Systems Engineering, Design & Development

Job Title: Systems Engineer II

Location: Santa Clara, CA 95050 (Onsite)

Duration: 12 Months with strong possibility of extension

Job Description:
The Sequencing team is seeking a passionate Systems Engineer II to join the Systems Integration Group supporting Next Generation Sequencing (NGS) products. This is a hands-on role in which the Systems Engineer II will contribute to feasibility, development, and integration activities for end-to-end NGS solutions.
As a member of the Systems Integration team, this individual will work with a Single Molecule Sequencing platform to optimize operating protocols, design and perform wet-lab experiments, support integration of system subcomponents, and help improve the overall sequencing solution.

Key Responsibilities
Design, execute, analyze, and document experiments to support feasibility, development, integration, verification, and validation of NGS workflows.
Perform sample preparation, library preparation, sequencing-related experiments, and verification studies.
Use the Single Molecule Sequencing platform to optimize final operating protocols and support system-level integration activities.
Interpret experimental results using appropriate experimental design and statistical analysis methods.
Troubleshoot instrument, workflow, or assay-related failures using standard root cause analysis methods.
Collaborate with subject matter experts to understand failure modes and identify appropriate solutions.
Develop, execute, and document test cases based on product requirements for verification and validation activities.
Maintain accurate, well-organized, and concise laboratory records using best laboratory practices.
Work cross-functionally with assay, instrumentation, software, bioinformatics, and systems teams to resolve integration challenges.
Support continuous improvement of sequencing performance, including coverage, throughput, robustness, reproducibility, and overall system reliability.
Required Qualifications
Bachelor's degree in chemistry, science, engineering, or a related field with 5 years of relevant experience, or a Master's degree in a related field with 1-3+ years of relevant experience.
Demonstrated hands-on experience with PCR, DNA sequencing methods, raw sample preparation, nucleic acid extraction, library preparation, and/or NGS sequencing.
At least 2 years of experience using MATLAB, Git, Python, or similar tools for data analysis and/or automation.
Experience with statistical tools and methods, such as Python, JMP, regression analysis, and ANOVA.
At least 2 years of experience with Design of Experiments methodology and application of statistical process control.
Demonstrated ability to troubleshoot technical issues and identify root causes in laboratory, instrument, or workflow settings.
Strong documentation skills and commitment to following best laboratory practices.
Preferred Qualifications
Proven track record of performing in a fast-paced, matrixed environment.
Ability to work independently while collaborating effectively across functions.
Demonstrated ability to influence technical decisions and stakeholders without direct authority.
Experience solving unique, ambiguous, or unpredictable problems that may impact project or organizational goals.
Strong planning, prioritization, multitasking, and follow-through skills.
Highly energetic, focused, and adaptable working style.
Strong interpersonal, verbal communication, and relationship-building skills.
Demonstrated ability to build and maintain effective relationships with key stakeholders.
You will receive the following benefits:

• Medical Insurance - Four medical plans to choose from for you and your family
• Dental & Orthodontia Benefits
• Vision Benefits
• Health Savings Account (HSA)
• Health and Dependent Care Flexible Spending Accounts
• Voluntary Life Insurance, Long-Term & Short-Term Disability Insurance
• Hospital Indemnity Insurance
• 401(k) including match with pre and post-tax options
• Paid Sick Time Leave
• Legal and Identity Protection Plans
• Pre-tax Commuter Benefit
• 529 College Saver Plan

Motion Recruitment Partners (MRP) is an Equal Opportunity Employer. All applicants must be currently authorized to work on a full-time basis in the country for which they are applying, and no sponsorship is currently available. Employment is subject to the successful completion of a pre-employment screening. Accommodation will be provided in all parts of the hiring process as required under MRP's Employment Accommodation policy. Applicants need to make their needs known in advance.
Specialization :
~ System Administration