Post Doc Research Fellow Lab

We are recruiting a highly motivated and creative postdoctoral fellow to develop next-generation protein-based immunotherapies for cancer and autoimmune diseases.
The Rashidian Lab at Dana-Farber Cancer Institute and Harvard Medical School is an interdisciplinary research group working at the interface of protein engineering, immunology, and therapeutic development. Our research focuses on designing innovative protein-based technologies to manipulate immune responses, enhance the efficacy and durability of cellular immunotherapies, and develop new therapeutic strategies for cancer and autoimmune diseases.
Building on our recent discoveries in engineered immunotherapies and immune signaling, we are launching exciting new projects with significant potential for biological discovery and clinical translation. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The successful candidate will lead an innovative research project focused on the design, engineering, and functional characterization of novel protein-based immunotherapeutics. The position offers substantial scientific independence, opportunities to develop new therapeutic concepts, and close collaboration with experts in immunology, protein engineering, cancer biology, and clinical oncology.
We particularly encourage applications from PhD candidates approaching their dissertation defense and scientists who have recently completed their PhD.
A PhD (or anticipated PhD) in protein engineering, immunology, molecular biology, bioengineering, or a related discipline.
Strong research experience in protein engineering and/or immunology .
Experience with recombinant proteins, antibody engineering, molecular biology, cellular immunology, or related techniques.
A strong publication record appropriate to career stage, scientific creativity, and enthusiasm for developing new therapeutic approaches.
We are particularly interested in outstanding candidates who bring deep expertise in either field and are excited to expand their skills.
This is an opportunity to lead ambitious, high-impact research in a collaborative and scientifically stimulating environment. Our laboratory combines fundamental mechanistic discoveries with therapeutic engineering and translational research, providing an excellent setting for scientists interested in developing innovative medicines.
Nature Biotechnology (2024). A CAR enhancer increases the activity and persistence of CAR T cells. Antigen-IL-2 CAR-enhancer drives CAR-T fate and stemness, enhancing antitumor efficacy across models independent of IL-2Rα. Science Translational Medicine (2025). Antigen-Fc fusion therapy reduces severity of a model of pemphigus vulgaris without systemic immunosuppression. edu with their CV, a brief description of their research experience and interests, and contact information for three references.
Learn more about our research:
We welcome applications from enthusiastic scientists who are excited to push the boundaries of protein engineering and immunotherapy.
As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
. The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
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