Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Scientist/Team Leader - Bioprocess Development

$107.6k - $161.5k

Ecolab

About The Role We are seeking a passionate and experienced Senior Scientist/Team Leader – Bioprocess Development to lead downstream process development team focused on the chromatographic purification of monoclonal antibodies (mAbs). This role is central to our mission of enabling large and small biopharmaceutical companies to bring transformative therapies to patients faster and more efficiently. As a scientific leader, you will guide a team in designing and executing purification strategies that support late-stage development and manufacturing readiness. You’ll work closely with external biopharma clients, helping them advance their molecules toward commercialization—ultimately impacting patient lives around the world. Key Responsibilities Lead a team of bioprocess development scientists and serve as a subject matter expert in monoclonal antibody downstream processing with a heavy focus on preparative chromatography. Partner with leaders across Ecolab’s global Bioprocessing labs to address complex purification challenges. Design, execute, and analyze chromatography-based purification processes for mAbs, including Protein A, ion exchange, HIC, and related modalities. Develop scalable, robust purification processes tailored to client molecules and manufacturing objectives. Lead technology transfer activities with external manufacturing partners. Prepare technical reports, protocols, and documentation to support regulatory submissions. Work directly with leading biopharma clients to align on study design, timelines, and deliverables. Deliver high-quality experimental data that supports client development programs and regulatory filings. Act as a trusted scientific partner, helping clients resolve technical challenges and accelerate progress toward commercialization. Manage daily lab operations, including equipment maintenance, inventory, and safety compliance. Mentor junior scientists and research associates, supporting their technical growth and execution excellence. Promote a culture of scientific rigor, operational discipline, and continuous improvement. Minimum Qualifications M.S. in Biochemistry, Chemical Engineering, Biotechnology, or related field with 8+ years of relevant industry experience, or Ph.D. with 4+ years of experience in downstream process development for biologics. Demonstrated expertise in preparative chromatography and antibody purification. Proven ability to lead small scientific teams and manage lab operations. Preferred Qualifications Hands-on experience with AKTA systems, Unicorn software, and high-throughput screening platforms (e.g., Tecan Te-Chrom). Proficiency in analytical techniques such as HPLC, SDS-PAGE, ELISA, UV spectroscopy. Familiarity with tech transfer, cGMP/cGLP standards, and regulatory documentation. Experience in client-facing or CDMO environments is a plus. Strong communication, organizational, and problem-solving skills. Working knowledge of statistical tools (e.g., JMP,) and data analysis software Why This Role Matters This is more than a lab-based leadership role—it’s an opportunity to directly influence the development of biologic therapies that improve and save lives. You’ll be working with some of the world’s leading biopharma companies, helping them refine and scale their purification processes to bring innovative treatments to patients in need. Annual Or Hourly Compensation Range The base salary range for this position is $107,600.00 - $161,500.00. This position is eligible for annual bonus pay based on performance, per plan terms. Many factors are taken into consideration when determining compensation, such as experience, education, training, geography, etc. We comply with all minimum wage and overtime laws. Benefits Ecolab strives to provide comprehensive and market-competitive benefits to meet the needs of our associates and their families. Click here to see our benefits. If you are viewing this posting on a site other than our Ecolab Career website, view our benefits at jobs.ecolab.com/working-here. Potential Customer Requirements Notice To meet customer requirements and comply with local or state regulations, applicants for certain customer-façing roles may need to: Undergo additional background screens and/or drug/alcohol testing for customer credentialing. Americans With Disabilities Act (ADA) Ecolab will provide reasonable accommodation (such as a qualified sign language interpreter or other personal assistance) with our application process upon request as required to comply with applicable laws. If you have a disability and require accommodation assistance in this application process, please visit the Recruiting Support link in the footer of each page of our career website. Our Commitment to a Culture of Inclusion & Belonging At Ecolab, we believe the best teams are inclusive. We are on a journey to create a workplace where every associate can grow and achieve their best. We are committed to fair and equal treatment of associates and applicants and recruit, hire, promote, transfer and provide opportunities for advancement based on individual qualifications and job performance. In all matters affecting employment, compensation, benefits, working conditions, and opportunities for advancement, we will not discriminate against any associate or applicant for employment because of race, religion, color, creed, national origin, citizenship status, sex, sexual orientation, gender identity and expressions, genetic information, marital status, age, disability, or status as a covered veteran. In addition, we are committed to furthering the principles of Equal Employment Opportunity (EEO) through affirmative action (AA). We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance, the San Francisco Fair Chance Ordinance, and the New York City Fair Chance Act. #J-18808-Ljbffr Ecolab

Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Senior Scientist/Team Leader - Bioprocess Development in King of Prussia, PA vacancy
  • A bioprocessing client is seeking a Senior Scientist in King of Prussia, PA. This role is fully on site and entails leading downstream process development, specifically chromatographic purification of monoclonal...  ...ability to manage a small team. Key responsibilities include... 
    Senior

    Insight Global

    King of Prussia, PA
    3 days ago
  • $135k

    Senior Scientist - Downstream Process Development Job Description One of our large bioprocessing clients is seeking a Senior Scientist to join their R&D team in King of Prussia, PA. This role is fully on site, 5 days/week and will lead downstream process development efforts... 
    Senior
    Full time

    Insight Global

    King of Prussia, PA
    3 days ago
  •  ...searching for the best talent for a Senior Scientist - Lentiviral Vector Upstream Process Development to be based in Spring House, PA...  ...in cross-functional team environments. Previous experience...  ...with technology transfer of a bioprocess to clinical or commercial GMP manufacturing... 
    Senior
    Full time
    Local area
    Weekend work

    Johnson & Johnson

    Spring House, PA
    3 days ago
  • $117k - $184.2k

     ...global biopharmaceutical leader with a portfolio of prescription...  ...investors in Research & Development.We are seeking a motivated Senior Scientist to join our Digital Insights team within the Development...  ...Analytical Chemistry, Biology, Bioprocessing, Business Development,... 
    Senior
    Full time
    For contractors
    Local area
    Flexible hours

    Merck Sharp & Dohme (MSD)

    West Point, PA
    3 days ago
  • $135k

    A leading bioprocessing firm is seeking a Senior Scientist in King of Prussia, PA to lead downstream process development for monoclonal antibodies. The role requires strong expertise in chromatography...  ...and the ability to manage a small team. Ideal candidates will have a M.S. or... 
    Suggested

    Insight Global

    King of Prussia, PA
    3 days ago
  • A global biopharma company is seeking a Senior Scientist in King of Prussia to lead the Upstream manufacture of clinical supplies for investigational biopharmaceutical molecules. This role requires expertise in Good Manufacturing Practices (GMP) and hands-on experience... 
    Senior

    GSK

    King of Prussia, PA
    3 days ago
  • Ecolab in King of Prussia, PA is seeking a Senior Product Manager to drive sales and marketing initiatives within the Bioprocessing business, leading commercial strategies that...  ...collateral, and drive cross-functional teams to translate customer needs into growth across... 
    Senior
    Remote job

    Ecolab

    King of Prussia, PA
    2 days ago
  • $260k - $318k

     ...premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the...  ...talent, at the right time, in the right way.The Senior Director, Clinical Scientist, will support the development and execution of clinical trials for assets targeting... 
    Senior
    Minimum wage
    Full time
    Local area
    Flexible hours

    Madrigal Pharmaceuticals

    Conshohocken, PA
    5 days ago
  • Ecolab is seeking a Senior Scientist/Team Leader - Bioprocess Development to lead a downstream purification team focused on monoclonal antibodies. You will guide purification strategies, design scalable processes, and partner with biopharma clients to advance molecules... 
    Senior

    Ecolab

    King of Prussia, PA
    3 days ago
  •  ...for the best talent for our Senior Principal Scientist, Bioanalysis to be located...  ...Visionaries like you work on teams that save lives by...  ...Bioanalytical Discovery and Development Sciences (BDDS) organization...  ...a scientific and technical leader in both ligand-binding assays... 
    Senior
    Full time
    Local area

    Johnson & Johnson

    Spring House, PA
    3 days ago
  • $33.6 per hour

    Kelly is seeking a Scientist 1 - Research and Development in Spring House, PA, to work in collaboration with Johnson & Johnson. This position focuses on bioprocessing and automation in life sciences, providing a great opportunity to grow your career while making a meaningful... 
    Hourly pay

    Kelly

    Spring House, PA
    3 days ago
  •  ...Services in Spring House, PA is seeking a Scientist 1 - Research and Development to support bioprocessing work with Johnson & Johnson. The...  ...new sensor technologies, and report findings to senior staff while collaborating across teams. #J-18808-Ljbffr Kelly Services
    Hourly pay
    Weekend work
    Weekday work

    Kelly Services

    Spring House, PA
    4 days ago
  • Senior Scientist-BiologicsTitle: Senior Scientist, Biologics Location: Exton,PA Full-timeFrontage Laboratories Inc. Frontage Laboratories...  ...broad expertise in supporting pre-clinical and clinical drug development. Frontage operates out of several different locations within... 
    Senior
    Contract work

    Frontage Laboratories

    Exton, PA
    5 days ago
  • Senior Method development scientist-Biomarker LC-MS/MSTitle: Senior method development scientist- Biomarker LC-MS/MSLocation: 700 Pennsylvania Dr. Exton...  ...scientist will be a member of the method development team, the responsibility includes serving as subject matter expert... 
    Senior
    Contract work

    Frontage Laboratories

    Exton, PA
    3 days ago
  •  ...are searching for the best talent for a Senior Scientist, In-vivo CAR-T, to be based on-site in...  ...:The Senior Scientist will support the development, optimization, and scale-up of lentiviral...  ...Quality, Manufacturing, and Regulatory teams to ensure alignment on process strategy... 
    Senior
    Full time
    Local area

    Johnson & Johnson

    Spring House, PA
    3 days ago
  • $117k - $184.2k

     ...statistical programming activities for late stage drug/vaccine clinical development projects. This may include leadership of one or more projects....  ...forecasting.Coordinate the activities of a global programming team that includes outsource provider staff.Support NDA/BLA... 
    Senior
    Full time
    Part time
    For contractors
    Local area
    Remote work
    Visa sponsorship
    Flexible hours

    Merck Sharp & Dohme (MSD)

    North Wales, PA
    6 days ago
  • GSK is seeking a QC Senior Scientist - Microbiology in King of Prussia, PA, to lead microbiology testing of drug products and raw materials, ensuring release and stability for production use. You will mentor analysts, review data, and support regulatory submissions and... 
    Senior
    Weekend work

    GSK

    King of Prussia, PA
    4 days ago
  • $117k - $184.2k

    Job DescriptionThe Senior Clinical Scientist provides scientific leadership for one or more clinical...  ...trials or key components of a clinical development program within the assigned...  ...Directors and cross-functional study teams to ensure study objectives, endpoints... 
    Senior
    Full time
    For contractors
    Second job
    Local area
    Flexible hours

    Merck Sharp & Dohme (MSD)

    North Wales, PA
    3 days ago
  •  ...Johnson Innovative Medicine is seeking a Senior Scientist, In-vivo CAR-T, based on-site in Spring House, PA. The role focuses on the development, optimization, and scale-up of LVV drug...  ...collaborate with modelling and data science teams, and contribute to technology transfer... 
    Senior

    Johnson & Johnson Innovative Medicine

    Spring House, PA
    15 hours ago
  •  ...Johnson in Spring House, PA is seeking a Senior Scientist, In-vivo CAR-T to advance LVV drug product processes from early to late development. The role combines hands-on lab work...  ...Development, MSAT, Quality, and Regulatory teams to ensure robust, GMP-ready processes. You... 
    Senior

    6084-Janssen Research & Development, LLC Legal Entity

    Spring House, PA
    15 hours ago
  • $133.7k - $200.6k

    As a Senior Product Manager, you will drive sales &...  ...initiatives within the Bioprocessing business, supporting...  ...and field applications teams to define market opportunities...  ..., business case development, and financial...  ...customers, key opinion leaders, channel partners, and... 
    Senior
    Hourly pay
    Minimum wage
    Remote work

    Ecolab

    King of Prussia, PA
    2 days ago
  •  ...Description Job Description Role: Scientist, Biomarkers This is a fully onsite...  ...healthier, cleaner and safer. We provide our teams with the resources needed to achieve...  ...science a step beyond through research, development and delivery of life-changing therapies.... 
    Senior
    Full time
    Work at office
    Relocation
    Relocation package
    Collegeville, PA
    more than 2 months ago
  •  ...Function Discovery & Pre-Clinical/Clinical Development Job Sub Function Biotherapeutics R&D...  ...searching for the best talent for a Senior Scientist, In-vivo CAR-T, to be based on-site in...  ...Quality, Manufacturing, and Regulatory teams to ensure alignment on process strategy... 
    Senior
    Local area

    Johnson & Johnson Innovative Medicine

    Spring House, PA
    15 hours ago
  •  ...Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biotherapeutics R&D...  ...searching for the best talent for a Senior Scientist, Cell Therapy Genetic Regulation to be...  ...and collaborate across cross-functional teams. This role is an exciting opportunity to... 
    Senior
    Local area

    6084-Janssen Research & Development, LLC Legal Entity

    Spring House, PA
    2 days ago
  •  ...and safer. We provide our teams with the resources needed to...  ...step beyond through research, development and delivery of life-...  ...research organization and world leader in serving science. We are...  ...Impactful Work The Senior Research Scientist independently performs, oversees... 
    Senior
    Full time
    Contract work
    Work at office
    Collegeville, PA
    15 days ago
  •  ...Senior Clinical Scientist - Infectious Disease (HIV) ICON plc is a world-leading healthcare intelligence...  ...to shape the future of clinical development. What you will be doing:   May...  ...Leads the Medical Monitoring (MM) team in performing MM activities, including... 
    Senior
    Remote work
    Work visa
    Flexible hours

    ICON Clinical Research

    Blue Bell, PA
    4 days ago
  •  ...Function \ Discovery & Pre-Clinical/Clinical Development \ Job Sub Function \ Biological...  ...advancements. Visionaries like you work on teams that save lives by developing the...  ...are searching for the best talent for a Senior Scientist, Multiomics Discovery located in Spring... 
    Senior
    Local area

    6084-Janssen Research & Development, LLC Legal Entity

    Spring House, PA
    3 days ago
  • $117k - $184.2k

     ...our company's renowned Research and Development division. Quantitative scientists, in partnership with other subject...  ...members of cross-functional safety teams (e.g., Safety Physicians and Scientists...  ...company is a global health care leader with a diversified portfolio of... 
    Senior
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    MSD Malaysia

    North Wales, PA
    15 hours ago
  • $117k - $184.2k

    Senior Scientist, Transporters Science Our company is a global health care leader with a diversified portfolio of prescription medicines,...  ...stages of drug discovery and development. The group also advances ADME...  ...data in support of project teams across therapeutic areas. This... 
    Senior
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    MSD UK

    West Point, PA
    3 days ago
  •  ...provide biostatistics consulting throughout all phases of drug development, ensuring compliance with regulatory requirements. The ideal...  ...considerable experience. The role involves close collaboration with senior management, mentoring junior staff, and presenting findings at... 
    Senior

    INC Research

    King of Prussia, PA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Scientist/Team Leader - Bioprocess Development. Be the first to apply!