Manager, R&D Business Operations

Manager, Business Operations (Purchase Order Management)At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.What You Will Do:Create, generate, and manage purchase orders in Ariba/SAP following full contract execution, ensuring alignment with contract terms, budgets, and approved scopes of work in compliance with company policies and service level standard turnaround times.Translate contractual payment terms, milestones, and fee structures into accurate and compliant purchase order structures.Review executed agreements to ensure proper financial setup, including funding allocations, payment schedules, and budget tracking.Process and manage change orders, PO amendments, closures, and funding adjustments in accordance with contract modifications.Partner with R&D, Finance, and Strategic Sourcing to ensure timely PO issuance and resolution of system or budget discrepancies.Monitor purchase order lifecycle activities, including invoice matching, goods receipt confirmations, accrual support, and PO reconciliation.Ensure compliance with internal financial controls, delegation of authority policies, and procurement procedures prior to PO release.Serve as system subject matter expert (SME) for Ariba/SAP purchase order workflows and provide guidance to internal stakeholders.Train business partners on purchase requisition and PO processes, including proper documentation and system requirements.Facilitate weekly or monthly operational status meetings related to PO issuance, budget tracking, and financial metrics as appropriate.Generate reports and dashboards to track PO cycle times, open commitments, spend against budget, and operational KPIs.Support month-end and year-end close activities, including accrual validation and financial reconciliation.Identify and implement process improvements to enhance PO accuracy, system efficiency, and compliance with internal policies and external regulations.Support audit requests and compliance reviews related to procurement and purchase order activities.Your Profile:Bachelor’s degree required; advanced degree preferred.Minimum 5 years of experience in pharmaceutical/biotech business operations, procurement operations, finance operations, or contract-to-PO management.Demonstrated experience creating and managing purchase orders within enterprise systems (e.g., SAP, Ariba).Strong understanding of procure-to-pay (P2P) processes, including requisitioning, PO generation, invoice matching, and accruals.Experience working cross-functionally with R&D, Finance, Strategic Sourcing, Legal, and Accounts Payable.Strong analytical skills with the ability to interpret contract financial terms and translate them into operational system requirements.Working knowledge of pharmaceutical/biotech regulatory and compliance considerations impacting vendor payments and financial controls.Ability to identify financial discrepancies or operational risks and escalate appropriately.Strong organizational skills with the ability to manage multiple purchase orders, vendors, and deadlines simultaneously.Proficiency in Microsoft Office applications (Word, Excel, PowerPoint), with strong Excel skills for financial tracking and reporting.Experience supporting internal or external audits related to procurement or financial operations.Strong attention to detail and ability to interpret and apply company financial policies, procedures, and internal controls.Employment with ICON is contingent upon having the legal right to work in the country where the role is based.Rewards & BenefitsICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.Benefits may include:Competitive base salary and performance related incentivesHealth and wellbeing programmes including medical, dental, and vision coverage where applicableRetirement and pension plansLife assurance and disability coverageEmployee assistance programmes and wellbeing resourcesLearning and development opportunities through structured training and career pathwaysBenefits may vary depending on role and location.Visit our careers site to read more about the benefits ICON offers.Inclusion and AccessibilityICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.Are you a current ICON Employee? Please click here to applySummaryLocation: US, Blue Bell (PRA); US, Cary, NC; US, Raleigh, NCType: Full time