Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Security Architect

Full-time

Johnson & Johnson

DePuy Synthes is recruiting for a Principal, Security Architect, located in the United States.

The Security Architect designs, evaluates, and strengthens the security architecture that protects DePuy Synthes technology assets, data, and operational environments. Sitting within the Technology Enterprise Strategy & Security organization, this role serves as a technical authority on security controls—assessing system and network configurations, identifying vulnerabilities and exposures, performing root-cause analysis, and contributing to the design, development, and implementation of countermeasures and security tooling across the enterprise.

This role is responsible for advancing the organization's Zero Trust, Secure by Design, and Resilient by Design strategy, ensuring security and resilience are embedded into every technology platform, architecture decision, and transformation initiative.

Key Responsibilities

  • Lead the development of Secure by Design, Resilient by Design, and Zero Trust architectures across cloud, network, endpoint, identity, application, data, and OT environments.
  • Conduct security architecture reviews, threat modeling, and risk assessments for new and existing solutions.
  • Drive the enterprise Zero Trust strategy, including identity, segmentation, least privilege, and continuous verification capabilities.
  • Design network segmentation and micro-segmentation architectures to protect critical assets and reduce lateral movement.
  • Define vulnerability and exposure management strategies, including risk-based prioritization and remediation.
  • Develop resilient security architectures that strengthen containment, recovery, and business continuity capabilities.
  • Design endpoint security controls, hardening standards, device compliance frameworks, and EDR/XDR integrations.
  • Establish secure architectures for cloud, AI, data, and application environments, including secure development, DevSecOps, and AI governance practices.
  • Develop OT security architectures that protect manufacturing, laboratory, and connected device environments.
  • Partner with Enterprise and Solution Architects to embed security, resilience, and compliance requirements across transformation initiatives.
  • Evaluate architectures and configurations against frameworks including NIST, NIST Zero Trust, CIS, ISO 27001, and applicable regulatory requirements.
  • Drive security automation, tooling integrations, and engineering improvements that enhance enterprise defenses.
  • Perform root-cause analysis of security findings and incidents, recommending strategic and sustainable improvements.
  • Produce architecture standards, reference designs, technical documentation, and executive-level roadmaps.
  • Mentor and coach security architects and engineers while fostering a culture of engineering excellence and continuous improvement.

Qualifications

Education:

  • Required: Bachelor's degree in Computer Science, Information Security, Engineering, or a related technical field.
  • Preferred: Master's degree in Cybersecurity, Information Security, or a related discipline.

Experience and Skills:

Required:

  • 8+ years of experience in information security, with demonstrated depth in security architecture and controls.
  • Hands-on experience with vulnerability and exposure management, including assessment and remediation.
  • Strong knowledge of network security and segmentation, firewalls, and zero-trust architecture.
  • Experience designing endpoint protection and device security controls (e.g., EDR/XDR, device hardening).
  • Experience with cloud security across one or more major platforms (AWS, Azure, or GCP), including secure configuration and workload protection.
  • Working knowledge of application and data security principles, including secure SDLC and data protection.
  • Familiarity with industry frameworks and standards (e.g., NIST CSF, ISO 27001, CIS Controls).

Preferred:

  • Experience securing Operational Technology (OT) and connected/IoT device environments.
  • Experience defining security controls for AI, data, and Generative AI solutions.
  • Experience in a regulated industry (MedTech, Pharmaceutical, or Healthcare) with familiarity in associated compliance requirements.
  • Experience with security automation, SOAR, and security tooling integration.
  • Experience supporting large-scale transformation or separation programs.

Other:

  • Travel: Up to 25%
  • Language: English proficiency required.
  • Certifications: Relevant security certifications (e.g., CISSP, CISSP-ISSAP, CCSP, SABSA, or cloud security certifications) preferred.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit .

Johnson & Johnson announced plans to separate our Orthopedics business to establish a standalone Orthopedics company, operating as DePuy Synthes. The process of the planned separation is anticipated to be completed within 18 to 24 months, subject to legal requirements, including consultation with works councils and other employee representative bodies, as may be required, regulatory approvals and other customary conditions and approvals. Should you accept this position, it is anticipated that, following conclusion of the transaction, you would be an employee of DePuy Synthes and your employment would be governed by DePuy Synthes employment processes, programs, policies, and benefit plans. In that case, details of any planned changes would be provided to you by DePuy Synthes at an appropriate time and subject to any necessary consultation processes.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via internal employees contact AskGS to be directed to your accommodation resource.

Vacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Principal Security Architect in New Brunswick, NJ vacancy
  •  ...DePuy Synthes is recruiting for a Principal, Security Architect, located in the United States. If you would like to know a bit more about this opportunity, or are considering applying, then please read the following job information. The Security Architect designs... 
    Principal
    Local area

    Johnson & Johnson

    New Brunswick, NJ
    8 days ago
  •  ...Johnson & Johnson's DePuy Synthes division seeks a Principal Security Architect to design and strengthen enterprise security architecture across cloud, network, endpoint, and operational technology environments. This technical leadership role advances Zero Trust and Secure... 
    Principal

    Johnson & Johnson

    New Brunswick, NJ
    17 days ago
  • $111k - $135k

     ...Position Type: Administration/ Assistant Principal Date Posted: 10/1/2026 Location: Highland Park High School, New Jersey Job Posting 2026-2027 School Year Position: Assistant Principal Location: Highland Park High School Dates Needed: January... 
    Principal

    Highland Park Public Schools

    Highland Park, NJ
    1 day ago
  • Job ID: 24656846Reference Number: 25-00091Title: Security ArchitectLocation: Iselin, NJ, 08830Posted Date: 2025-02-07Contact: Deepak KumarContact Email: ****@*****.*** Phone: (***) ***-****Company: HAN Staffing Requires overall understanding of Security services... 
    Suggested

    HAN Staffing

    Iselin, NJ
    4 days ago
  •  ...Role Databricks Architect Sr Data EngineerLocation Edison NJ Rmote Must Haves1 Candidate should have at 6 yrs of experience working on data workflow development in Azure stack with Databricks and ADF as Primary skill2 Strong understanding of Azure service components like... 
    Principal
    Work experience placement

    LTM

    New Brunswick, NJ
    6 days ago
  • $145k - $185k

    Job DescriptionWe are seeking a highly technical and forward-thinking security architect to help shape the future of enterprise security architecture, cloud security, and secure AI enablement across the organization. The Information Security Architect will help define... 
    Temporary work
    Work at office
    Remote work

    Bessemer Trust

    Woodbridge, NJ
    7 days ago
  • $150k - $350k

     ...Power of Withum Plus You - that’s the Power in the Plus!Job Description:We are seeking an experienced Cost Segregation Senior Manager/Principal to join our growing Forensic & Valuation Services Team. This role may be based in any of Withum's East Coast or West Coast offices... 
    Principal
    Full time
    Local area

    Withum Smith+Brown

    East Brunswick, NJ
    5 days ago
  • Job-ID31767297Reference26-00121 Responsibilities: Convert specifications into SAS code to generate datasets and Tables, Listings, and Figures outputs. Be responsible for overall project delivery, including clinical trial reports and other regulatory submission deliverables...
    Principal

    Katalyst Healthcares & Life Sciences

    New Brunswick, NJ
    3 days ago
  • MTS Solution Architect to design develop and implement scalable enterprise solutions that align with business objectives and technology...  ...transformation initiativesTranslate business requirements into scalable secure and highperformance technical solutionsCreate architecture... 
    Principal

    LTM

    New Brunswick, NJ
    7 days ago
  • Role: Principal Scientist Stability overseeing stability strategies and programs for commercial large molecule biologics, including Drug Substances and Drug Products. Responsibilities: lead stability program development and maintenance, author/study protocols, review stability... 
    Principal

    Bristol Myers Squibb

    New Brunswick, NJ
    5 days ago
  •  ...Johnson & Johnson seeks a Principal Data Engineer to lead enterprise data integration strategy and architecture for a 2-year duration role. The position requires owning technical decisions, driving scalable solutions across cloud platforms, and partnering with cross-functional... 
    Principal

    Johnson & Johnson

    New Brunswick, NJ
    1 day ago
  • Job ID: 24633021Reference Number: 25-00081Title: Principal AWS Networking EngineerLocation: Iselin, NJ, 08830Posted Date: 2025-02-04Company: HAN StaffingPrincipal AWS Networking Engineer
    Principal

    HAN Staffing

    Iselin, NJ
    4 days ago
  • Job DescriptionPrincipal - Medical Devices Commercial Transformation, Life SciencesInfosys Consulting is seeking an entrepreneurial Principal to grow our Medical Devices Commercial practice by helping clients modernize the technology behind their customer-facing functions... 
    Principal
    Full time
    Contract work
    Temporary work

    Infosys Technologies

    Somerset, NJ
    5 days ago
  • $96.8k - $137k

     ...excited to invite applications for the position of Enterprise Architect within our Advance Tech, Architecture & Analytics Team.You will...  ...Architecture framework, including technology, data, and security architecture.Collaborate with stakeholders to identify and apply... 
    Hourly pay
    Local area
    Relocation

    Colgate-Palmolive

    Piscataway, NJ
    6 days ago
  • Merck & Co. is seeking a Senior Director (Sr. Principal Scientist) to lead the planning and direction of clinical research for oncology medicines. This role oversees study design, placement, monitoring, analysis, regulatory reporting, and publication across all development... 
    Principal

    Merck & Co. Inc

    Rahway, NJ
    2 days ago
  • $120.5k - $231k

     ...and building trust in how we show up, everywhere & always. Want in? Join the #VTeamLife.What you'll be doing...As a member of the Security Engineering & Operations team, you will be responsible for the end-to-end administration, maintenance, and day-to-day operation of... 
    Principal
    Full time
    Temporary work
    Part time
    Work experience placement
    Work at office
    Work from home
    Shift work
    Afternoon shift
    3 days per week

    Verizon

    Basking Ridge, NJ
    7 days ago
  •  ...Principal Lab Technician Recruitment/Posting Title - Principal Lab Technician Job Category - Staff & Executive - Research Support (Laboratory/Non-Laboratory) Department - RWJ - Neurosurgery Overview - New Jersey's academic health center, Rutgers Biomedical... 
    Principal
    Full time
    Work at office
    Shift work

    Rutgers Biomedical and Health Sciences

    Piscataway, NJ
    2 days ago
  • $154.38k - $193.13k

    Job DescriptionInfosys Consulting’s CMT Practice is seeking a Principal Level Management Consultant with experience across one or more domain areas in the Communications, Media and Technology industry, including Customer Relationship Management (CRM), Customer Care Operations... 
    Principal
    Full time
    Temporary work

    Infosys Technologies

    Somerset, NJ
    6 days ago
  • $190.8k - $300.3k

     ...Senior Principal Scientist in Regulatory Affairs at Merck responsible for developing and implementing worldwide regulatory strategies for General Medicine and Immunology programs. The role involves independent project management, direct agency interactions, and leadership... 
    Principal
    Worldwide

    Merck

    Rahway, NJ
    10 days ago
  •  ...Jewish values to life in a way that is meaningful, joyful, and developmentally appropriate. Position Overview The Judaic Studies Principal oversees curriculum development, faculty mentorship, and the spiritual culture of the school, while partnering closely with... 
    Principal
    Work at office

    Yeshivat Netivot Montessori

    East Brunswick, NJ
    16 days ago
  • $170k - $200k

     ...with trusted transparency. ROLE SUMMARY We are seeking a Principal Architect for Network Services who will understand existing...  ...readiness, and standards adherence. Collaborate across Cloud, Security, Platform, and Application Architecture teams. Provide architectural... 
    Principal

    EOS

    New Brunswick, NJ
    17 days ago
  • Function Lead and manage epitaxial growth activities for the production and development of laser and detector materials, including EMLs and DFBs. Ensure efficient and cost-effective operation of MOCVD reactors, and maintain a reliable supply of epitaxial materials for...
    Principal
    Full time

    LigentCom Photonics

    South Plainfield, NJ
    1 day ago
  • $154.38k - $193.13k

    Job DescriptionAI Architect, AI & AutomationAbout the Role The applicant should have deep, hands-on experience architecting, designing...  ...responsible AI practices, model risk management, and data privacy/security considerations.Experience integrating AI/GenAI capabilities... 
    Principal
    Full time
    Temporary work
    Work experience placement

    Infosys Technologies

    Somerset, NJ
    7 days ago
  • $210k - $256.67k

     ...New Jersey, New York, Texas, WashingtonCompanyITL USA Interest GroupInfosys Limited DomainManufacturing, Retail and Consumer Packed Goods, UtilitiesSkillsetProcess|Consulting processes|Technology Consulting process Job RoleSenior Principal - Business Consulting: 145272BR
    Principal
    Full time
    Temporary work
    Remote work

    Infosys Technologies

    Bridgewater, NJ
    7 days ago
  • Job Summary: Take lead on various engineering efforts in an advanced InP BH laser fab, including process development, yield improvement, trouble shooting, tool qualification, etc. Responsibilities: Design and DOE to develop processes (photolithography, chemical...
    Principal
    Full time

    LigentCom Photonics

    South Plainfield, NJ
    1 day ago
  • Job Title: Principal Power Electronics Applications Engineer - GaN / SiCLocation: Somerville, MA, - will provide relocation assistance!Compensation: $175K - $220K DOE plus equityRequirement: MS or PhD w/ 5+ years of Wide Bandgap (WBG) Power Semiconductor (GaN / SiC) Applications... 
    Principal
    Relocation package

    CyberCoders

    Bridgewater, NJ
    3 days ago
  • $282.2k

     ...Senior Principal Scientist position in breast cancer clinical research at a pharmaceutical company. Responsibilities include developing clinical trial strategies, evaluating preclinical data, managing ongoing studies, and collaborating across functional teams to advance... 
    Principal

    Merck

    Rahway, NJ
    2 days ago
  • Merck & Co., Inc. in Rahway, NJ seeks a Principal Scientist to provide strategic biomarker leadership across Neuroscience programs, spanning translational and clinical biomarker strategies from early to late development. The role emphasizes decision-centric plans integrating... 
    Principal

    MSD Malaysia

    Rahway, NJ
    4 days ago
  •  ...Role Associate Principal Scientist supporting biologics sterile product development within the Sterile Product Development (SPD) group. Objectives Lead innovative biologics formulation and process development, support early and late-stage candidates, and contribute... 
    Principal

    Scorpion Therapeutics

    Rahway, NJ
    5 days ago
  •  ...Senior Principal Scientist leading nonclinical drug safety strategy for immunology programs at Merck. Responsible for overseeing development progression, regulatory submissions, and post-marketing support while mentoring scientists and influencing cross-functional partnerships... 
    Principal

    Merck

    Rahway, NJ
    10 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Security Architect. Be the first to apply!