Medical Director, Clinical Science - Thoracic Oncologyence

Medical Director, Clinical Science – Thoracic Oncology Role & Responsibilities Provide medical and scientific leadership for design, execution, and interpretation of global clinical studies in thoracic oncology (NSCLC, SCLC, and other intrathoracic malignancies). Partner with Clinical Development to translate program strategy into high-quality protocols, robust data, and regulatory-grade deliverables (first-in-human through registrational and lifecycle expansion). Contribute to clinical development plan/strategy, dose selection/optimization, biomarker and patient-selection strategies (e.g., histology, PD-L1), and study design implications. Author/co-author protocols, amendments, informed consent templates, investigator brochures, and clinical study reports. Serve as medical monitor/deputy medical monitor (eligibility adjudication, deviation review, dose-modification guidance, site medical support). Partner with Clinical Operations/CROs on feasibility, site selection, enrollment strategy, and risk mitigation; support ongoing safety/efficacy review and data review/interpretation. Prepare/support committee materials (IDMC, Dose Escalation, Safety Management); partner with Pharmacovigilance on safety review and benefit-risk. Support IND/CTA content, briefing books, health authority responses, marketing applications, and health authority interactions. Required Qualifications MD/PhD, MD, or DO (or international equivalent) with completed residency; board eligibility/certification in Medical Oncology, Hematology/Oncology, or Internal Medicine; 5+ years clinical research experience (industry/CRO/academia strongly preferred). Direct oncology clinical trial experience with protocol development and study conduct exposure. Working knowledge of ICH-GCP, oncology regulatory requirements, and global clinical trial environment. Familiarity with RECIST 1.1, CTCAE, and endpoints (ORR, PFS, OS, DoR). Strong written/verbal scientific communication; global matrix effectiveness. Preferred Qualifications Thoracic malignancy focus (NSCLC/SCLC); immuno-oncology/antibody modality experience (irAE management); health authority interaction and registrational design exposure; alliance/partnered program experience; peer-reviewed publications. Travel Willingness to travel internationally to investigator meetings, congresses, partner sites, and Takeda locations. #J-18808-Ljbffr Scorpion Therapeutics