Associate Director, Engineering and Materials Science
$169.6k - $254.4kVertex Pharmaceuticals
Vertex Pharmaceuticals seeks an Associate Director in Engineering and Materials Science to lead cross-functional teams developing and scaling drug substance processes. The role combines technical oversight of small-molecule and oligonucleotide synthesis with strategic department contributions and mentorship of junior scientists.
Responsibilities
- Lead cross-functional engineering and science teams in developing multi-step syntheses for active pharmaceutical ingredient manufacture
- Direct drug substance process development from laboratory through technology transfer to manufacturing facilities
- Collaborate with materials, chemistry, analytics, and formulation groups to optimize drug substance properties across development phases
- Mentor junior scientists and contribute to departmental strategy as EMS leadership team member
- Champion process modeling adoption and potentially lead cross-functional strategic initiatives
Requirements
- BS in Chemical Engineering or related field with 11+ years pharmaceutical experience
- MS degree with 9+ years or PhD with 6+ years in Chemical Engineering or closely related discipline
- Expertise in small-molecule and oligonucleotide process development unit operations
- Demonstrated experience coaching and mentoring junior-level scientists
- Proficiency in process modeling, data analysis, and statistical design of experiments
- Strong stakeholder communication and cross-functional team leadership skills
- Ability to identify and resolve complex scale-up and process development challenges
Compensation: $169,600 - $254,400 base
$169.6k - $254.4k
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