency: Triage Staffing Pay: $1,871 per week Shift Information: Days - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: 7/21/2026 About the... 
    Full time
    Contract work
    Shift work

    TravelNurseSource

    Durham, NC
    3 days ago
  • $1,759 - $1,959 per week

     ...Registered Nurse (RN) | Intensive Care Unit (ICU) / Critical Care Location: Durham, NC Agency: Ventura MedStaff Pay: $1,759 to $1,959 per week Shift Information: Days - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: ASAP About... 
    Weekly pay
    Full time
    Contract work
    Immediate start
    Flexible hours
    Shift work

    TravelNurseSource

    Durham, NC
    16 hours ago
  • $1,871 per week

     ...Registered Nurse (RN) | Intensive Care Unit (ICU) / Critical Care Location: Durham, NC Agency: Triage Staffing Pay: $1,871 per week Shift Information: Days - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: 7/21/2026 About the... 
    Full time
    Contract work
    Shift work

    Triage Staffing

    Durham, NC
    3 days ago
  •  ...Nurse II - Duke Regional Hospital - Endscopy Services Duke University Health System seeks to hire an experienced Registered Nurse (RN) - CN II who will embrace our mission of Transforming Lives Transforming Care. Required:  ACLS certification and at least one... 
    Relocation package
    Monday to Friday
    Shift work
    Weekend work

    Duke University Health System

    Durham, NC
    4 days ago
  •  ...Registered Nurse (RN) Endoscopy Services Work Arrangement: Regular Location: Durham, NC, US, 27710 Personnel Area: DUKE REGIONAL HOSPITAL At Duke Health, we're driven by a commitment to compassionate care that changes the lives of patients, their loved ones, and... 
    Relocation package
    Monday to Friday
    Shift work
    Weekend work

    Duke University

    Durham, NC
    4 days ago
  •  ...Description RN- Registered Nurse - ER- Emergency Room Specialty : ER- Emergency Room Location : Durham,NC,27704 Start Date : 2026-07-13 End Date : 2026-10-10 Duration : 13 Week Shift : 3x12 Job Description... 
    Immediate start
    Shift work
    Night shift

    Alliance Medical Staffing

    Durham, NC
    2 days ago
  • $1,920 per week

    SambaTraveler is seeking an experienced Operating Room Registered Nurse for an exciting Travel Nursing job in Durham, NC. Shift: 5x8 hr days Start Date: ASAP Duration: 13 weeks Pay: $1920 / Week Coast Medical Service is a nationwide travel nursing & allied healthcare...
    Shift work

    SambaTraveler

    Durham, NC
    a month ago
  • $28 - $33 per hour

     ...Angels of Care Home Health is looking for Registered Nurses (RN) and Licensed Practical Nurses (LPN) in Durham, NC and surrounding areas. Pay Range LPN: $28-$33/hr RN: $30-$35/hr Job Duties Focus on the medical needs and treatment of infants, children, and/or adolescents... 
    Weekly pay
    Full time
    Temporary work
    Flexible hours
    Shift work

    Angels of Care Pediatric Home Health

    Durham, NC
    1 day ago
  • $28 - $33 per hour

     ...Description Angels of Care Home Health is looking for Registered Nurses (RN) and Licensed Practical Nurses (LPN) in Durham, NC and surrounding areas. Angels of Care has been caring for the medically fragile community across the nation since 2000! We pride ourselves... 
    Weekly pay
    Full time
    Temporary work
    Part time
    Flexible hours
    Shift work
    Night shift
    Weekend work

    Angels of Care Pediatric Home Health

    Durham, NC
    2 days ago
  •  ...care and established policies and procedures. Provide nursing services to patients and families in accordance with the scope of the RN as defined by the North Carolina Board of Nursing. Work Performed Plan, provide and document professional nursing care, utilizing the... 
    Relocation package

    Direct Jobs

    Durham, NC
    3 days ago
  •  ...Trauma Stepdown 3300 Newly Hired Experienced RNs are eligible for a $15,000 commitment bonus Relocation available for New and Experienced RN Unit Profile The General Surgery & Trauma Stepdown Unit (3300) at Duke strives to provide exceptional care to acutely ill patients.... 
    Relocation
    Relocation package
    Shift work
    Night shift

    Duke University Health System

    Durham, NC
    2 days ago
  •  ...Registered Nurse (RN) Cath Lab Independently plan and provide professional nursing care for patients in accordance with physician orders and established policies and procedures. Provide nursing services to patients and families in accordance with the scope of the RN... 

    Duke University

    Durham, NC
    4 days ago
  •  ...care and established policies and procedures. Provide nursing services to patients and families in accordance with the scope of the RN as defined by the North Carolina Board of Nursing. Work Performed Plan, provide and document professional nursing care, utilizing... 
    Relocation package

    Dukehealth.org

    Durham, NC
    2 days ago
  •  ...orders and established policies and procedures. Provide nursing services to patients and families in accordance with the scope of the RN as defined by the North Carolina Board of Nursing. Work Performed Plan, provide, supervise and document professional nursing... 
    Relocation package

    Dukehealth.org

    Durham, NC
    2 days ago
  • $1,000 per month

    Go further with the best Benefits & Perks Package our industry has to offer. We provide everything you need to ensure you are covered on and off the clock. Day One Health Coverage You are covered on day one when you take a full-time contract with ORNN. Our premium BCBS ...
    Weekly pay
    Full time
    Contract work
    Shift work

    Travel Nurses Inc

    Durham, NC
    4 days ago
  • $2,175 per week

    Cynet Health is seeking an experienced Intensive Care Unit Registered Nurse for an exciting Travel Nursing job in Durham, NC. Shift: 3x12 hr nights Start Date: 07/27/2026 Duration: 13 weeks Pay: $2175 / Week About Cynet Health: Ranked #5 Best Travel Nursing Companies...
    Shift work
    Night shift

    Cynet Health

    Durham, NC
    16 days ago
  • RELOCATE TO VIRGINIA OPPORTUNITY Join our esteemed team of healthcare professionals committed to advancing healthcare through cutting-edge research, comprehensive training, and compassionate care. UVA Health is an integrated health system with a world-class academic...
    Live in
    Local area
    Relocation
    Relocation package

    UVA Health

    Durham, NC
    3 days ago
  •  ...Description RN- Registered Nurse - ICU- Intensive Care Unit Specialty : ICU- Intensive Care Unit Location : Durham,NC,27704 Start Date : 2026-07-27 End Date : 2026-10-24 Duration : 13 Week Shift : 3x12... 
    Immediate start
    Shift work
    Night shift

    Alliance Medical Staffing

    Durham, NC
    4 days ago
  •  ...including orthopedics, weight-loss surgery, women's services, and heart and vascular services. Are you an experienced Operating Room (OR)RN who is seeking greater exposure to a diverse service portfolio? If so, then this is the job for you! We are seeking a Clinical Nurse... 
    Monday to Friday
    Shift work
    Night shift

    Duke Clinical Research Institute

    Durham, NC
    1 day ago
  •  ...planning and supervising nursing care, monitoring patient needs, and ensuring a safe environment. The candidate must hold a current RN licensure in North Carolina and possess at least one year of clinical experience. This position offers the opportunity to contribute... 

    Duke Clinical Research Institute

    Durham, NC
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Registered Nurse (Rn), University Hospital, Full-Time, Nights. Be the first to apply!