Senior Research Assistant

About Us: The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursueour missionat MSK and around the globe. Memorial Sloan Kettering Cancer Center seeks Senior Research Assistant in New York, NY to coordinate the laboratory biobank, including the reception and banking of specimens derived from clinical practice or from an array of clinical trials being held in MSKCC, as well as processing of the clinical specimens for downstream applications including the development of patient-derived xenograft (PDX) models, single cell RNA/ATAC/DNA/CITE sequencing, spatial transcriptomics and flow cytometry. Coordinate with a multidisciplinary team involving different MSKCC core facilities, clinicians and research coordinators, and development and maintenance of reference databases. Coordinate with the pathology core at MSKCC for the performance of histology work (including embedding, sectioning, immunohistochemistry and review of tissue, and state-of-the art multiplexed imaging techniques). Employ novel technologies in the lab, including single cell nuclei sequencing of small biopsies and PDXs and simultaneous single nuclei RNA/ATACseq and single nuclei DNAseq on flash frozen tissue samples. Provide in-vivo experiment support, including preparing cells for injection into mice, and processing collected specimens for preservation for downstream molecular analyses (RNAseq, ATACseq, ChIPseq and proteomics). Lead independent research projects related to lung cancer therapeutics. Supervise, mentor, and train new recruits in molecular biology and cell culture techniques. Assist postdocs and Ph.D. students with molecular biology work, including Western Blots, routine cell culture work, FACS sorting, flow cytometry, plasmid amplification, and PCR. Acting as the safety manager of the laboratory by coordinating with the institutional Environmental, Health and Safey and ensuring the lab is compliant with safety standards. EEO/VETS/ADA. REQUIREMENTS: Master’s degree or equivalent in Biology, Biochemistry, Biomedicine, or a directly related health science field and 3 years of experience in the job offered or working in medical research; or a Bachelor’s in these fields and 5 years of experience in the job offered or working in medical research. Must have 3 years of experience with the following: simultaneous single nuclei RNA/ATACseq and DNAseq on flash frozen tissue samples; and leading research projects in lung cancer therapeutics as evidenced by publications in the field. Must have 1 year of experience with the following: processing of clinical specimens and maintenance of the laboratory biobank; training of lab members in molecular and cell biology techniques; and writing and renewing IACUC and IBC protocols. SALARY: $77,100.00 - $119,400.00/year LOCATION: 417 East 68th St., New York, NY 10065 Pay Range: $77,100.00 - $119,400.00 FSLA Status: Exempt Closing : At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills. MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment. #J-18808-Ljbffr