Manager, Disease Strategy Finance
Vertex Pharmaceuticals
Job DescriptionThe Manager, Disease Strategy Finance is a key member of Vertex's Disease Strategy Finance Team, providing financial and strategic insights to inform Disease Strategy Teams (“DSTs”) on key decisions. This role will work closely with Directors on the DST Finance team to conduct financial modeling, forecasting, and scenario-based valuations. The Manager, Disease Strategy Finance will also play a critical role in creation of the Annual Budget, Long-Term Plan (LRP), and other financial forecasts in collaboration with colleagues. The role will partner closely with members of the global COFO organization, including finance teams supporting R&D, Biopharmaceutical Sciences and Manufacturing, Corporate, and Commercial. This role offers an opportunity to make a lasting impact by driving profitable growth while creating transformative medicines for people with serious diseases.Position Summary: Reporting to the Senior Director, Finance – Disease Strategy Teams, the Manager is a key member of Vertex’s Strategy Finance team and the global FP&A organization. This role will lead financial analysis required to inform Disease Strategy Teams (“DSTs”) on key decisions. Financial analyses will include financial modeling, forecasting, and scenario-based valuations. The Manager FP&A, Strategy Finance will also play a critical role in creating the Annual Budget, Long-Term Plan (LRP), and other financial forecasts. The role will be primary lead for preparation of collaboration financials for both internal and external partner reporting. The role will partner closely with members of the global CFO organization, including finance teams supporting R&D, Biopharmaceutical Sciences and Manufacturing, and Commercial. This role offers an opportunity to make a lasting impact by driving profitable growth while creating transformative medicines for people with serious diseases.Key Responsibilities:Prepare a wide range of financial analyses to inform DST decisions on investments.Lead preparation of alliance/collaboration financials for revenue/cost sharing in accordance with co-development/co-commercialization contract terms.Develop and maintain financial models covering all aspects of biopharmaceutical research, development, manufacturing, and commercialization.Provide Strategy Finance input into regular financial planning processes (Annual Budget, Forecasts, Long-Range Plan), for assigned Disease Areas.Manage Disease Area P&Ls for assigned DSTs, including ensuring consistent presentation of DST finances across Vertex, explanation of variances vs. forecasts, identification of risks/uncertainties, and opportunities for mitigation.Prepare a wide range of presentations for cross-functional stakeholders and senior leaders.Collaborate throughout CFO organization to identify and deliver on process improvement opportunities.Qualifications:B.S. Degree in Finance, Economics, or related quantitative/analytical field; MBA preferred.5+ years of relevant finance and industry experience - Biotechnology/Pharmaceutical industry experience strongly preferred.Experience with biopharma alliance/collaboration accounting preferred though not required.Understanding of biopharmaceutical drug research, development, manufacturing, and commercialization required.Exceptional analytical and financial skills to evaluate a broad range of financial questions – especially valuation, ROI/ROIC, and complex multi-disciplinary business decisions.Experience with Excel and PowerPoint; Experience with Hyperion (or another multidimensional database), business intelligence or visualization tools a plus.Proficient business acumen, judgment and knowledge of the company’s markets/products and industry trends.Strong communication skills, both written and verbal, and an eagerness to collaborate with colleagues (within or outside of finance) in sharing insights and learnings. Must be able to work well with senior leaders, peers, and junior team members.Possesses a high degree of attention to detail and ownership over work product with the flexibility to adapt to change.#HYBRID#LI-MF1Pay Range:$116,000 - $174,000Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.Flex Designation:Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select2. On-Site: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-HybridCompany InformationVertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at View email address on click.appcast.io: Boston, MAType: Full time
$160k - $190k
...desire to work on novel ideas. As a Senior Manager, FP&A, you will report to the Executive... ...financial reporting. You will support finance partnership with leaders in R&D, CMC, and... ...change the outcome of many human diseases. This belief is a pillar of our business...SuggestedTemporary workImmediate startFlexible hours$127k - $172k
...DescriptionManager, Enterprise Analytics and Strategy About Acrisure A global fintech leader,... ...of Enterprise FP&A & Reporting, the Manager of Enterprise Analytics & Strategy serves... ...a strategy consulting or strategic finance background, with the ability to independently...SuggestedFull timeWork at officeImmediate startFlexible hours$217k - $275k
...for chronic and progressive diseases—ensuring the right patient receives... ...Senior Director, Corporate Strategy and Operations will serve as... ..., with immediate focus on financing, out-licensing, and in-... ...development, executive operations, management consulting, or related...SuggestedImmediate start$125.5k - $230.2k
...pharmaceutical sectors Stakeholder management Collaborate with cross-... ...stakeholders, including Marketing, Finance, Market Access, MMD, HHI, and... ..., Vaccines, Immunology, Rare Diseases, or other pharmaceutical... ...assurance, consulting, tax, strategy and transactions. Fueled by sector...SuggestedTemporary workSummer holidayFlexible hours- Novartis Group of Companies in Cambridge, MA, seeks a senior leader to build and guide a disease modelling and quantitative pharmacology team. The role blends discovery through clinical development, with hybrid onsite presence averaging 12 days per month in Cambridge. The...Suggested
- ...and culture is amazing. Best place!!Job DescriptionJob Title: Finance & Enterprise Performance ConsultantJob Location: New York City,... ...accounting transaction processing analysis in finance areas You will be managing transitions of multiple processes from sending organization to...
$152.6k - $283.4k
...As the Associate Director, HCP Marketing Strategy, you will lead market shaping, branded... ...launch readiness initiatives that support disease awareness, diagnosis, referral pathways,... ...specialist referral and ongoing patient management.Contribute to KOL engagement strategy,...Full timeLocal areaRemote workRelocationShift work$152.6k - $283.4k
...the Associate Director, Patient Marketing Strategy, you will develop and execute patient-... ...focused marketing initiatives that support disease awareness, engagement, and launch... ...600.00 - $283,400.00Skills DesiredAsset Management, Commercial Excellence, Cross-Functional...Full timeLocal areaRemote workRelocationShift work$53k - $77k
...: Fellowship Program Coordinator Department : Infectious Diseases Location: Boston, MA Schedule : 40 hours per week, On-... ...including rotators from other institutions). Maintains a data management system ensuring timely and accurate data collection. Compiles...Full timeFixed term contractTraineeshipWork at officeFlexible hours$250k - $285k
...FXI (targeting thromboembolic diseases) and multiple programs... ...high-visibility role aligns finance with long range R&D operating... ...variances analysis. Prepare management analyses detailing budget-to... ...requirements and fundraising strategies. Partner with leadership team...Contract workWork at officeWork from homeFlexible hours$162k - $223k
...Associate Director, Medical Strategy & Operations (S&O) Lead is a... ...Affairs and a core member of Rare Disease LT. The role drives strategy-... ...audiences. Partner with Finance and medical Rare Disease LT to... ...governance processes, or program management required.Demonstrated...Temporary workLocal area- Boston Medical Center is seeking a Fellowship Program Coordinator to manage administrative activities for the Clinical Fellowship Education Program in Infectious Diseases. You will oversee onboarding, schedules, data collection, and compliance with ACGME and governing bodies...
- ...and reporting resultsLead testing, implementation, and change management for new capabilities including the automation of user, integration... ...and exceptional talent. Together, we power the future of finance - and this is what #LifeAtBNY is all about. Join us and be part...WorldwideFlexible hours
- Biogen seeks a Director of Rare Disease Market Access Strategy to lead the development and execution of the Market Access & Reimbursement (MA&R) strategy for SMA and ALS in the US. You will build payer messaging, pricing, contracting, and coordinate across MA&R functions...
- Emburse is seeking a Manager of FP&A (GTM) to own financial planning, forecasting, and analytics for Sales, Marketing, and GTM expenses. You will develop driver-based revenue and spend models, lead GTM reviews, and provide actionable insights to leadership. The role involves...Remote job
- Biogen, Inc. is seeking a Director of Strategic Pricing to lead the Rare Disease Market Access Strategy team in the US. You will develop and execute pricing and contracting strategies for SMA and ALS, aligning with the Rare Disease Franchise and reporting to the Head of...
- Galderma Pharma S.A is seeking a Senior Manager for U.S. FP&A in Boston. This role involves leading the preparation of monthly forecasts... ...timelines. Candidates should have a strong background in finance or accounting with 8+ years of experience in a corporate setting...
- Eight Sleep seeks a Strategic Finance Manager to own financial planning, forecasting, and reporting. You will partner with leadership to shape strategy and identify growth opportunities, owning dynamic financial modeling and ROI analyses. Location: SF. You will present...
- athenahealth is seeking a Senior FP&A Manager to lead forecasting, budgeting, and long-range planning across the organization. You will mentor a high-performing FP&A team, build financial models, and translate complex data into actionable insights for executive leadership...
$130k - $170k
Eight Sleep is seeking a Strategic Finance Manager in Boston (Hybrid). The role involves leading budgeting, forecasting, and financial modeling... ...other department leaders, contributing significantly to financial strategy and performance tracking. #J-18808-Ljbffr Eight Sleep$124k - $280k
...ApplicableSpecialismAdvisory - OtherManagement LevelSenior ManagerJob Description & SummaryThe OpportunityAs a Finance Function Strategy Consulting - Senior Manager, you will specialize in providing consulting services related to financial management and strategy. You will...Full timeH1b$132.3k - $245.7k
...Summary Job Title: Associate Director, Strategy, Oncology Disease Area #LI-Onsite Location: Cambridge,... ...experience in strategy, business, or finance within biopharma or related sectors Experience in management consulting, venture capital, or in-house biopharma...Relocation package- Join a leading financial services company as a Senior Program Manager, responsible for executing the Corporate Technology Strategy. You will lead key programs and manage cross-functional teams, ensuring alignment with organizational objectives. Ideal candidates have extensive...
$100k - $150k
...sleep, training, and overall health.WHOOP is hiring a Manager, Performance Marketing to help execute and optimize global... ...Brand Media, Marketing Analytics, Creative, Marketing Strategy & Operations, Product, and Finance to improve campaign performance and maximize the...Full timeWork at officeRelocation- ...Description: Title: Director, Vendor Performance Management Job Type: Full-time Location:... ...partners across operations, compliance, finance, and clinical teams and reports vendor... ..., finance, and clinical teams on vendor strategy and contracting. Requirements:...Full timeContract workWork at officeLocal areaRemote work
$170k - $215k
A leading construction firm in Boston is seeking a Senior Manager for Treasury to oversee daily cash operations and liquidity reporting. This role requires over 10 years of progressive corporate finance experience, a Bachelor's degree in finance or related field, and strong...- Job title: Head, Health System Strategy, Rare Diseases Location: Cambridge, MA 7 Products + 2 Launches $2.2B $3.1B (2030) 2 Direct Reports... ...the US Leadership Team and reports directly to the General Manager. Ready to get started? You'll be joining Sanofi's US Rare...
- Sanofi is seeking a Head, Health System Strategy, Rare Diseases in Cambridge, MA to lead provider-focused strategy across a $2.2B portfolio with... ...of the US Leadership Team, you will report to the General Manager, guide launch readiness across the portfolio, and #J-18808...
- Sanofi US in Cambridge, MA seeks a Head of Health System Strategy for Rare Diseases to lead provider-focused strategy across a multi-billion portfolio... ...and treatment access. The role reports to the General Manager and includes shaping cross-functional launch readiness....
- ...and shaping forecasting frameworks that finance teams actually use. At the Senior Consultant... ...PCMCS, ARCS, EDM) — including metadata management and data load processes Minimum 5 years... ...services, solutions and assets across Strategy & Consulting, Technology, Operations, Industry...Full timeWork experience placementLive inWork at officeLocal area
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Manager, Disease Strategy Finance. Be the first to apply!
- data strategy manager Boston, MA
- operations planning manager Boston, MA
- senior manager strategic initiatives Boston, MA
- sales excellence & strategy manager Boston, MA
- strategic account manager Boston, MA
- brand strategy manager Boston, MA
- commercial planning manager Boston, MA
- director strategic marketing Boston, MA
- workforce planning manager Boston, MA
- product strategy manager Boston, MA


