LCMS Scientist
Eurofins USA Discovery Services
Job Description LCMS Scientist Responsibilities & Duties Include but are not Limited to the Following: Performs work in a laboratory setting, meeting the physical job requirements of a lab role. Conducts production assays primarily in ADME Toxicology Services, but may support BioMAP®, Immunosignaling, Ion Channel, and/or OncoPanel™ Services based on business needs. Develops Liquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/ DMPK applications Develops analytical methods supporting project teams both internally and externally for new assay development. Performs Troubleshooting and Maintenance of Mass Spectrometers and HPLC units. Experience with Sciex® or Waters Instrumentation is a plus. Prepares and manages inventory of buffers, reagents, semi-finished and finished goods. Provides solutions to more complex problems, identifies and initiates process improvements Maintains high data quality and reproducibility. Performs data and report QC review within the department, and may support study director. Takes ownership of client projects with minimal supervision. Supports validation of new methods, and contributes to expansion of service/product line, equipment, and data management systems. Understands and complies with requirements for work performed at a GxP site. Completes required training and supports 100% of Employee Health and Safety requirements. Demonstrates proficiency with, care and maintenance of lab equipment and department assets. Conducts responsible use of confidential IT and business systems, as required. Adheres to department SOPs and documentation requirements, maintains accurate data management and reporting. Supports unit goals and demonstrates Eurofins’ competencies, as defined in the job plan. Provides training to colleagues and external end users, when required. Contributes to scientific community, and site research and development objectives. Works effectively in a team environment, under minimum direction, to achieve business production, project timelines, and quality objectives. Adjusts work hours and provides cross-functional support to other departments, as required, and maintains accountability in delivering to client needs/timelines. Routinely communicates project updates to internal and external clients. Performs other duties, as assigned/ Qualifications B.S. with minimum 5 years relevant laboratory experience M.S. with minimum 3 years relevant laboratory experience Ph.D. with minimum 1 year relevant laboratory experience Or an equivalent of education and laboratory experience Basic Minimum Work Requirements: Direct experience with Liquid Chromatography- Mass Spectrometry and/or ultraviolet spectrometry (LC-MS or LC-UV) in a contract research organization or industry laboratory for ADME/ DMPK applications Experience working in a Quality Management System Scientific expertise with mass spectrometry-based quantification for ADME/ DMPK applications in biological matrices. Experience with analytical method development and optimization Familiarity with concepts of validation of bioanalytical methods in accordance with regulatory (FDA, ICH) guidelines Experience with liquid handling, automation, solid-phase extraction (SPE), HTS applications, and large-scale screening Experience in small team leadership and project management Experience in leading and delivering results in R&D or innovation programs Authorization to work in the United States indefinitely without restriction or sponsorship. The Ideal Candidate Possesses the Following: Good communication and interpersonal skills Demonstrated proficiency in contributing independently on a project team with time and quality deliverables Ability to read, write, and interpret documents, such as standard operating procedures and technical reports Ability to perform mathematical calculations, statistical analyses, and data interpretation Ability to multitask with organization and manage time effectively Ability to solve practical problems and troubleshooting skills Ability to work in a laboratory setting, according to physical requirements of a laboratory role Lab equipment and office computer/software proficiency Above average oral and written communication skills Demonstrates a positive attitude, capacity for team environment, and exhibits a genuine interest in drug discovery in support of advancing human health Ability to develop new methods, and lead research and development projects Ability to review and QC release data/reports Ability to lead small, informal sub-teams, train, and train new team members Ability to conduct mid-size projects with minimal supervision Ability to contribute to strategic vision, establishment of new service lines, equipment, and data management systems Ability to easily support cross-functional demands Additional Information Position is full-time working Sunday - Thursday or Saturday - Wednesday 8:00pm - 5:00 PM . Candidates currently living within a commutable distance of St. Charles, MO are encouraged to apply. Excellent full-time benefits including comprehensive medical coverage, dental, and vision options Life and disability insurance 401(k) with company match Paid vacation and holidays
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