Postdoctoral Research Scholar - PHHI

Job Posting Posting Number: PG191722PD Position Number: 00109897 Position Type: Post Doc FLSA: Exempt Department ID: 110308 - Kannapolis Research Department: 110308 - Kannapolis Research Location: Kannapolis, NC Position Overview The Postdoctoral Scholar will assist the Principal Investigator (Dr. Andrew Neilson) in the Plants for Human Health Institute by leading and conducting independent research (80%), along with some general laboratory management (10%), and some mentoring of graduate students as appropriate (10%). Duties and Responsibilities The primary duties of this position will include conducting advanced independent and/or directed research with a focus on the interaction between plant–derived phytochemicals, the human gut microbiome and nutrition/health outcomes. Major research thrusts in the Neilson lab currently involve 1) utilizing phytochemicals to modulate production of gut microbiome–derived uremic toxins such as trimethylamine N‑oxide (TMAO), phenylacetic acid, phenylacetylglutamine, and imidazole propionate, and 2) understanding individual genetic differences that predict phytochemical bioavailability, metabolism, and efficacy for disease prevention, among others. The majority of the work will be performed using four key research tools: 1) anaerobic fecal fermentations, 2) rodent models of nutrition/disease (including models of genetic variety), 3) mammalian and/or bacterial cell culture, and 4) instrumental analysis (particularly LC–MS/MS). This will include study design, collection and analysis of data, ensuring quality of data, basic statistics analysis, generating tables and figures for presentation (in manuscripts and conference presentations) as it relates to impacts on human health, participation in preparation and submission of manuscripts, reports and grant proposals. Other general duties will include general lab and instrument maintenance and management as well as other duties as assigned. In addition to performing assigned experiments, the successful candidate will contribute to the intellectual direction of the lab by identifying important research questions, formulating hypotheses and designing experiments (including adoption of new techniques) to test those hypotheses. The candidate must have a demonstrated ability to work independently and creatively. She/He will provide support to peers, collaborative partners, and students, have good communication skills, and be able to articulate clearly the scientific and technical needs in the field, set clear goals, and work within an interdisciplinary setting. The successful candidate will be expected to develop and submit (with guidance from the Principal Investigator) postdoctoral fellowship applications and other grant applications to sponsors such as USDA, NIH, etc. The successful candidate is expected to routinely publish their research in relevant peer‑reviewed academic journals. Work Schedule Mon‑Fri, approx 8 am‑5 pm; work may sometimes be required outside of these hours due to the inherent nature of animal and bacterial experiments required for this position. Requirements Doctoral Degree in Microbiology, Molecular Biology, Nutrition Science, Food Science, Chemistry, Biochemistry, Toxicology, or a related field. Experience in one or more of the following fields: anaerobic microbiology/fermentations, molecular biology (PCR), analytical chemistry (particularly LC–MS/MS), in vitro work, or rodent work (gavage, injection, blood collection, etc.). Demonstrated record of publishing primary research findings in peer‑reviewed scientific journals. Strong written and oral English communication skills. Ability to lead complex research projects with knowledge of advanced microbiological, molecular, and/or analytical chemistry techniques as appropriate for plant‑derived phytochemicals. Ability to train and supervise graduate students and visiting scholars. Responsible for data acquisition, statistical processing, and interpretation as well as development and maintenance of datasets, and use of basic statistical and other software packages. Preferred Qualifications Experience in one or more of the following areas: anaerobic microbiology or fermentation; molecular biology; rodent research methods; gnotobiotic/germ‑free animal research; biology and physiology of diabetes/obesity/cardiovascular disease; genetics/GWAS/QTL; polyphenol chemistry; ELISAs/RIAs; xenobiotic bioavailability/pharmacokinetics and metabolism; mammalian cell culture; fractionation or preparative chromatography; enzymology; molecular biology; in vitro fecal fermentations; in vitro digestions or dissolution testing; toxicology. Preference will be given to candidates with expertise in microbiology, gut microbiome, and molecular biology. Benefits Medical, Dental, Vision, Retirement and Leave Faculty and Staff Assistance Program Enhance your career with LEAD courses Attend non‑revenue generating sporting events for free. Driver’s License Valid NC Driver's License required: Yes. Equal Opportunity Statement NC State University is an equal opportunity employer. All qualified applicants will receive equal opportunities for employment without regard to age, color, disability, gender identity, genetic information, national origin, race, religion, sex (including pregnancy), sexual orientation, and veteran status. The University encourages all qualified applicants, including protected veterans and individuals with disabilities, to apply. Individuals with disabilities requiring disability‑related accommodations in the application and interview process are welcome to contact View phone number on click.appcast.io to speak with a representative of the Office of Equal Opportunity. NC State University participates in E‑Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States. #J-18808-Ljbffr