Senior Software Engineering - Machine Learning

Department: Engineering

BigHat Biosciences is looking for a Senior Software Engineer to join our engineering team. This role is for experienced engineers ready to own a significant area of our platform as a subject‑matter expert, lead epics end‑to‑end, and shape the architecture and engineering practices that support the design, build, and testing of therapeutic antibodies at scale. You will work closely with engineers, product partners, and laboratory scientists to build and evolve the internal software systems at the center of our science.

This role is leveled as Senior Software Engineer I. At this level, you operate as a subject‑matter expert in your area, working with a high degree of independence and regularly leading epics. Candidates with prior experience in biotech, life sciences, or scientific software may be considered with fewer total years of software engineering experience.

Lead projects end‑to‑end, from PRD through implementation, testing, release, and validation against the customer success metric.

Own one or more major areas of BigHat's internally developed, cloud‑based platform as a subject‑matter expert, and serve as a cross‑team and cross‑org resource for those areas.

Take on net‑new, 0‑to‑1 work from specification, designing interactions between features and the infrastructure that supports them, and producing novel solutions where existing patterns fall short.

Collaborate with, and increasingly manage, the relationship with scientists and product owners to translate real‑world lab workflows into reliable software, and to iterate on success metrics.

Own the quality and outcomes of your work and your epics, including debugging, test failures, and production issues, anticipating next steps and owning the trajectory of major features.

Design and build high‑quality software across front‑end (UI/UX) and back‑end systems, with system‑level expertise in the databases, AWS services, runtimes, and processes that underpin them.

contribute architectural direction and surface risks and tradeoffs early.

Write, maintain, and raise the bar on automated testing to ensure correctness, reliability, and maintainability.

help set and transmit appropriate urgency in partnership with engineering leaders.

You have a track record of owning features and epics end to end in a production software environment.

You work highly independently and initiate the collaborations needed to deliver work that bridges many parts of the codebase.

You balance development, architecture, and process effectively, and help the team prioritize where effort yields the most impact.

You communicate clearly about progress, risks, and tradeoffs, and your own outcomes, following issues through to resolution and validating that you've met the customer's needs.

You are motivated by building software that supports real users doing complex, high‑stakes scientific work.

You adapt well as priorities and focus areas shift, and you collaborate effectively with engineers inside and outside your direct team.

7+ years of professional software engineering experience building and owning production systems, including demonstrated end‑to‑end ownership of features or epics, OR

5+ years of professional software engineering experience with prior experience in biotech, life sciences, laboratory environments, or scientific software, where domain knowledge meaningfully accelerates impact.

TypeScript, React, Material‑UI, Vega

Python 3, SQLAlchemy

AWS (CDK, Lambda, Step Functions, ECS/Batch, Fargate, API Gateway, Athena)

Relational databases (e.g., PostgreSQL), including schema and query design

PyTorch or other ML frameworks (nice to have, not required)

The salary estimated for this position is $198,00 - $215,000 + bonus + options + benefits. Actual compensation will be confirmed in writing at the time of the offer.

Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)

Dental, and vision coverage through Guardian

DTO, two weeks of company‑wide shutdown, and 12 company holidays