Research Fellow (Remote)

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

Join our Artificial Intelligence-Powered Lab (AIPL), an initiative at the intersection of academic creativity and start-up style execution. Our mission is to apply machine learning to biological design. Join us as we build a series of interconnected design-test-loop “flywheels” that enable design of synthetic enhancers, protein binders, and more.

AIPL is looking for a research associate to join our protein binder flywheel team. The binder flywheel team is part of a larger effort that includes a total of three experimental flywheel teams and one machine learning team, and that will report into the SeaHub administrative unit. You will work in the lab to optimize active learning processes in your flywheel. You will help to optimize your flywheel’s turn‑around‑time and per-cycle model improvement, racing to help deliver the best possible ML models for predicting the impact of mutations on protein binding.

At the Allen Institute, we believe that science is for everyone - and should be open to everyone. We also believe that science is better when it includes different perspectives and voices. Perform protein library screening and binder evaluation experiments to generate high‑quality, model‑ready datasets

Execute binder screening protocols, including molecular cloning, CLICK/Phage display, FACS, and NGS library preparation and sequencing

Assist in troubleshooting technical barriers in the generation of high‑quality data, from library cloning to delivery to FACS to NGS library generation

Review and analyze data, participating in quality control and troubleshooting of processes and results

Present results and summarize progress to help frame internal decision‑making

Comply with SOPs, good laboratory practices, and regulatory requirements

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Bachelor’s Degree in biochemistry, molecular biology, or a related field

yeast/phage display + FACS/NGS or other high‑throughput binder discovery platforms)

Experience performing molecular biology methods including molecular cloning (such as restriction cloning, Gibson Assembly, Golden Gate assembly, plasmid prep)

RNA isolation, DNA isolation, and PCR

Competence and ability to work in a molecular biology/cell culture laboratory

Experience performing cell biology methods including mammalian cell culture, murine embryonic stem cell culture, primary cell culture, nucleofection, and lipofection

Fine motor movements in fingers/hands to operate computers and other office/lab equipment

Possible exposure and handling of laboratory animals

Laboratory atmosphere - possible exposure to chemical, biological or other hazardous substances

any remote work must be performed in Washington State

Travel
The successful candidate may be invited to attend occasional national and international conferences

These benefits include medical, dental, vision, and basic life insurance. It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.

#J-18808-Ljbffr ClearCompany Talent Management Software