Senior Manager-Environmental, Health, & Safety - Phoenix, AZ

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives. We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting‑edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do. But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose. Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary

Based in Phoenix, Arizona, the Senior Manager, Environmental, Health & Safety (EHS) provides operational leadership for EHS programs across the Phoenix sites. This role is responsible for the development, implementation, and sustainment of comprehensive systems that ensure compliance with all applicable federal, state, and local environmental, health, and safety regulations, as well as corporate EHS directives, policies, standards, and best practices. The position leads the development, maintenance, and continuous improvement of EHS procedures, programs, permits, plans, registrations, and company‑wide initiatives that support a safe and compliant workplace. Serving as the subject matter expert for EHS matters, the Senior Manager provides guidance and support to all personnel, departments, and site leadership to ensure adherence to regulatory requirements and operational excellence. The role develops and leads a team of EHS professionals and oversees the creation and management of EHS policies and procedures, conducts compliance audits and assessments, responds to emergencies, and leads investigations of workplace incidents, injuries, illnesses, and safety concerns. Working closely with company leadership, the Senior Manager drives proactive risk reduction efforts and fosters a culture of safety with the goal of eliminating injuries and losses.

Job Responsibilities

Provide operational leadership for Environmental, Health & Safety (EHS) programs across all Phoenix sites, ensuring alignment with corporate objectives, regulatory requirements, and industry best practices. Lead the development, implementation, standardization, and continuous improvement of EHS management systems, policies, procedures, standards, and programs that drive regulatory compliance, employee safety, environmental stewardship, and operational excellence across all sites. Ensure compliance with all applicable federal, state, and local EHS regulations, permits, registrations, licenses, and corporate requirements, while maintaining compatibility with quality standards. Serve as the primary EHS subject matter expert and trusted advisor to site leadership, functional leaders, and employees, providing strategic guidance on risk management, regulatory interpretation, incident prevention, and business initiatives. Lead, coach, and develop a team of EHS professionals supporting Phoenix operations, establishing consistent expectations, priorities, and program execution across all facilities. Drive a proactive safety culture through leadership engagement, employee participation, accountability programs, and continuous improvement efforts focused on eliminating injuries, illnesses, environmental incidents, and property losses. Oversee environmental compliance programs, including air quality, hazardous waste, wastewater, stormwater, chemical management, and other regulated activities; ensure all required permits, plans, registrations, and regulatory reports are maintained accurately and submitted on time. Partner with other functions to integrate EHS requirements into facility design, process improvements, capital projects, new equipment installations, and operational changes. Establish and maintain effective relationships with regulatory agencies, emergency response organizations, insurance representatives, community stakeholders, and external auditors, serving as the primary point of contact during inspections, audits, and compliance reviews. Provide oversight of incident management processes, including investigations of injuries, illnesses, environmental events, near misses, property damage, and regulatory non‑conformances; ensure root cause analyses and corrective actions effectively mitigate future risk. Direct emergency preparedness and incident response programs, including Emergency Response Team activities, emergency planning, drills, and coordination with local emergency services. Develop, implement, and oversee comprehensive EHS training strategies to ensure employee competency, regulatory compliance, leadership engagement, and workforce awareness across all Phoenix locations. Monitor emerging regulations, industry trends, and corporate requirements; proactively assess business impacts and implement necessary enhancements to maintain compliance and operational readiness. Lead continuous improvement initiatives that reduce organizational risk, improve compliance, strengthen environmental sustainability, and enhance employee health, safety, and well‑being. Collaborate with Corporate EHS leadership to deploy enterprise‑wide initiatives, share best practices, ensure program consistency, and support broader organizational EHS objectives. Perform additional leadership responsibilities and enterprise EHS initiatives as assigned.

Required Qualifications

• Bachelor's degree in Environmental Science, Environmental Engineering, Occupational Health & Safety, Industrial Hygiene, Safety Management, Chemical Engineering, Public Health, Biology, Chemistry, Engineering, or a related scientific or technical discipline.
• Minimum of 7 years of progressive EHS in a regulated, pharmaceutical, biotechnology, medical device, life sciences, or healthcare complex environment.
• Minimum of 5 years of EHS leadership experience managing EHS professionals, programs, or multi‑site operations.
• Demonstrated experience developing, implementing, and leading enterprise or multi‑site EHS management systems and compliance programs.
• Expert knowledge of federal, state, and local environmental, health, and safety regulations, including OSHA, EPA, DOT, RCRA, hazardous waste, air quality, stormwater, wastewater, industrial hygiene, chemical safety, and emergency preparedness requirements.
• Experience managing environmental compliance programs, permits, regulatory reporting, inspections, and agency interactions.
• Advanced expertise in risk assessment, hazard identification, incident investigation, root cause analysis, corrective action management, and continuous improvement methodologies.
• Strong understanding of regulated manufacturing environments and the integration of EHS requirements with quality and GMP/CAP/CLIA standards.
• Demonstrated ability to develop, implement, and sustain EHS strategies, management systems, policies, standards, and governance programs across multiple facilities.
• Proven ability to lead regulatory inspections, audits, compliance reviews, and agency interactions.
• Ability to analyze EHS performance metrics, identify trends, establish key performance indicators (KPIs), and develop data‑driven improvement strategies.
• Demonstrated capability to influence and partner effectively with leaders at all organizational levels.
• Excellent verbal, written, presentation, and executive communication skills.
• Ability to manage multiple priorities while leading cross‑functional initiatives in a dynamic business environment.

Preferred Qualifications

• Master's degree in Environmental Health & Safety, Environmental Engineering, Industrial Hygiene, Public Health, Engineering, Business Administration (MBA), or a related discipline.
• Professional certifications such as CSP, CIH, CHMM, etc. RCRA, DOT, HAZMAT, Incident Command System (ICS), Emergency Management, or related certifications.
• Experience leading EHS functions across multiple sites.
• Experience building EHS organizations, leading cultural transformation initiatives, and driving enterprise‑wide safety performance improvements.
• Experience supporting facility expansions, capital projects, equipment qualifications, process changes, startups, or site integrations.
• Experience implementing ISO 14001 and/or ISO 45001 management systems.
• Experience with sustainability, environmental stewardship, waste reduction, energy management, or corporate ESG initiatives.
• Experience utilizing EHS software platforms, business intelligence tools, and advanced analytics to drive compliance and performance improvements.

Physical Demands

Will work at a computer, perform walking inspections and tours of building interiors and exteriors. Able to perform essential job functions including walking, standing, climbing stairs, and moving throughout office and industrial environments without restriction. Capable of lifting 30 lbs.

Training

Bloodborne Pathogens Exposure Control, Chemical Hygiene, Hazard Communications, Hazardous Waste Management, and OSHA Injury & Illness Reporting Requirements. First Aid & CPR Other job specific and compliance training assigned based on the job functions associated with this position.

Other

This position requires periodic travel and some evenings, weekends and/or Holidays. Job may require after‑hours response to emergency issues.

Conditions of Employment

Individual must successfully complete pre‑employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification. This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

Caris Life Sciences is a leading innovator in molecular science and artificial intelligence focused on fulfilling the promise of precision medicine through quality and innovation. Caris is committed to quality and excellence at our state‑of‑the‑art laboratories. Learn more about our tissue lab and the advanced technologies that are helping improve the lives of cancer patients.