Scientist - Molecular Cloning & Automation

Job Description

Job Description

Company Description

The work we do at Eurofins Professional Scientific Services matters, and so do our employees. At Eurofins PSS, we put a focus on your professional growth. We provide our employees the ability to break into the biopharmaceutical industry and grow from the bottom up. We have the supportive teams and tools available to invest in you while also affording you work-life balance and a competitive benefits package.

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier, and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic, and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical, and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences, and in the support of clinical studies.

Join us in shaping a safer, healthier, and more sustainable world. Explore opportunities with Eurofins and be part of a global team driving scientific excellence. Apply today and make a meaningful impact!

Job Description

We are seeking a skilled Scientist – Molecular Cloning & Automation to lead plasmid design, DNA assembly, and scalable workflow development. You will apply advanced cloning strategies and build automated solutions to support high-throughput construct generation, ensuring quality, efficiency, and on-time delivery across multiple programs.

Job Responsibilities

• Design and execute end-to-end plasmid workflows, translating protein or guide RNA sequences into verified, production-ready constructs
• Select and apply appropriate cloning strategies (e.g., Golden Gate, Gibson Assembly, restriction-ligation) based on construct complexity
• Develop, implement, and scale automated workflows for high-throughput plasmid production, including:
  • Liquid handling platforms (Hamilton STAR, Opentrons, Beckman Biomek)
  • Automated colony picking systems (e.g., QPix)
  • High-throughput miniprep processes
• Establish and manage tiered QC pipelines (colony PCR, restriction digest, Sanger and/or long-read sequencing) while maintaining accurate construct documentation
• Oversee CRO and vendor relationships for outsourced cloning and gene synthesis, including construct submission, timeline management, and QC review
• Partner cross-functionally to deliver constructs on time, managing multiple concurrent requests with clear, proactive communication

Qualifications

Required Qualifications:

• B.S. with 5+ years, M.S. with 3+ years, or Ph.D. with 2+ years of relevant industry experience in Molecular Biology, Biochemistry, Bioengineering, or a related field
• Expert proficiency in Golden Gate, Gibson Assembly, and restriction-ligation cloning, with the ability to select optimal strategies
• Strong knowledge of plasmid biology, including origins of replication, selection markers, promoter design, codon optimization, and management of recombination-prone sequences
• Hands-on PCR experience, including polymerase selection (e.g., Q5, Phusion), primer design, and troubleshooting challenging amplicons.
• Experience managing CRO/vendors for gene synthesis or outsourced cloning
• Proficiency with Benchling or similar ELN for construct tracking and QC documentation
• Familiarity with sequence design and visualization tools (e.g., SnapGene, Geneious)
• Proven ability to manage multiple simultaneous cloning projects and deliver high-quality constructs on timeline
• Strong communication skills with a collaborative, cross-functional mindset

Preferred Qualifications:

• Experience programming, validating, and troubleshooting liquid handling platforms (e.g., Hamilton, Beckman, Tecan, Opentrons)
• Familiarity with automated colony picking and high-throughput plasmid prep workflows
• Experience with pooled oligo cloning, including library design, bias mitigation, and NGS-based QC analysis
• Background in lentiviral or pooled library cloning workflows
• Experience with long-read sequencing technologies (PacBio or Nanopore)
• Exposure to gene therapy applications (AAV, LVV, mRNA, CAR-T) and downstream construct use
• Experience supporting IVT template design or mRNA production workflows
• Authorization to work in the U.S. without sponsorship

Additional Information

What to Expect in the Hiring Process: 

• 10-15 Minute Phone Interview with Region Recruiter
• 45-60 Minute Virtual Interview with Manager and/or Group Leader
• 30 Minute In-Person Onsite Meeting with the Team

Additional Details: 

The position is  Full Time, Monday-Friday, 8am-5pm.  Candidates currently living within a commutable distance of  Boston, MA  are encouraged to apply.

Excellent full-time benefits include:

• Comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Hourly rate is between $45.00-$48.00, depending on education and experience 

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.