Contract Senior Research Associate, Proteomics
Flare Therapeutics Inc.
In this role you will…
- Execute experiments to inform target engagement on transcription factors using a variety of approaches which include tissue cell culture, automated workflows and characterization using mass-spectrometry based proteomics
- Execute high-throughput global proteomics characterization of transcription factors using isotope labeling, TMT, alternative proteases, targeted proteomics (PRM or equivalent) label-free workflows
- Generate data in a timely manner; support lead discovery initiatives and regularly contribute at the bench
- Work closely with senior staff to set experimental strategy, project goals, and timelines to drive projects toward successful completion
- Work closely with biology, biochemistry, chemistry and compound management teams in early discovery to optimize screening on high-value transcription factors
- You have a B.S or M.S in chemoproteomics, chemical biology, biochemistry or analytical chemistry
- You have 1-3 years of experience in industry
- You have knowledge of proteomics principles and hands-on experience in mass spectrometry-based quantitative proteomics that includes DDA, DIA and/or LFQ
- You may have experience in targeted proteomics and TMT-based workflows,
- You may also have understanding of proteomics sample preparations using both 96- and 384-well plate formats using SP3
- You may have prior experience with assay development, sample prep automation, HPLC fractionation
- You have a desire to work in a lab-based role within a highly adaptive, fast-paced collaborative environment and can creatively solve problems through innovation and communication
- You have self-motivation, great decision making, organizational, analytical, interpersonal and communication skills
Vacancy posted 2 days ago
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