Research Technician II - Pathology & Immunology

Position Summary The Ackerman lab (Department of Pathology and Immunology, Center for Brain Immunology and Glia) studies molecular mechanisms underlying neural plasticity and neurodegeneration using zebrafish and fruit fly model systems. We use traditional and cutting‑edge genetic strategies to identify new mechanisms used by glial cells (astrocytes, oligodendrocytes, and microglia) to sculpt brain wiring, and to understand how this contributes to a variety of neurological diseases. With the support of a new award from the Hope Center for Neurological Disorders, and as an active collaboration with the lab of Dr. Elizabeth Pollina, the Ackerman lab has recently expanded its scope to explore how neuronal activity influences gene expression and genome architecture in astrocytes. Candidates should have educational or training experience in the biological sciences, and an enthusiasm for new challenges and opportunities. Additional Details about the Lab Our laboratory uses animal models (zebrafish and Drosophila) to understand how the brain develops and functions. The goal of our research is to explore how neuronal activity influences astrocyte genome remodeling and its connection to long‑term brain health. We utilize reverse genetics, optogenetics, next generation sequencing, confocal microscopy, and behavioral readouts to interrogate the nervous system. Primary Duties & Responsibilities Assists with research studies, experiments and assays, including collection of data, preparation of solutions and setup and maintenance of equipment. Performs data entry and maintains data files on research. Prepares tissue cultures, reagents, probe tests, etc. Complies with established safety procedures and maintains required documentation on laboratory and specimen conditions. Ensures laboratory conditions and equipment are properly cleaned and maintained in accordance with established procedures. Assists with general lab maintenance and cleaning. Assists with the technical aspects of studies and experiments, including documentation and preparation of materials. Performs other duties as assigned. Working Conditions This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals. Required Qualifications Education: Bachelor’s degree or combination of education and experience may substitute for minimum education. No specific work experience required. Skills: communication, detailed reports, GraphPad, laboratory instrumentation, laboratory research, Microsoft Excel, organizing, records management, software program, troubleshooting, working independently. Driver’s license not required. Preferred Qualifications Previous work with Drosophila strongly preferred. Experience and working knowledge of diverse imaging strategies (confocal imaging). The ideal candidate will have up to one year of experience in a laboratory setting. Salary Range $16.92 - $26.44 hourly Grade

R06-H

Benefits Up to 22 days of vacation, 10 recognized holidays, and sick time. Competitive health insurance packages with priority appointments and lower copays/coinsurance. Free Metro transit U‑Pass for eligible employees. Defined contribution retirement savings plan, starting at 7% employee match. Wellness challenges, annual health screenings, mental health resources, mindfulness programs, employee assistance program, financial resources, access to dietitians. 4 weeks of caregiver leave; family care resources; tuition cover up to 100% at WashU and 40% elsewhere after seven years. EEO Statement Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information. #J-18808-Ljbffr Washington University in St. Louis