Senior Software Engineer

About ProsciaProscia is revolutionizing pathology, the last major frontier in healthcare to embrace digital. As a leader in pathology AI software, we are empowering pathologists and scientists to transition from traditional microscope-based workflows to digital, AI-driven approaches, unlocking new possibilities in precision medicine.The digital pathology market is experiencing explosive growth as advances in AI enable unprecedented insights into diseases like cancer. Pathology is central to medicine, and the shift to AI-powered solutions is not just modernizing workflows—it’s transforming how diseases are diagnosed, treated, and understood. Predictions for the future of pathology show a tidal wave of adoption, with experts describing the field as “poised for the next major breakthrough” in healthcare innovation.Backed by over $100 million in funding from leading healthcare and technology investors, Proscia is at the forefront of this revolution. Joining Proscia means being part of a company at the cutting edge of healthcare innovation, where the possibilities are limitless. With the convergence of AI, precision medicine, and digital pathology, we’re not just changing pathology—we’re redefining what’s possible in medicine.About the RoleAs a Senior Software Engineer, you’ll help build and evolve the software platform powering the future of digital pathology and medical imaging. You’ll work across the application stack — from scalable backend services and APIs to modern web applications and cloud-native infrastructure — delivering enterprise-grade software used in real-world healthcare environments.We’re looking for an engineer who is equally comfortable designing distributed systems, building intuitive user experiences, and leveraging modern AI-assisted development workflows. You’ll collaborate closely with cross-functional engineering, product, and operations teams to deliver highly scalable, reliable, and maintainable solutions.Our platform combines high-performance medical imaging, modern web technologies, microservices architecture, and cloud-native infrastructure to solve meaningful problems in healthcare and diagnostics.The ideal candidate has strong experience with TypeScript, Node.js/Deno, PostgreSQL, modern frontend development (Vue preferred), automated testing, and service-oriented architectures — along with a passion for building high-quality software and continuously improving engineering practices.Key ResponsibilitiesDesign, develop, test, and deploy scalable services and applications across the platform stackBuild and maintain modern APIs, microservices, and web applications using TypeScript and VueCollaborate within a high-performing Agile/Scrum team to define, estimate, and deliver impactful featuresPartner with engineering teams across Proscia to ensure interoperability, platform consistency, and shared architectural directionContribute to frontend architecture and user experience improvements for complex, data-intensive applicationsAdopt an AI-first mindset by integrating modern intelligent tools into your engineering workflows for system navigation, configuration validation, and complex troubleshooting. We expect our engineers to already be leveraging these technologies as a core part of their professional practice.Demonstrated experience developing with large language models, agentic pipelines, or AI agents, along with a proven track record of applying advanced AI-assisted development techniques to solve sophisticated technical challenges.Fluency in prompt engineering, tool-use patterns, and the evaluation of AI systems, including the ability to identify necessary guardrails and ensure the reliability of AI-generated technical outputs.Participate in architectural design discussions and help drive best practices for scalability, observability, maintainability, and performanceImprove developer productivity through automation, testing, CI/CD, and platform toolingContinuously evaluate emerging technologies, frameworks, and engineering practices to improve the platformRequired Experience5+ years of professional software engineering experience building production-grade applicationsStrong experience with TypeScript and Node.js/Deno in enterprise application environmentsExperience building and maintaining RESTful APIs and service-oriented applicationsExperience developing modern web applications using Vue.js or comparable frontend frameworks such as React or AngularStrong understanding of distributed systems, microservices, and API-driven architecturesExperience working with PostgreSQL in production environments, including ORM usage and direct SQL optimizationStrong automated testing experience using frameworks such as Vitest and PlaywrightExperience building and deploying cloud-native applications in AWS or AzurePrior experience with containerization and orchestration technologies such as Docker and KubernetesExperience with CI/CD pipelines and modern software delivery practicesFamiliarity with Git-based workflows and Agile/Scrum development methodologiesExcellent problem-solving, communication, and collaboration skillsPassion for delivering high-quality, maintainable, and observable software systemsDesirable ExperienceExperience designing and scaling distributed systems in production environmentsPractical experience with microservices architecture and understanding associated trade-offsExperience building highly interactive or data-intensive frontend applicationsFamiliarity with medical imaging, healthcare software, or regulated environmentsExperience working with large-file or high-throughput systems such as image processing or streaming platformsUnderstanding of event-driven architectures and messaging systems such as RabbitMQ, Kafka, or AWS SQSExperience with caching strategies, load balancing, API gateways, and performance optimization techniquesKnowledge of database optimization strategies including indexing, partitioning, and connection poolingExperience with observability and monitoring tools for logs, metrics, and distributed tracingFamiliarity with infrastructure as code tools such as Terraform or CloudFormationExperience participating in architectural reviews and translating technical designs into implementation plansExperience mentoring engineers and contributing to engineering culture and standardsBeyond Just WorkAs a company in healthcare, we want our people to be happy and healthy, in and out of the office. In addition to competitive pay, we ensure everyone on our team is supported with savings, schedule, and insurance options that promote long-term health and personal growth.Our office environment is designed for creativity and agility: with walls as notepads and couches for collaboration. We’re located in the heart of Philadelphia, with views of the city so you can spend your time focusing on what matters most.At Proscia, we don’t just accept differences — we celebrate them, we support them, and we thrive on them for the benefit of our employees, our products, and our community. Proscia is proud to be an equal opportunity workplace.Why This Role MattersAt Proscia, we’re transforming pathology through software, AI, and modern medical imaging technology. You’ll work on meaningful technical challenges involving cloud-native systems, enterprise applications, high-performance image workflows, and modern web platforms — all while helping advance the future of precision medicine and diagnostics.DepartmentTechnologyEmployment TypeFull-TimeMinimum ExperienceExperienced